Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Gesine Hansen"'
Autor:
Mania Ackermann, Fawaz Saleh, Shifaa M. Abdin, Anna Rafiei Hashtchin, Ingrid Gensch, Julia Golgath, Marco Carvalho Oliveira, Ariane H. H. Nguyen, Svenja Gaedcke, Arno Fenske, Mi-Sun Jang, Adan C. Jirmo, Markus Abeln, Gesine Hansen, Nico Lachmann
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background There is a significant demand for intermediate-scale bioreactors in academic and industrial institutions to produce cells for various applications in drug screening and/or cell therapy. However, the application of these bioreactor
Externí odkaz:
https://doaj.org/article/a386a9eed5a141dcb1f49f98b94c1d5f
Autor:
Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infection in infants, older adults and the immunocompromised. Effective directly acting antivirals are not yet available for clinical use. To address this,
Externí odkaz:
https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4
Autor:
Ivan Odak, Lennart Riemann, Inga Sandrock, Anne Cossmann, Gema Morillas Ramos, Swantje I. Hammerschmidt, Christiane Ritter, Michaela Friedrichsen, Ahmed Hassan, Alexandra Dopfer-Jablonka, Metodi V. Stankov, Leonie M. Weskamm, Marylyn M. Addo, Inga Ravens, Stefanie Willenzon, Anja Schimrock, Jasmin Ristenpart, Anika Janssen, Joana Barros-Martins, Gesine Hansen, Christine Falk, Georg M.N. Behrens, Reinhold Förster
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104947- (2024)
Summary: Background: Human immune responses to COVID-19 vaccines display a large heterogeneity of induced immunity and the underlying immune mechanisms for this remain largely unknown. Methods: Using a systems biology approach, we longitudinally prof
Externí odkaz:
https://doaj.org/article/dc942db6e492430cafa301d2bcc525b7
Autor:
Gesine Hansen, Axel Schambach, Christine S Falk, Arnold Kloos, Michael Morgan, Shifaa M. Abdin, Daniela Paasch, Nico Lachmann, Marco Carvalho Oliveira, Mi-Sun Jang, Mania Ackermann, Andriana Stamopoulou, Philipp J Mroch, Constantin S von Kaisenberg, Michael Heuser, Thomas Moritz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Macrophages have recently become attractive therapeutics in cancer immunotherapy. The potential of macrophages to infiltrate and influence solid malignancies makes them promising targets for the chimeric antigen receptor (CAR) technology t
Externí odkaz:
https://doaj.org/article/95887552adbe4426b971a8b340ad3b4a
Autor:
Jessica Rademacher, Luise Martin, Anja Theloe, Mirjam Stahl, Marcus A. Mall, Oana Joean, Jan Fuge, Gesine Hansen, Tobias Welte, Katharina Schütz, Felix C. Ringshausen, Anna M. Dittrich
Publikováno v:
ERJ Open Research, Vol 9, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/1db4ca9ebe8f422c99e791faf3d014c2
Autor:
Katharina Schütz, Sophia Theres Pallenberg, Julia Kontsendorn, David DeLuca, Cinja Sukdolak, Rebecca Minso, Tina Büttner, Martin Wetzke, Christian Dopfer, Annette Sauer-Heilborn, Felix C. Ringshausen, Sibylle Junge, Burkhard Tümmler, Gesine Hansen, Anna-Maria Dittrich
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Triple-combination cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy with elexacaftor/tezacaftor/ivacaftor (ETI) was introduced in August 2020 in Germany for people with CF (pwCF) ≥12 years (yrs.) of age and
Externí odkaz:
https://doaj.org/article/13a47554be204fd0998da41883ff5b1f
Autor:
Anna-Lisa Sorg, Leon Bergfeld, Marietta Jank, Victor Corman, Ilia Semmler, Anna Goertz, Andreas Beyerlein, Eva Verjans, Norbert Wagner, Horst Von Bernuth, Fabian Lander, Katharina Weil, Markus Hufnagel, Ute Spiekerkoetter, Cho-Ming Chao, Lutz Naehrlich, Ania Carolina Muntau, Ulf Schulze-Sturm, Gesine Hansen, Martin Wetzke, Anna-Maria Jung, Tim Niehues, Susanne Fricke-Otto, Ulrich Von Both, Johannes Huebner, Uta Behrends, Johannes G. Liese, Christian Schwerk, Christian Drosten, Ruediger Von Kries, Horst Schroten
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Children are less likely to be infected with SARS-CoV-2 and develop less severe disease than adults, which makes estimation of infection rates challenging. Here, the authors conduct seroprevalence surveys of children in Germany, describe changes in p
Externí odkaz:
https://doaj.org/article/155b66c56a5d4cee8aa6492ffb7809ef
Autor:
Adan Chari Jirmo, Ruth Grychtol, Svenja Gaedcke, Bin Liu, Stephanie DeStefano, Christine Happle, Olga Halle, Joao T. Monteiro, Anika Habener, Oliver D. Breiholz, David DeLuca, Gesine Hansen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
A single population of interferon-regulatory factor 8 (Irf8)-dependent conventional dendritic cell (cDC type1) is considered to be responsible for both immunogenic and tolerogenic responses depending on the surrounding cytokine milieu. Here, we chall
Externí odkaz:
https://doaj.org/article/905d4a535d9f4546a1c6926af1257efd
Autor:
Martin Wetzke, Katharina Schütz, Matthias Volkmar Kopp, Jürgen Seidenberg, Christian Vogelberg, Tobias Ankermann, Christine Happle, Gesche Voigt, Holger Köster, Thomas Illig, Christiane Lex, Antje Schuster, Ralph Maier, Marcus Panning, Grit Barten, Gernot Rohde, Tobias Welte, Gesine Hansen
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Paediatric community-acquired pneumonia (CAP) is a leading cause of paediatric morbidity. However, particularly for outpatients with paediatric CAP, data on aetiology and management are scarce. Methods The prospective pedCAPNETZ study mult
Externí odkaz:
https://doaj.org/article/9fa7d83f75914a4f84d8717ae3504d9b
Autor:
Sophia T. Pallenberg, Inka Held, Christian Dopfer, Rebecca Minso, Manuel M. Nietert, Gesine Hansen, Burkhard Tümmler, Anna-Maria Dittrich
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Evidence for the efficiency of highly-effective triple-CFTR-modulatory therapy with elexacaftor/tezacaftor/ivacaftor (ETI), either demonstrated in clinical trials or by in vitro testing, is lacking for about 10% of people with cystic fi
Externí odkaz:
https://doaj.org/article/ab861ae3419c4534839b69562c2257bf