Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.

Autor: Tommelein J; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., De Vlieghere E; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Verset L; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium., Melsens E; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Surgery, Ghent University Hospital, Ghent, Belgium., Leenders J; Center for Interdisciplinary Research on Medicines (CIRM), Université de Liège, Liège, Belgium., Descamps B; Department of Electronics and Information System, iMinds-IBiTech-MEDISIP, Ghent University, Ghent, Belgium., Debucquoy A; Department of Oncology, Experimental Radiotherapy, KU Leuven, University Hospitals Leuven, Leuven, Belgium., Vanhove C; Department of Electronics and Information System, iMinds-IBiTech-MEDISIP, Ghent University, Ghent, Belgium., Pauwels P; Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium., Gespach CP; Institut National de la Santé et de la Recherche Médicale, INSERM U938, Molecular and Clinical Oncology, Université Paris VI Pierre et Marie Curie, Paris, France., Vral A; Department of Basic Medical Sciences, Physiology Group, Ghent University, Ghent, Belgium., De Boeck A; Arnie Charbonneau Cancer Centre, University of Calgary, Calgary, Alberta, Canada., Haustermans K; Department of Oncology, Experimental Radiotherapy, KU Leuven, University Hospitals Leuven, Leuven, Belgium., de Tullio P; Center for Interdisciplinary Research on Medicines (CIRM), Université de Liège, Liège, Belgium., Ceelen W; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Surgery, Ghent University Hospital, Ghent, Belgium., Demetter P; Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium., Boterberg T; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Bracke M; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., De Wever O; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Ghent, Belgium. olivier.dewever@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.

Publikováno v: Cancer research [Cancer Res] 2018 Feb 01; Vol. 78 (3), pp. 659-670. Date of Electronic Publication: 2017 Dec 07.

DCLRE1B promotes tumor progression and predicts immunotherapy response through METTL3-mediated m6A modification in pancreatic cancer.

Autor: Li, Lincheng^1,2 (AUTHOR), Wang, Fei¹ (AUTHOR), Deng, Zhaoda¹ (AUTHOR), Zhang, Gong¹ (AUTHOR), Zhu, Lin¹ (AUTHOR), Zhao, Zhiming¹ (AUTHOR) Zhimingzhao616@126.com, Liu, Rong¹ (AUTHOR) liurong301@126.com

Publikováno v: BMC Cancer. 11/7/2023, Vol. 23 Issue 1, p1-14. 14p.

Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling.

Autor: Lapeire L; Department of Medical Oncology, Ghent University Hospital, Ghent, Belgium., Hendrix A; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium., Lambein K; Department of Pathology, Ghent University Hospital, Ghent, Belgium., Van Bockstal M; Department of Pathology, Ghent University Hospital, Ghent, Belgium., Braems G; Department of Gynaecology, Ghent University Hospital, Ghent, Belgium., Van Den Broecke R; Department of Gynaecology, Ghent University Hospital, Ghent, Belgium., Limame R; Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium., Mestdagh P; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium., Vandesompele J; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium., Vanhove C; Institute Biomedical Technology, Ghent University Hospital, Ghent, Belgium., Maynard D; Medical Genetics Branch, National Human Genome Research Institute, Bethesda, Maryland., Lehuédé C; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, UPS, Toulouse, France., Muller C; Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, UPS, Toulouse, France., Valet P; Institut National de la Santé et de la Recherche Médicale, INSERM U1048, Université Paul Sabatier, Toulouse, France., Gespach CP; Institut National de la Santé et de la Recherche Médicale, INSERM U938, Molecular and Clinical Oncology, Université Paris VI Pierre et Marie Curie, Paris, France., Bracke M; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium., Cocquyt V; Department of Medical Oncology, Ghent University Hospital, Ghent, Belgium., Denys H; Department of Medical Oncology, Ghent University Hospital, Ghent, Belgium., De Wever O; Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium. olivier.dewever@ugent.be.

Publikováno v: Cancer research [Cancer Res] 2014 Dec 01; Vol. 74 (23), pp. 6806-19. Date of Electronic Publication: 2014 Sep 24.

Activation of adenylyl cyclases, regulation of insulin status, and cell survival by G(alpha)olf in pancreatic beta-cells.

Autor: Régnauld KL; Institut National de la Santé et de la Recherche Médicale U482, Signal Transduction and Cellular Function in Diabetes and Digestive Cancers, Saint-Antoine Hospital, 75571 Paris Cedex 12, France., Leteurtre E, Gutkind SJ, Gespach CP, Emami S

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2002 Mar; Vol. 282 (3), pp. R870-80.

Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1.

Autor: McKenna P; Pharmaceutical Sciences Institute, Aston University, Birmingham., Williams JM, Gespach CP, Hanson PJ

Publikováno v: Gut [Gut] 1993 Jul; Vol. 34 (7), pp. 953-7.