Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gerusa Duarte Dalmolin"'
Autor:
Guilherme Monteiro Gomes, Gerusa Duarte Dalmolin, Julia Bär, Anna Karpova, Carlos Fernando Mello, Michael R Kreutz, Maribel Antonello Rubin
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99184 (2014)
In Alzheimer's disease (AD), the β-amyloid peptide (Aβ) has been causally linked to synaptic dysfunction and cognitive impairment. Several studies have shown that N-Methyl-D-Aspartate receptors (NMDAR) activation is involved in the detrimental acti
Externí odkaz:
https://doaj.org/article/7ade748fbcf446b387cb49c9ae9c3376
Autor:
Camila Gewehr, Sara Marchesan Oliveira, Mateus Fortes Rossato, Gabriela Trevisan, Gerusa Duarte Dalmolin, Flávia Karine Rigo, Célio José de Castro Júnior, Marta Nascimento Cordeiro, Juliano Ferreira, Marcus V Gomez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 4, p e2198 (2013)
BackgroundThe frequency of accidental spider bites in Brazil is growing, and poisoning due to bites from the spider genus Phoneutria nigriventer is the second most frequent source of such accidents. Intense local pain is the major symptom reported af
Externí odkaz:
https://doaj.org/article/9a26dc828585472daf373b5d4952077a
Autor:
Gerusa Duarte Dalmolin
Publikováno v:
Biblioteca Digital de Teses e Dissertações da UFMGUniversidade Federal de Minas GeraisUFMG.
Venom peptides have produced exceptional lead compouds for drug development to treat pain. In the present study, we examined the antinociceptive and motor effects of Tx3-3, a peptide toxin isolated from Phoneutria nigriventer venom, which inhibit hig
Externí odkaz:
http://hdl.handle.net/1843/BUOS-8GJKK2
Autor:
Maribel Antonello Rubin, Juliano Ferreira, Guilherme M. Gomes, Gerusa Duarte Dalmolin, Marcus Vinicius Gomez, Marta N. Cordeiro
Publikováno v:
Toxicon. 76:23-27
Potassium channels regulate many neuronal functions, including neuronal excitability and synaptic plasticity, contributing, by these means, to mnemonic processes. In particular, A-type K+ currents (IA) play a key role in hippocampal synaptic plastici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f589901ca4aa57d220fd4bd7218994
Autor:
Célio José de Castro Junior, Gerusa Duarte Dalmolin, Juliano Ferreira, Marcus Vinicius Gomez, Flávia Karine Rigo, Michael K. Richardson, Marta N. Cordeiro, Gabriela Trevisan, Fernanda A. Rosa, Marco Aurélio Romano-Silva, Michel Fleith Otuki, Ana Paula Cueto
Publikováno v:
Cancer Sci
The marine snail peptide ziconotide (ω-conotoxin MVIIA) is used as an analgesic in cancer patients refractory to opioids, but may induce severe adverse effects. Animal venoms represent a rich source of novel drugs, so we investigated the analgesic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0e05a87f60937d46c9034aef813688
https://doi.org/10.1111/cas.12209
https://doi.org/10.1111/cas.12209
Autor:
Mateus Rossato, Lidia La Rocca Tamiozzo, Sara Marchesan Oliveira, Gabriela Trevisan, Juliano Ferreira, Raquel Tonello, Daniela Almeida Cabrini, Cássia Regina Silva, Indiara Brusco, Camila de Campos Velho Gewehr, Marcus Vinicius Gomez, Flávia Karine Rigo, Gerusa Duarte Dalmolin
Publikováno v:
Molecular neurobiology. 54(10)
Paclitaxel is a chemotherapeutic agent used to treat solid tumours. However, it causes an acute and neuropathic pain syndrome that limits its use. Among the mechanisms involved in neuropathic pain caused by paclitaxel is activation of kinin receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60ec5baee20182a8a7c28b3caf686e2
https://pubmed.ncbi.nlm.nih.gov/27844290
https://pubmed.ncbi.nlm.nih.gov/27844290
Autor:
Juliano Ferreira, Marcos A. P. Martins, Maribel Antonello Rubin, Rogerio V. Lourega, Cleber A. Cechinel, Sara Marchesan Oliveira, Helio G. Bonacorso, Alexandre P. Wentz, Nilo Zanatta, Gerusa Duarte Dalmolin, Ronan C. Sehnem, Camila de Campos Velho Gewehr
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 104:122-129
Pain is the most common complaint in the medical field and the identification of compounds that can effectively treat painful states without induction of side-effects remains a major challenge in biomedical research. The aim of the present study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea7e13ff4dd38a38dddb7ce8ad32e5d
https://doi.org/10.1111/j.1742-7843.2008.00353.x
https://doi.org/10.1111/j.1742-7843.2008.00353.x
Autor:
Gerusa Duarte Dalmolin, Carlos Fernando Mello, Nádia Aléssio Velloso, V.D.G. Sinhorin, Graciela Fonini, Maribel Antonello Rubin, Aron Ferreira da Silveira
Publikováno v:
Brain Research. 1198:107-114
Polyamines are aliphatic amines containing nucleophilic centers that are found in all eukaryotic cells, including brain cells. These compounds determine neuroprotection in experimental models of cerebral ischemia and neurotoxicity. In the current stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802e3f0d3afa746129ca9792bae7ae3a
https://doi.org/10.1016/j.brainres.2007.12.056
https://doi.org/10.1016/j.brainres.2007.12.056
Autor:
João B. Calixto, Cássia Regina Silva, Juliano Ferreira, Gerusa Duarte Dalmolin, N.A.V. Bellé, Carlos Fernando Mello, Maribel Antonello Rubin
Publikováno v:
Neuropeptides. 41:263-270
Bradykinin is one of the most potent endogenous algesic substances and its role in pain transmission has been intensively studied in the periphery. However, the action of this peptide in central structures involved in pain transmission remains unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d464bbab0476d0362aaf0d7b3b24e23
https://doi.org/10.1016/j.npep.2006.12.007
https://doi.org/10.1016/j.npep.2006.12.007
Autor:
Graciela Fonini, Gerusa Duarte Dalmolin, Nádia Aléssio Velloso Bellé, Maribel Antonello Rubin, João Rocha
Publikováno v:
Brain Research. 1008:245-251
Polyamines, among other functions, are considered to act as a free radical scavenger and antioxidant. The quinolinic acid (QA), sodium nitroprusside (SNP) and iron (Fe +2 ) stimulate production of free radicals and lipid peroxidation. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2877bb7b93980393f2c83fd2e9c89043
https://doi.org/10.1016/j.brainres.2004.02.036
https://doi.org/10.1016/j.brainres.2004.02.036