Zobrazeno 1 - 10
of 327
pro vyhledávání: '"Geum-Sook Hwang"'
Autor:
Cho-Rong Lee, Jungyo Suh, Dongjun Jang, Bo-Yeong Jin, Jaeso Cho, Moses Lee, Hyungtai Sim, Minyong Kang, Jueun Lee, Ju Hyun Park, Kyoung-Hwa Lee, Geum-Sook Hwang, Kyung Chul Moon, Cheryn Song, Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim, Sung-Yup Cho, Murim Choi, Chang Wook Jeong
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1807-1815 (2024)
Abstract TFE3-rearranged renal cell cancer (tRCC) is a rare form of RCC that involves chromosomal translocation of the Xp11.2 TFE3 gene. Despite its early onset and poor prognosis, the molecular mechanisms of the pathogenesis of tRCC remain elusive.
Externí odkaz:
https://doaj.org/article/bbfddcce0aa9476695825f4d115b7c2a
Autor:
Sunho Lee, Jueun Lee, Kwang-Soo Lyoo, Yourim Shin, Dong-Min Shin, Jun-Won Kim, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Geum-Sook Hwang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, notably delta and omicron, has significantly accelerated the global pandemic, worsening conditions worldwide. However, there is a lack of research con
Externí odkaz:
https://doaj.org/article/1d2cf9cff9d64500a8aeafe8c10ba2de
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract This study investigated chronic and repeated sleep deprivation (RSD)-induced neuronal changes in hexosamine biosynthetic pathway/O-linked N-acetylglucosamine (HBP/O-GlcNAc) cycling of glucose metabolism and further explored the role of alter
Externí odkaz:
https://doaj.org/article/1f80242c46a64c2ab0ff1871f8635702
Autor:
Mihee Oh, Seo Young Jang, Ji-Yoon Lee, Jong Woo Kim, Youngae Jung, Jiwoo Kim, Jinho Seo, Tae-Su Han, Eunji Jang, Hye Young Son, Dain Kim, Min Wook Kim, Jin-Sung Park, Kwon-Ho Song, Kyoung-Jin Oh, Won Kon Kim, Kwang-Hee Bae, Yong-Min Huh, Soon Ha Kim, Doyoun Kim, Baek-Soo Han, Sang Chul Lee, Geum-Sook Hwang, Eun-Woo Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls intracellular phospholipid metabolism and contributes to ferroptosis resistance. A m
Externí odkaz:
https://doaj.org/article/f90ee655100f4a7dbd4a8f6ac8458b81
Autor:
Soie Kwon, Jin Seong Hyeon, Youngae Jung, Lilin Li, Jung Nam An, Yong Chul Kim, Seung Hee Yang, Tammy Kim, Dong Ki Kim, Chun Soo Lim, Geum-Sook Hwang, Jung Pyo Lee
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 4, Pp 445-459 (2023)
Background As a leading cause of chronic kidney disease, clinical demand for noninvasive biomarkers of diabetic kidney disease (DKD) beyond proteinuria is increasing. Metabolomics is a popular method to identify mechanisms and biomarkers. We investig
Externí odkaz:
https://doaj.org/article/a572f3adea084af395b2f85218bacd8e
Autor:
Hyuek Jong Lee, Jueun Lee, Myung Jin Yang, Young-Chan Kim, Seon Pyo Hong, Jung Mo Kim, Geum-Sook Hwang, Gou Young Koh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Active thermogenesis in the brown adipose tissue (BAT) facilitating the utilization of lipids and glucose is critical for maintaining body temperature and reducing metabolic diseases, whereas inactive BAT accumulates lipids in brown adipocyt
Externí odkaz:
https://doaj.org/article/6a7b56122764406f9ab2bf5c8e68b113
Autor:
Jin-Hyuck Jeong, Jun-Seok Han, Youngae Jung, Seung-Min Lee, So-Hyun Park, Mooncheol Park, Min-Gi Shin, Nami Kim, Mi Sun Kang, Seokho Kim, Kwang-Pyo Lee, Ki-Sun Kwon, Chun-A. Kim, Yong Ryoul Yang, Geum-Sook Hwang, Eun-Soo Kwon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Although diet modulates aging, little is known about whether and how nutrient regulates longevity. Here, the authors show that glucose-restricted diets prolong longevity through series of conserved factors, such as neuronal AMPK, neuropeptide, AdipoR
Externí odkaz:
https://doaj.org/article/9d96c287f7ab4e7690ab27d6f5c60c71
Autor:
Hee-Hoon Kim, Young-Ri Shim, Ha Neul Kim, Keungmo Yang, Tom Ryu, Kyurae Kim, Sung Eun Choi, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyemi Shin, Jae Myoung Suh, Youngae Jung, Geum-Sook Hwang, Won Kim, Seok-Hwan Kim, Hyuk Soo Eun, Je Kyung Seong, Won-Il Jeong
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112636- (2023)
Summary: Obesity-mediated hypoxic stress underlies inflammation, including interferon (IFN)-γ production by natural killer (NK) cells in white adipose tissue. However, the effects of obesity on NK cell IFN-γ production remain obscure. Here, we show
Externí odkaz:
https://doaj.org/article/d0d7fa527d414e97b49ac647aa5bdc1a
Autor:
Songyeon Lee, Byung-Joon Seung, In Seok Yang, Jueun Lee, Taewoong Ha, Hee-Myung Park, Jae-Ho Cheong, Sangwoo Kim, Jung-Hyang Sur, Geum-Sook Hwang, Hojung Nam
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Measurement(s) Metabolite Technology Type(s) 1H nuclear magnetic resonance spectroscopy Factor Type(s) Age • Breeds • Sex • ER status • HER2 status • Histological grade • Neutral status Sample Characteristic - Organism Canis lupus familia
Externí odkaz:
https://doaj.org/article/f8081ca59ffb4e038f0eed47248114e4
Autor:
Bokyung Kim, Jae-Jin Lee, Ji Soo Shin, Ji-Wan Suh, Sunhee Jung, Geum-Sook Hwang, Hee-Yoon Lee, Kong-Joo Lee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Mitochondrial oxidative phosphorylation (OXPHOS) has become an attractive target in anti-cancer studies in recent years. In this study, we found that a small molecule phenylbutenoid dimer NMac1 (Nm23-H1 activator 1), (±)-trans-3-(3,4-dimeth
Externí odkaz:
https://doaj.org/article/989bf2ab2a3c43b3b73141e200c9de2b