Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gesa Rickheit"'
Endosomal Chloride-Proton Exchange Rather Than Chloride Conductance Is Crucial for Renal Endocytosis
Publikováno v:
Science. 328:1398-1401
Chloride Balancing Act The ionic composition of the cytosol and intracellular organelles must be regulated in the face of ongoing membrane traffic into and out of the cell. Now, two papers address the consequences of a change in the transport phenoty
Endocochlear potential depends on Cl− channels: mechanism underlying deafness in Bartter syndrome IV
Autor:
Thomas J. Jentsch, Nicola Strenzke, Hannes Maier, Adrian Muenscher, Corina E. Andreescu, Gesa Rickheit, Chris I. De Zeeuw, Anselm A. Zdebik
Publikováno v:
The EMBO journal, 27(21): 2809-2942
Human Bartter syndrome IV is an autosomal recessive disorder characterized by congenital deafness and severe renal salt and fluid loss. It is caused by mutations in BSND, which encodes barttin, a beta-subunit of ClC-Ka and ClC-Kb chloride channels. I
Publikováno v:
Pflugers Archiv : European journal of physiology. 458(1)
The CLC gene family encodes Cl(-) channels or Cl(-)/H(+) exchangers. While our understanding of their structure-function relationship has greatly benefited from the crystal structure of bacterial homologues, human inherited diseases and knock-out mic
Autor:
Fabio Mammano, Saida Ortolano, Stephen D. Roper, Fabio Anselmi, William D. Richardson, Mikhail A. Filippov, Giulia Crispino, Anke Seydel, Victor H. Hernandez, Nicoletta Kessaris, Hannah Monyer, Gesa Rickheit
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 105(48): 18770–18775
Extracellular ATP controls various signaling systems including propagation of intercellular Ca 2+ signals (ICS). Connexin hemichannels, P2x7 receptors (P2x7Rs), pannexin channels, anion channels, vesicles, and transporters are putative conduits for A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e51c14ddf518e4fa90ebec74e57afb
http://hdl.handle.net/11577/2267457
http://hdl.handle.net/11577/2267457
Publikováno v:
Kidney international. 70(1)
Mutations in ClC-5 cause Dent's disease, a disorder associated with low molecular weight proteinuria, hyperphosphaturia, and kidney stones. ClC-5 is a Cl(-)/H(+)-exchanger predominantly expressed in the kidney, where it facilitates the acidification