Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Geula, Gibori"'
Publikováno v:
Molecular and Cellular Endocrinology. 356:80-87
Prolactin is a hormone that is essential for normal reproduction and signals through two types of receptors. Not only is the classical long form of the prolactin receptor identified, but so are many short form receptors in rodents and human tissues.
Publikováno v:
Hormone and Metabolic Research. 43:931-937
To date the best defined function of prolactin (PRL) is its action on the ovary and mammary gland, although it has also been shown to have an effect on lipid metabolism. Using mice engineered to express only the long form of the prolactin receptor (P
Autor:
Nadine Binart, Geula Gibori, Y. Sangeeta Devi, Aurora Shehu, Julia Halperin, Jamie Le, Anita M. Seibold, Evelyn T. Maizels, Lei Bao
Publikováno v:
Journal of Biological Chemistry. 286:7609-7618
Prolactin (PRL) is essential for normal reproduction and signals through two types of receptors, the short (PRL-RS) and long (PRL-RL) form. We have previously shown that transgenic mice expressing only PRL-RS (PRLR−/−RS) display abnormal follicul
Autor:
Bradley J. Merrill, Julia Halperin, G. Gibori, Aurora Shehu, Jifang Mao, Geula Gibori, Y. Sangeeta Devi, Jamie Le, Hiroaki Kiyokawa
Publikováno v:
Molecular Endocrinology. 22:2268-2277
Our laboratory has previously cloned and purified a protein named PRAP (prolactin receptor-associated protein) that was shown to be a novel 17beta-hydroxysteroid dehydrogenase (HSD) enzyme with dual activity. This enzyme, renamed HSD17B7 or PRAP/17be
Autor:
Michael Risk, Laura T. Goldsmith, Geula Gibori, Jennifer M. Bowen-Shauver, Aurora Shehu, Carlos Stocco, Jifang Mao
Publikováno v:
Endocrinology. 146:2807-2816
Prolactin receptor-associated protein (PRAP) originally cloned in our laboratory was shown to be a novel, luteal isoform of 17β hydroxysteroid dehydrogenase 7 (17βHSD7). In this study, we cloned the promoter region of rat PRAP/17βHSD7 and investig
Publikováno v:
Journal of Molecular Endocrinology. 32:365-383
Nuclear factor kappa B (NFkappaB) is an important intracellular conveyor of extracellular signals and modulates a number of gene responses. Due to the potential significance of NFkappaB in regulating ovarian gene expression, we examined in the rat: (
Publikováno v:
Biology of Reproduction. 68:2322-2330
We evaluated the involvement of the in vivo hormonal environment on the ability of the rat corpus luteum (CL) to undergo apoptosis. Gel electrophoretic DNA fragmentation analysis revealed no apoptosis in CL isolated either the 2 last days of pregnanc
Autor:
Nelson D. Horseman, Y Gu, Geula Gibori, Jennifer M. Bowen-Shauver, Lei Bao, Anne Prigent-Tessier, Susan Ferguson-Gottschall, G. Gibori, Christian Tessier, Carlos M. Telleria
Publikováno v:
Biology of Reproduction. 68:1687-1694
Successful pregnancy requires profound differentiation and reorganization of the uterine tissues including, as pregnancy progresses, extensive apoptosis of decidual tissue to accommodate the developing conceptus. We have previously shown a positive c
Publikováno v:
Biology of Reproduction. 68:151-158
Progesterone production by the corpus luteum (CL) is essential for preparation of the endometrium for implantation and for the maintenance of gestation. Progesterone modulates its own production and opposes functional luteal regression induced by exo
Publikováno v:
Biology of Reproduction. 66:1540-1547
Androgens, in concert with lactogenic hormones, contribute to the maintenance of function of the corpus luteum (CL) in pregnant rats. Whereas some of the androgenic actions in the CL are clearly mediated by intracrine conversion to estrogen, pure and