Synthesis of Hybrid Polyphenol/Hydroxyapatite Nanomaterials with Anti-Radical Properties

Autor: Estelle Palierse, Sylvie Masse, Guillaume Laurent, Patrick Le Griel, Gervaise Mosser, Thibaud Coradin, Claude Jolivalt

Publikováno v: Nanomaterials, Vol 12, Iss 20, p 3588 (2022)

Plant-derived natural bioactive molecules are of great therapeutic potential but, so far, their application in nanomedicine has scarcely been studied. This work aimed at comparing two methodologies, i.e., adsorption and in situ incorporation, to prep

Externí odkaz: https://doaj.org/article/a9beb80dde3a435fa26e2000cd8565c7

Porous yet dense matrices: using ice to shape collagen 3D cell culture systems with increased physiological relevance

Autor: Cleo Parisi, Bénédicte Thiébot, Gervaise Mosser, Léa Trichet, Philippe Manivet, Francisco M. Fernandes

Publikováno v: Biomaterials Science
Biomaterials Science, 2022, 10 (24), pp.6939-6950. ⟨10.1039/d2bm00313a⟩

Standardin vitrocell culture is one of the pillars of biomedical science. However, there is increasing evidence that 2D systems provide biological responses that are often in disagreement within vivoobservations, partially due to limitations in repro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44091170f38bd224d2d73936d8e20c8
https://doi.org/10.1039/d2bm00313a

Circular-dichroism SHG microscopy probes the polarity distribution of out-of-plane collagen fibril assemblies

Autor: Maged Alnawaiseh, Uwe Hansen, François Légaré, Maxime Pinsard, Gervaise Mosser, Vincent Borderie, Marie-Claire Schanne-Klein, Claire Teulon, Gaël Latour, Carole Aimé, Djida Ghoubay, Margaux Schmeltz

Publikováno v: 2021 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC).

Second harmonic generation microscopy (SHG) is now the gold standard technique for in situ visualization of unstained fibrillar collagen in intact tissues [1] . Collagen is the most abundant protein in mammals and is found in many tissues, such as ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d53eaa45fd5beb26b58ffc7f53886303
https://doi.org/10.1109/cleo/europe-eqec52157.2021.9541748

Core–Shell Pure Collagen Threads Extruded from Highly Concentrated Solutions Promote Colonization and Differentiation of C3H10T1/2 Cells

Autor: Delphine Duprez, Léa Trichet, Bernard Haye, Olivier Ronsin, Guillaume Ducourthial, Gervaise Mosser, Marie-Claire Schanne-Klein, Lise Picaut, Tristan Baumberger, Christophe Hélary, Marie-Ange Bonnin

Publikováno v: ACS Biomaterials Science and Engineering
ACS Biomaterials Science and Engineering, ACS, 2021, ⟨10.1021/acsbiomaterials.0c01273⟩
ACS Biomaterials Science and Engineering, 2021, ⟨10.1021/acsbiomaterials.0c01273⟩

International audience; The elaboration of scaffolds able to efficiently promote cell differentiation toward a given cell type remains challenging. Here, we engineered dense type I collagen threads with the aim of providing scaffolds with specific mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3a37f16c6d36a0338b7f551e60b4e8
https://hal.archives-ouvertes.fr/hal-03113880

Thrombin-free polymerization leads to pure fibrin(ogen) materials with extended processing capacity

Autor: Thibaud Coradin, Léa Trichet, Bernard Haye, Nicolas Sanson, Gervaise Mosser, Clément Rieu

Fibrin is a key protein for various clinical applications such as tissue reconstruction. However, in contrast to type I collagen, fibrin shaping has so far faced major limitations related to the necessity to add thrombin enzyme to fibrinogen precurso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a18cafee6c6ec379380c773b16832c
https://hal.archives-ouvertes.fr/hal-03085797/file/2020.05.12.091793.full.pdf