Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gh, Reaman"'
Autor:
NA Heerema, DC Arthur, H Sather, V Albo, J Feusner, BJ Lange, PG Steinherz, P Zeltzer, D Hammond, GH Reaman
Publikováno v:
Blood. 83:2274-2284
Cytogenetic analyses of pretreatment bone marrows were performed at local institutions as part of Childrens Cancer Group (CCG) protocol CCG- 107 for infants less than 1 year of age with previously untreated acute lymphoblastic leukemia (ALL). Cytogen
Autor:
Fatih M. Uckun, Stork L, Seibel N, Sarquis M, Bedros C, Sather H, Sensel M, Gh, Reaman, Ps, Gaynon
Publikováno v:
Europe PubMed Central
We used highly sensitive multiparameter flow cytometry and blast colony assays to quantify the leukemic progenitor cell (LPC) burden of postinduction chemotherapy bone marrows from newly diagnosed and relapsed pediatric patients with acute lymphoblas
Autor:
Sun L, Ml, Crotty, Sensel M, Sather H, Navara C, Nachman J, Pg, Steinherz, Ps, Gaynon, Seibel N, Mao C, Vassilev A, Gh, Reaman, Fatih M. Uckun
Publikováno v:
Europe PubMed Central
Ikaros, a zinc finger-containing DNA-binding protein, is required for normal lymphocyte development. Germ-line mutant mice that express only non-DNA binding dominant-negative "leukemogenic" Ikaros isoforms lacking critical NH2-terminal zinc fingers d
Autor:
Fatih M. Uckun, Hn, Sather, Ps, Gaynon, Dc, Arthur, Me, Trigg, Dg, Tubergen, Nachman J, Pg, Steinherz, Mg, Sensel, Gh, Reaman
Publikováno v:
Europe PubMed Central
Leukemic cells from a significant number of children with acute lymphoblastic leukemia (ALL) express protein antigens characteristic of both lymphoid and myeloid cells, yet the clinical significance of this immunophenotype has remained controversial.
Publikováno v:
Blood. 88(1)
Clinical drug resistance may be attributed to the simultaneous selection and expression of genes modulating the uptake and metabolism of chemotherapeutic agents. P-glycoprotein (P-gp) functions as a membrane-associated drug efflux pump whose increase
Publikováno v:
Blood. 81(9)
Acute lymphoblastic leukemia (ALL) in infants generally shows distinctive biologic features and has a poor prognosis. Cytogenetic studies indicate that many infant leukemias have chromosome 11q23 translocations. Because of these findings and the dist
Publikováno v:
Pediatric blood & cancer [Pediatr Blood Cancer] 2013 Jun; Vol. 60 (6), pp. 897-8. Date of Electronic Publication: 2013 Mar 28.
Publikováno v:
Blood. 56:380-382
Purine nucleoside phosphorylase (PNP) activity has been measured in the lymphoblasts of 22 patients with acute lymphoblastic leukemia (ALL) and correlated with routine immunologic cell surface markers. Fourteen of the 22 patients were considered to h
Autor:
PA Dinndorf, GH Reaman
Publikováno v:
Blood. 68(4)
Since the prognosis of infants with acute lymphoblastic leukemia (ALL) is so poor, it has been suggested that these leukemias may not be lymphoid in origin, but may originate from stem cell, myeloid, or megakaryocytic progenitors. Alternately it has
Publikováno v:
AJR. American journal of roentgenology. 132(1)
Radiographic manifestations of Burkitt's lymphoma in 40 American patients are presented. Pleural effusions were the most common intrathoracic abnormality and were correlated with abdominal ascites more often than with intrathoracic tumor. Tumor invol