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Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.

Autor: Tommelein J; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., De Vlieghere E; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Verset L; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium., Melsens E; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Surgery, Ghent University Hospital, Ghent, Belgium., Leenders J; Center for Interdisciplinary Research on Medicines (CIRM), Université de Liège, Liège, Belgium., Descamps B; Department of Electronics and Information System, iMinds-IBiTech-MEDISIP, Ghent University, Ghent, Belgium., Debucquoy A; Department of Oncology, Experimental Radiotherapy, KU Leuven, University Hospitals Leuven, Leuven, Belgium., Vanhove C; Department of Electronics and Information System, iMinds-IBiTech-MEDISIP, Ghent University, Ghent, Belgium., Pauwels P; Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium., Gespach CP; Institut National de la Santé et de la Recherche Médicale, INSERM U938, Molecular and Clinical Oncology, Université Paris VI Pierre et Marie Curie, Paris, France., Vral A; Department of Basic Medical Sciences, Physiology Group, Ghent University, Ghent, Belgium., De Boeck A; Arnie Charbonneau Cancer Centre, University of Calgary, Calgary, Alberta, Canada., Haustermans K; Department of Oncology, Experimental Radiotherapy, KU Leuven, University Hospitals Leuven, Leuven, Belgium., de Tullio P; Center for Interdisciplinary Research on Medicines (CIRM), Université de Liège, Liège, Belgium., Ceelen W; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Surgery, Ghent University Hospital, Ghent, Belgium., Demetter P; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium., Boterberg T; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Bracke M; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., De Wever O; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium. olivier.dewever@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.

Publikováno v: Cancer research [Cancer Res] 2018 Feb 01; Vol. 78 (3), pp. 659-670. Date of Electronic Publication: 2017 Dec 07.

Activation of adenylyl cyclases, regulation of insulin status, and cell survival by G(alpha)olf in pancreatic beta-cells.

Autor: Régnauld KL; Institut National de la Santé et de la Recherche Médicale U482, Signal Transduction and Cellular Function in Diabetes and Digestive Cancers, Saint-Antoine Hospital, 75571 Paris Cedex 12, France., Leteurtre E, Gutkind SJ, Gespach CP, Emami S

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2002 Mar; Vol. 282 (3), pp. R870-80.