Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Getman, Daniel P."'
Autor:
Nagarajan, Srinivasan R, De Crescenzo, Gary A, Getman, Daniel P, Lu, Hwang-Fun, Sikorski, James A, Walker, Jeffrey L, McDonald, Joseph J, Houseman, Kathryn A, Kocan, Geralyn P, Kishore, Nandini, Mehta, Pramod P, Funkes-Shippy, Christie L, Blystone, Lisa
Publikováno v:
In Bioorganic & Medicinal Chemistry 2003 11(22):4769-4777
Autor:
Freskos, John N., Mischke, Brent V., DeCrescenzo, Gary A., Heintz, Robert, Getman, Daniel P., Howard, Susan C., Kishore, Nandini N., McDonald, Joseph J., Munie, Grace E., Rangwala, Shaukat, Swearingen, Craig A., Voliva, Charles, Welsch, Dean J.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(7):943-948
Autor:
Srinivasan Nagarajan, Gary Anthony De Crescenzo, James A. Sikorski, Getman Daniel P, Jeffrey L Walker, Lisa Blystone, Christie L Funkes-Shippy, Nandini Kishore, Pramod P. Mehta, Kathryn A Houseman, Geralyn P. Kocan, Hwang Fun Lu, Joseph J. McDonald
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:4769-4777
The human immunodeficiency virus (HIV) has been shown to be the causative agent for AIDS. The HIV virus encodes for a unique aspartyl protease that is essential for the production of enzymes and proteins in the final stages of maturation. Protease in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e41f7ee8ade0e21d88ea525341587f
https://doi.org/10.1016/j.bmc.2003.07.001
https://doi.org/10.1016/j.bmc.2003.07.001
Autor:
Sena Garber, Susan Erickson-Viitanen, Susan Jeffrey, Lee T. Bacheler, Beverly C. Cordova, Joanne Saye, George L. Trainor, Pamela Cawood, Greg D. Harris, Janan Jona, Ronald M. Klabe, Robert F. Kaltenbach, Marc Davies, Getman Daniel P, Sharon Diamond, Kelly Logue
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:3021-3028
Human immunodeficiency virus (HIV) protease inhibitors (PIs) are important components of many highly active antiretroviral therapy regimens. However, development of phenotypic and/or genotypic resistance can occur, including cross-resistance to other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5adec0560a01fd5a81db1eaee844bc5
https://doi.org/10.1128/aac.45.11.3021-3028.2001
https://doi.org/10.1128/aac.45.11.3021-3028.2001
Autor:
Hwang-Fun Lu, James A. Sikorski, Sandra K. Freeman, David L. Brown, Mark E. Zupec, Srinivasan Nagarajan, Getman Daniel P, Balekudru Devadas, Charles A. McWherter
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:379-382
A survey of potential cyclic and acyclic lysine replacements in known l -seryl- l -lysyl dipeptide inhibitors of C. albicans NMT identified the thioether 16 and glycinamide 18 as submicromolar inhibitors of C. albicans NMT, which retained good select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd4b06be4207370103725668ab20214
https://doi.org/10.1016/s0960-894x(97)00030-9
https://doi.org/10.1016/s0960-894x(97)00030-9
Autor:
Geralyn P. Kocan, Heintz Robert M, Getman Daniel P, Deborah E. Bertenshaw, Mischke Brent, Christine Funckes-Shippy, Lisa W. Blystone, Martin L. Bryant, Nandini Kishore, Pramod P. Mehta, Kathyrn A. Houseman, John N. Freskos
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:445-450
We have discovered a potent low molecular weight series of HIV-1 Protease inhibitors incorporating the (R)-(hydroxyethyl) sulfonamide isostere.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261cd57af1b9ecc6c62f077147805e42
https://doi.org/10.1016/0960-894x(96)00035-2
https://doi.org/10.1016/0960-894x(96)00035-2
Autor:
Decrescenzo Gary A, J Marr, Mary Smidt, R Dillard, Heintz Robert M, Getman Daniel P, D Lansky, K Houseman, Michael Clare, Martin L. Bryant
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:2229-2234
SC-52151 is a potent, selective, tight-binding human immunodeficiency virus (HIV) protease inhibitor containing the novel (R)-(hydroxyethyl) urea isostere. The mean 50% effective concentration for lymphotropic, monocytotropic strains and field isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de628e860149087b8946c4f14905e95
https://doi.org/10.1128/aac.39.10.2229
https://doi.org/10.1128/aac.39.10.2229
Autor:
Shashidhar N. Rao, Francis J. Koszyk, Ish K. Khanna, Decrescenzo Gary A, Getman Daniel P, Janet Anne Julien, Richard M. Weier, Stealey Michael A, Heintz Robert M, Richard A. Mueller, Lydia Swenton
Publikováno v:
Journal of Carbohydrate Chemistry. 14:843-878
A useful methodology for the synthesis of a number of 2-, 3- and 2,3-disubstituted deoxynojirimycin analogs is reported. It has been found that the epoxides in stereoselectively synthesized N-carboalkoxy-2,3-anhydro-1-deoxymannojirimycins (4 and 5) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97befdaa53d580da61e6afa663f24b01
https://doi.org/10.1080/07328309508005380
https://doi.org/10.1080/07328309508005380
Autor:
James A. Sikorski, David L. Brown, Srinivasan Nagarajan, Sandra K. Freeman, Jeffrey I. Gordon, Mark E. Zupec, Balekudru Devadas, Getman Daniel P, Mcwherter Charles A
Publikováno v:
Journal of Medicinal Chemistry. 38:1837-1840
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7da0043f27a4464567135bbb02a738f
https://doi.org/10.1021/jm00011a001
https://doi.org/10.1021/jm00011a001
Autor:
Getman, Daniel P.
The Greater Kansas City region has made significant progress as a national center for animal health and the biosciences. Each of our stakeholder institutions have continued to make significant advances in key programs, which collectively have elevate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::736c3112eab1df9ce70daf8969a21b44
https://europepmc.org/articles/PMC6188302/
https://europepmc.org/articles/PMC6188302/
