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Leishmania aethiopica cell‐to‐cell spreading involves caspase‐3, AkT, and NF‐κB but not PKC‐δ activation and involves uptake of LAMP‐1‐positive bodies containing parasites

Autor: Ranatunga, Medhavi, Rai, Rajeev, Richardson, Simon C. W., Dyer, Paul D. R., Harbige, Laurence, Deacon, Andrew, Pecorino, Lauren, Getti, Giulia T. M.

Development of human leishmaniasis is dependent on the ability of intracellular Leishmania parasites to spread and enter macrophages. The mechanism through which free promastigotes and amastigotes bind and enter host macrophages has been previously i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c515b13f6c53bf5ec8e283f62d8fdb89
https://arro.anglia.ac.uk/id/eprint/705091/1/Ranatunga_et_al_2019.pdf

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Leishmania aethiopica cell-to-cell spreading involves caspase-3, AkT, and NF-κB but not PKC-δ activation and involves uptake of LAMP-1-positive bodies containing parasites.

Autor: Ranatunga M; University of Greenwich at Medway, Kent, UK., Rai R; University of Greenwich at Medway, Kent, UK., Richardson SCW; University of Greenwich at Medway, Kent, UK., Dyer P; University of Greenwich at Medway, Kent, UK., Harbige L; University of Greenwich at Medway, Kent, UK., Deacon A; University of Greenwich at Medway, Kent, UK., Pecorino L; University of Greenwich at Medway, Kent, UK., Getti GTM; University of Greenwich at Medway, Kent, UK.

Publikováno v: The FEBS journal [FEBS J] 2020 May; Vol. 287 (9), pp. 1777-1797. Date of Electronic Publication: 2019 Dec 20.