Efflux of lipid from fibroblasts to apolipoproteins: dependence on elevated levels of cellular unesterified cholesterol.

Autor: JK Bielicki, WJ Johnson, RB Weinberg, JM Glick, GH Rothblat

Publikováno v: Journal of Lipid Research, Vol 33, Iss 11, Pp 1699-1709 (1992)

Earlier work from this laboratory showed that enrichment of cells with free cholesterol enhanced the efflux of phospholipid to lipoprotein acceptors, suggesting that cellular phospholipid may contribute to high density lipoprotein (HDL) structure and

Externí odkaz: https://doaj.org/article/c56831ef068d4b54bacaf7b7b99e60c2

Cholesterol efflux from cells to immunopurified subfractions of human high density lipoprotein: LP-AI and LP-AI/AII.

Autor: WJ Johnson, EP Kilsdonk, A van Tol, MC Phillips, GH Rothblat

Publikováno v: Journal of Lipid Research, Vol 32, Iss 12, Pp 1993-2000 (1991)

Using immunoaffinity chromatography, we separated human high density lipoprotein (HDL) into two subfractions: LP-AI, in which all particles contain apolipoprotein A-I (apoA-I) but no apoA-II, and LP-AI/AII, in which all particles contain both apoA-I

Externí odkaz: https://doaj.org/article/edfc1d24b9f94a8ea84a52d3e8b96d95

The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein

Autor: William Davidson, Lund-Katz S, Wj, Johnson, Gm, Anantharamaiah, Mn, Palgunachari, Jp, Segrest, Gh, Rothblat, Mc, Phillips

Publikováno v: Europe PubMed Central

The influence of apolipoprotein conformation on the ability of high density lipoprotein (HDL) to remove cellular free cholesterol (FC) has not been studied in detail. To address the effects of amphipathic alpha-helix structure on cellular FC efflux,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c7ae49629d3718f6cf893dbaaedc0230
https://pubmed.ncbi.nlm.nih.gov/8083197

Importance of evaluating cell cholesterol influx with efflux in determining the impact of human serum on cholesterol metabolism and atherosclerosis.

Autor: Weibel GL; From the Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, PA (G.L.W., D.D.-S., D.K.S., G.H.R., M.d.l.L.-M.); Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.P.R.); and School of Public Health and School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (A.N.W.)., Drazul-Schrader D, Shivers DK, Wade AN, Rothblat GH, Reilly MP, de la Llera-Moya M

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2014 Jan; Vol. 34 (1), pp. 17-25. Date of Electronic Publication: 2013 Nov 07.

Serum albumin acts as a shuttle to enhance cholesterol efflux from cells.

Autor: Sankaranarayanan S; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA., de la Llera-Moya M; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA., Drazul-Schrader D; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA., Phillips MC; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA., Kellner-Weibel G; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA., Rothblat GH; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA.

Publikováno v: Journal of lipid research [J Lipid Res] 2013 Mar; Vol. 54 (3), pp. 671-676. Date of Electronic Publication: 2013 Jan 03.