Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Geula Gibori"'
Publikováno v:
Molecular and Cellular Endocrinology. 356:80-87
Prolactin is a hormone that is essential for normal reproduction and signals through two types of receptors. Not only is the classical long form of the prolactin receptor identified, but so are many short form receptors in rodents and human tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff92b1113c98e6806991d8d8c3974a20
https://doi.org/10.1016/j.mce.2011.05.004
https://doi.org/10.1016/j.mce.2011.05.004
Publikováno v:
Hormone and Metabolic Research. 43:931-937
To date the best defined function of prolactin (PRL) is its action on the ovary and mammary gland, although it has also been shown to have an effect on lipid metabolism. Using mice engineered to express only the long form of the prolactin receptor (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b118da79d6cf9c8f8d30aa40680dd5d6
https://doi.org/10.1055/s-0031-1291182
https://doi.org/10.1055/s-0031-1291182
Autor:
Nadine Binart, Geula Gibori, Y. Sangeeta Devi, Aurora Shehu, Julia Halperin, Jamie Le, Anita M. Seibold, Evelyn T. Maizels, Lei Bao
Publikováno v:
Journal of Biological Chemistry. 286:7609-7618
Prolactin (PRL) is essential for normal reproduction and signals through two types of receptors, the short (PRL-RS) and long (PRL-RL) form. We have previously shown that transgenic mice expressing only PRL-RS (PRLR−/−RS) display abnormal follicul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b616b7471f4d8416b142bae0fa2ae2
https://doi.org/10.1074/jbc.m110.166603
https://doi.org/10.1074/jbc.m110.166603
Autor:
Bradley J. Merrill, Julia Halperin, G. Gibori, Aurora Shehu, Jifang Mao, Geula Gibori, Y. Sangeeta Devi, Jamie Le, Hiroaki Kiyokawa
Publikováno v:
Molecular Endocrinology. 22:2268-2277
Our laboratory has previously cloned and purified a protein named PRAP (prolactin receptor-associated protein) that was shown to be a novel 17beta-hydroxysteroid dehydrogenase (HSD) enzyme with dual activity. This enzyme, renamed HSD17B7 or PRAP/17be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafa759d0bee80e59d539be922657759
https://doi.org/10.1210/me.2008-0165
https://doi.org/10.1210/me.2008-0165
Autor:
Michael Risk, Laura T. Goldsmith, Geula Gibori, Jennifer M. Bowen-Shauver, Aurora Shehu, Carlos Stocco, Jifang Mao
Publikováno v:
Endocrinology. 146:2807-2816
Prolactin receptor-associated protein (PRAP) originally cloned in our laboratory was shown to be a novel, luteal isoform of 17β hydroxysteroid dehydrogenase 7 (17βHSD7). In this study, we cloned the promoter region of rat PRAP/17βHSD7 and investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ce2381ef19e00eeba9a426418b3def
https://doi.org/10.1210/en.2004-1673
https://doi.org/10.1210/en.2004-1673
Publikováno v:
Journal of Molecular Endocrinology. 32:365-383
Nuclear factor kappa B (NFkappaB) is an important intracellular conveyor of extracellular signals and modulates a number of gene responses. Due to the potential significance of NFkappaB in regulating ovarian gene expression, we examined in the rat: (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726ac0d52a6637f49bc14d84a5987ca5
https://doi.org/10.1677/jme.0.0320365
https://doi.org/10.1677/jme.0.0320365
Publikováno v:
Biology of Reproduction. 68:2322-2330
We evaluated the involvement of the in vivo hormonal environment on the ability of the rat corpus luteum (CL) to undergo apoptosis. Gel electrophoretic DNA fragmentation analysis revealed no apoptosis in CL isolated either the 2 last days of pregnanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d941d65193b86923640757cf112188cb
https://doi.org/10.1095/biolreprod.102.013540
https://doi.org/10.1095/biolreprod.102.013540
Autor:
Nelson D. Horseman, Y Gu, Geula Gibori, Jennifer M. Bowen-Shauver, Lei Bao, Anne Prigent-Tessier, Susan Ferguson-Gottschall, G. Gibori, Christian Tessier, Carlos M. Telleria
Publikováno v:
Biology of Reproduction. 68:1687-1694
Successful pregnancy requires profound differentiation and reorganization of the uterine tissues including, as pregnancy progresses, extensive apoptosis of decidual tissue to accommodate the developing conceptus. We have previously shown a positive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e95db787a3806176a1a696b6d83f74f9
https://doi.org/10.1095/biolreprod.102.011684
https://doi.org/10.1095/biolreprod.102.011684
Publikováno v:
Biology of Reproduction. 68:151-158
Progesterone production by the corpus luteum (CL) is essential for preparation of the endometrium for implantation and for the maintenance of gestation. Progesterone modulates its own production and opposes functional luteal regression induced by exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8057729731e6ce6765e0a951253f95a1
https://doi.org/10.1095/biolreprod.102.007898
https://doi.org/10.1095/biolreprod.102.007898
Publikováno v:
Biology of Reproduction. 66:1540-1547
Androgens, in concert with lactogenic hormones, contribute to the maintenance of function of the corpus luteum (CL) in pregnant rats. Whereas some of the androgenic actions in the CL are clearly mediated by intracrine conversion to estrogen, pure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd29b2938387909cbbdc723801a52b2
https://doi.org/10.1095/biolreprod66.5.1540
https://doi.org/10.1095/biolreprod66.5.1540