Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites

Autor: Gesine Kaiser, Mariana De Niz, Paul-Christian Burda, Livia Niklaus, Rebecca Limenitakis Stanway, Volker Heussler

Publikováno v: Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017)

Abstract Background Malaria research is greatly dependent on and has drastically advanced with the possibility of genetically modifying Plasmodium parasites. The commonly used transfection protocol by Janse and colleagues utilizes blood stage-derived

Externí odkaz: https://doaj.org/article/1412f7e29f2d4795a270998e2d705e0f

Hijacking of the host cell Golgi by Plasmodium berghei liver stage parasites

Autor: Volker Heussler, Mariana De Niz, Gesine Kaiser, Won Do Heo, Reto Caldelari, Benoît Zuber, Carolina Agop-Nersesian

Publikováno v: Journal of Cell Science
article-version (VoR) Version of Record
De Niz, Mariana; Caldelari, Reto; Kaiser, Gesine; Zuber, Benoît; Heo, Won Do; Heussler, Volker T.; Agop-Nersesian, Carolina (2021). Hijacking of the host cell Golgi by Plasmodium berghei liver stage parasites. Journal of cell science, 134(10) Company of Biologists Limited 10.1242/jcs.252213

The intracellular lifestyle represents a challenge for the rapidly proliferating liver stage Plasmodium parasite. In order to scavenge host resources, Plasmodium has evolved the ability to target and manipulate host cell organelles. Using dynamic flu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62443702230a8cbccdf91d6506ba9dc1

Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development

Autor: Judith L. Green, Declan Brady, Asif Mohmmed, Rajan Pandey, Gesine Kaiser, Ludek Koreny, David S. Guttery, Mohammad Zeeshan, Rebecca Limenitakis, Ross F. Waller, Pawan Malhotra, Shreyansh Tatiya, Anthony A. Holder, Andrew R. Bottrill, Vandana Thakur, Ekta Saini, Inderjeet Kaur, Volker Heussler, Rita Tewari, Nicholas J. Katris, Pradeep Kumar

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Saini, Ekta; Zeeshan, Mohammad; Brady, Declan; Pandey, Rajan; Kaiser, Gesine; Koreny, Ludek; Kumar, Pradeep; Thakur, Vandana; Tatiya, Shreyansh; Katris, Nicholas J; Limenitakis Stanway, Rebecca; Kaur, Inderjeet; Green, Judith L; Bottrill, Andrew R; Guttery, David S; Waller, Ross F; Heussler, Volker; Holder, Anthony A; Mohmmed, Asif; Malhotra, Pawan; ... (2017). Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development. Scientific Reports, 7(1), p. 15577. Nature Publishing Group 10.1038/s41598-017-15781-z
Scientific Reports

Plasmodium parasites, the causative agents of malaria, possess a distinctive membranous structure of flattened alveolar vesicles supported by a proteinaceous network, and referred to as the inner membrane complex (IMC). The IMC has a role in actomyos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d9e2c3b2e90734575458bb87fff040
http://link.springer.com/article/10.1038/s41598-017-15781-z

Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites

Autor: Livia Niklaus, Rebecca Limenitakis Stanway, Gesine Kaiser, Paul-Christian Burda, Volker Heussler, Mariana De Niz

Publikováno v: Malaria Journal
Kaiser, Gesine; De Niz Hidalgo, Mariana Isabel; Burda, Paul-Christian; Niklaus, Livia; Limenitakis Stanway, Rebecca; Heussler, Volker (2017). Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites. Malaria journal, 16(1), p. 305. BioMed Central 10.1186/s12936-017-1949-y
Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017)

Background Malaria research is greatly dependent on and has drastically advanced with the possibility of genetically modifying Plasmodium parasites. The commonly used transfection protocol by Janse and colleagues utilizes blood stage-derived Plasmodi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6dbcf02425e0b1be008846a386404f
https://pubmed.ncbi.nlm.nih.gov/28764716

Progress in imaging methods: insights gained into Plasmodium biology

Autor: Gesine Kaiser, Paul-Christian Burda, Volker Heussler, Mariana De Niz, Tobias Spielmann, Freddy Frischknecht, Hernando A. del Portillo

Publikováno v: Nature reviews. Microbiology

Over the past decade, major advances in imaging techniques have enhanced our understanding of Plasmodium spp. parasites and their interplay with mammalian hosts and mosquito vectors. Cryoelectron tomography, cryo-X-ray tomography and super-resolution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2c740d4c53907559c74a5bb4951b19
https://pubmed.ncbi.nlm.nih.gov/27890922