Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gesine Heuck"'
Publikováno v:
Journal of Drug Targeting. 24:821-835
Microfluidic devices are mircoscale fluidic circuits used to manipulate liquids at the nanoliter scale. The ability to control the mixing of fluids and the continuous nature of the process make it apt for solvent/antisolvent precipitation of drug-del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afe110aab1d36b49a257b28f0ae496e
https://doi.org/10.1080/1061186x.2016.1198354
https://doi.org/10.1080/1061186x.2016.1198354
Autor:
J. R. Mellin, Gesine Heuck, Evelyne Turlin, Cécile Wandersman, Norbert Lange, Noémie Szili, Maria Inês Simões Brandão
Publikováno v:
MicrobiologyOpen
In most organisms, heme biosynthesis is strictly controlled so as to avoid heme and heme precursor accumulation, which is toxic. Escherichia coli regulates heme biosynthesis by a feedback loop involving heme-induced proteolytic cleavage of HemA, glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cfc6637f1fdda02b932ae29ef3ea9d
https://doi.org/10.1002/mbo3.203
https://doi.org/10.1002/mbo3.203
Autor:
Norbert Lange, Gesine Heuck
Publikováno v:
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
The hexyl ester of 5-aminolevulinic acid (HAL) is an efficient inducer of the endogenous photosensitizer protoporphyrin IX (PPIX) in neoplastic tissue and approved for the fluorescence photodetection of bladder cancer. It is, however, limited to topi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b40eb2dea22a22e9323ff56fdf95bc4
https://doi.org/10.1142/s1088424612500873
https://doi.org/10.1142/s1088424612500873
Autor:
Norbert Lange, Gesine Heuck
Publikováno v:
Photosensitizers in Medicine, Environment, and Security ISBN: 9789048138708
The photosensitizing properties of endogenous porphyrins have been discovered about 100 years ago. Since then they have become an attractive means to detect and treat neoplastic tissue by fluorescence photodetection (PD) and photodynamic therapy (PDT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::debf450755982000ee86c199b036b566
https://doi.org/10.1007/978-90-481-3872-2_8
https://doi.org/10.1007/978-90-481-3872-2_8
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 106, No 28 (2009) pp. 11719-24
Because heme is a major iron-containing molecule in vertebrates, the ability to use heme-bound iron is a determining factor in successful infection by bacterial pathogens. Until today, all known enzymes performing iron extraction from heme did so thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dfab955327105bf6d021ae05c4f65a
https://pubmed.ncbi.nlm.nih.gov/19564607
https://pubmed.ncbi.nlm.nih.gov/19564607