Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Gh, Reaman"'
Autor:
NA Heerema, DC Arthur, H Sather, V Albo, J Feusner, BJ Lange, PG Steinherz, P Zeltzer, D Hammond, GH Reaman
Publikováno v:
Blood. 83:2274-2284
Cytogenetic analyses of pretreatment bone marrows were performed at local institutions as part of Childrens Cancer Group (CCG) protocol CCG- 107 for infants less than 1 year of age with previously untreated acute lymphoblastic leukemia (ALL). Cytogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cacb438fbb96559145a8af49dd54e489
https://doi.org/10.1182/blood.v83.8.2274.bloodjournal8382274
https://doi.org/10.1182/blood.v83.8.2274.bloodjournal8382274
Autor:
Fatih M. Uckun, Stork L, Seibel N, Sarquis M, Bedros C, Sather H, Sensel M, Gh, Reaman, Ps, Gaynon
Publikováno v:
Europe PubMed Central
We used highly sensitive multiparameter flow cytometry and blast colony assays to quantify the leukemic progenitor cell (LPC) burden of postinduction chemotherapy bone marrows from newly diagnosed and relapsed pediatric patients with acute lymphoblas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::136be694118f2ada42b9dcf434105474
https://pubmed.ncbi.nlm.nih.gov/10955793
https://pubmed.ncbi.nlm.nih.gov/10955793
Autor:
Sun L, Ml, Crotty, Sensel M, Sather H, Navara C, Nachman J, Pg, Steinherz, Ps, Gaynon, Seibel N, Mao C, Vassilev A, Gh, Reaman, Fatih M. Uckun
Publikováno v:
Europe PubMed Central
Ikaros, a zinc finger-containing DNA-binding protein, is required for normal lymphocyte development. Germ-line mutant mice that express only non-DNA binding dominant-negative "leukemogenic" Ikaros isoforms lacking critical NH2-terminal zinc fingers d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cb0fd748ef5a468297a899932985fec4
https://pubmed.ncbi.nlm.nih.gov/10473095
https://pubmed.ncbi.nlm.nih.gov/10473095
Autor:
Fatih M. Uckun, Hn, Sather, Ps, Gaynon, Dc, Arthur, Me, Trigg, Dg, Tubergen, Nachman J, Pg, Steinherz, Mg, Sensel, Gh, Reaman
Publikováno v:
Europe PubMed Central
Leukemic cells from a significant number of children with acute lymphoblastic leukemia (ALL) express protein antigens characteristic of both lymphoid and myeloid cells, yet the clinical significance of this immunophenotype has remained controversial.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5923141e5efb2d047f3a7e235ddff1b4
https://pubmed.ncbi.nlm.nih.gov/9207434
https://pubmed.ncbi.nlm.nih.gov/9207434
Publikováno v:
Blood. 88(1)
Clinical drug resistance may be attributed to the simultaneous selection and expression of genes modulating the uptake and metabolism of chemotherapeutic agents. P-glycoprotein (P-gp) functions as a membrane-associated drug efflux pump whose increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c7c1c82f1f717d4526a66013c7a90a
https://pubmed.ncbi.nlm.nih.gov/8704189
https://pubmed.ncbi.nlm.nih.gov/8704189
Publikováno v:
Blood. 81(9)
Acute lymphoblastic leukemia (ALL) in infants generally shows distinctive biologic features and has a poor prognosis. Cytogenetic studies indicate that many infant leukemias have chromosome 11q23 translocations. Because of these findings and the dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d3c59163712bb8e2f6dc3d1f2681d4
https://pubmed.ncbi.nlm.nih.gov/8481519
https://pubmed.ncbi.nlm.nih.gov/8481519
Publikováno v:
Blood. 56:380-382
Purine nucleoside phosphorylase (PNP) activity has been measured in the lymphoblasts of 22 patients with acute lymphoblastic leukemia (ALL) and correlated with routine immunologic cell surface markers. Fourteen of the 22 patients were considered to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f932b3336d0e1f07c05b7d99e02a5f6
https://doi.org/10.1182/blood.v56.3.380.bloodjournal563380
https://doi.org/10.1182/blood.v56.3.380.bloodjournal563380
Autor:
PA Dinndorf, GH Reaman
Publikováno v:
Blood. 68(4)
Since the prognosis of infants with acute lymphoblastic leukemia (ALL) is so poor, it has been suggested that these leukemias may not be lymphoid in origin, but may originate from stem cell, myeloid, or megakaryocytic progenitors. Alternately it has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bd8800b14de2b08b79ff7e6c9c1bb6
https://pubmed.ncbi.nlm.nih.gov/3489496
https://pubmed.ncbi.nlm.nih.gov/3489496
Publikováno v:
AJR. American journal of roentgenology. 132(1)
Radiographic manifestations of Burkitt's lymphoma in 40 American patients are presented. Pleural effusions were the most common intrathoracic abnormality and were correlated with abdominal ascites more often than with intrathoracic tumor. Tumor invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c0b56fe54eb365ead116415c33ba2b
https://pubmed.ncbi.nlm.nih.gov/103382
https://pubmed.ncbi.nlm.nih.gov/103382
Autor:
Pj, Tortolani, Bk, Lal, Riva A, Ja, Johnston, Yq, Chen, Gh, Reaman, Beckwith M, Longo D, Jr, Ortaldo, Bhatia K, McGrath I, Kehrl J, Tuscano J, Daniel McVicar, Shea Jj, O.
Publikováno v:
Europe PubMed Central
Members of the Janus family (JAK) of protein tyrosine kinases are critical enzymes in signaling pathways via hematopoietin receptors. We have cloned JAK3, which unlike other known family members (JAK1, JAK2, and TYK2) is preferentially expressed in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a7bef567635d3542d74af278680def90
http://europepmc.org/abstract/med/7594533
http://europepmc.org/abstract/med/7594533
