Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Gertrud Schmitt"'
Autor:
Jagadeesh K. Venkatesan, Janina Frisch, Ana Rey-Rico, Gertrud Schmitt, Henning Madry, Magali Cucchiarini
Publikováno v:
Journal of Experimental Orthopaedics, Vol 4, Iss 1, Pp 1-13 (2017)
Abstract Background Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments for articular cartila
Externí odkaz:
https://doaj.org/article/2cd077524df04c79a6942220548c9f8a
Autor:
Weikun Meng, Ana Rey-Rico, Mickaël Claudel, Gertrud Schmitt, Susanne Speicher-Mentges, Françoise Pons, Luc Lebeau, Jagadeesh K. Venkatesan, Magali Cucchiarini
Publikováno v:
Nanomaterials, Vol 10, Iss 5, p 855 (2020)
Scaffold-assisted gene therapy is a highly promising tool to treat articular cartilage lesions upon direct delivery of chondrogenic candidate sequences. The goal of this study was to examine the feasibility and benefits of providing highly chondrorep
Externí odkaz:
https://doaj.org/article/237310a22faf4964890d90622f337fce
Autor:
Jagadeesh K. Venkatesan, Weikun Meng, Ana Rey-Rico, Gertrud Schmitt, Susanne Speicher-Mentges, Céline Falentin-Daudré, Amélie Leroux, Henning Madry, Véronique Migonney, Magali Cucchiarini
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 280 (2020)
Background: The delivery of therapeutic genes in sites of articular cartilage lesions using non-invasive, scaffold-guided gene therapy procedures is a promising approach to stimulate cartilage repair while protecting the cargos from detrimental immun
Externí odkaz:
https://doaj.org/article/ba2b701ca7614da384637281e02ad022
Autor:
Janina Frisch, Jagadeesh K. Venkatesan, Ana Rey‐Rico, Adam M. Zawada, Gertrud Schmitt, Henning Madry, Magali Cucchiarini
Publikováno v:
Journal of Experimental Orthopaedics, Vol 3, Iss 1, Pp n/a-n/a (2016)
Abstract Background Application of genetically modified bone marrow concentrates in articular cartilage lesions is a promising approach to enhance cartilage repair by stimulating the chondrogenic differentiation processes in sites of injury. Method I
Externí odkaz:
https://doaj.org/article/d709afaa0d3b4fb19ac4ea47f437224b
Autor:
Henning Madry, Jagadeesh K. Venkatesan, Gertrud Schmitt, Sarah Schetting, Myriam Ekici, Dieter Kohn, Magali Cucchiarini
Publikováno v:
Sarcoma, Vol 2012 (2012)
Treatment of chondrosarcoma remains a major challenge in orthopaedic oncology. Gene transfer strategies based on recombinant adenoassociated viral (rAAV) vectors may provide powerful tools to develop new, efficient therapeutic options against these t
Externí odkaz:
https://doaj.org/article/3868c1092399488cbf6db941f39bac66
Autor:
Xiaoyu Cai, Jagadeesh K Venkatesan, Gertrud Schmitt, Bashar Reda, Magali Cucchiarini, Matthias Hannig, Henning Madry
Objectives Antimicrobial mouthwashes are recommended as a preventive measure against SARS-Cov-2. This study compared the cytotoxicity of octenidine dihydrochloride and chlorhexidine gluconate at different concentrations on human chondrocytes and cart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de5c7e9141ec1397dcc89f1cb52454c8
https://doi.org/10.21203/rs.3.rs-2628334/v1
https://doi.org/10.21203/rs.3.rs-2628334/v1
Autor:
David Zurakowski, Henning Madry, Jagadeesh K. Venkatesan, Gertrud Schmitt, Cliff Lange, Magali Cucchiarini, Michael D. Menger, Matthias W. Laschke, Susanne Speicher-Mentges
Publikováno v:
The American Journal of Sports Medicine. 49:3696-3707
Background: Gene transfer of the transcription factor SOX9 with clinically adapted recombinant adeno-associated virus (rAAV) vectors offers a powerful tool to durably enhance the repair process at sites of osteochondral injuries and counteract the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795269609ac72c79a87fe37eb3afbd5d
https://doi.org/10.1177/03635465211049414
https://doi.org/10.1177/03635465211049414
Autor:
Jagadeesh K, Venkatesan, Gertrud, Schmitt, Susanne, Speicher-Mentges, Patrick, Orth, Henning, Madry, Magali, Cucchiarini
Publikováno v:
Human gene therapy. 33(17-18)
Implantation of genetically modified chondrogenically competent human bone marrow-derived mesenchymal stromal cells (hMSCs) is an attractive strategy to improve cartilage repair. The goal of this study was to examine the potential benefits of transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0cc67f1bbbde60d7e1ce3f602f2286a
https://pubmed.ncbi.nlm.nih.gov/35722904
https://pubmed.ncbi.nlm.nih.gov/35722904
Autor:
Gertrud Schmitt, Michael D. Menger, Yannik P. Morscheid, Magali Cucchiarini, Matthias W. Laschke, Susanne Speicher-Mentges, Henning Madry, David Zurakowski, Patrick Orth, Jagadeesh K. Venkatesan
Publikováno v:
The American Journal of Sports Medicine. 49:958-969
Background: Osteochondral defects, if left untreated, do not heal and can potentially progress toward osteoarthritis. Direct gene transfer of basic fibroblast growth factor 2 (FGF-2) with the clinically adapted recombinant adeno-associated viral (rAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937953d6f7b578c2eaa426ca8873c66f
https://doi.org/10.1177/0363546521988941
https://doi.org/10.1177/0363546521988941
Autor:
Tamás Oláh, Jan Reinhard, Matthias W. Laschke, Lars K. H. Goebel, Frédéric Walter, Gertrud Schmitt, Susanne Speicher-Mentges, Michael D. Menger, Magali Cucchiarini, Dietrich Pape, Henning Madry
Publikováno v:
Science translational medicine. 14(629)
Although osteoarthritis (OA), a leading cause of disability, has been associated with joint malalignment, scientific translational evidence for this link is lacking. In a clinical case study, we provide evidence of osteochondral recovery upon unloadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38b25cae97cddad6077a7034278599b
https://pubmed.ncbi.nlm.nih.gov/35080913
https://pubmed.ncbi.nlm.nih.gov/35080913