Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Gertjan, Wolbink"'
Autor:
Sander W Tas, Joep Killestein, Joost Raaphorst, Taco W Kuijpers, Alexandre E Voskuyl, Gertjan Wolbink, Theo Rispens, Anneke J van der Kooi, Anja Ten Brinke, Karina de Leeuw, Abraham Rutgers, Juan J Garcia-Vallejo, Frederike J Bemelman, YK Onno Teng, Phyllis I Spuls, Mark Löwenberg, Jelle de Wit, Diane van der Woude, Marcel W Bekkenk, Luuk Wieske, Esther Brusse, Laura Boekel, Filip Eftimov, Eileen W Stalman, Maurice Steenhuis, Sofie Keijzer, Olvi Cristianawati, Koos P J van Dam, Adriaan G Volkers, Annelie H Musters, Nicoline F Post, Angela L Bosma, Marc L Hilhorst, Yosta Vegting, Bo Broens, Barbara Horváth, Annabel M Ruiter, Matthias H Busch, Dirk Jan Hijnen, Niels J M Verstegen, Pieter A van Doorn, Jan JGM Verschuuren, Laura Y L Kummer, Ruth R Hagen, Christine Kreher, Lisan H Kuijper, Mariël C Duurland, Veronique A L Konijn, Carolien E van de Sandt, Laura Fernández Blanco, Amélie Bos, Charlotte Menage, Tineke Jorritsma, Jet van den Dijssel, Rivka de Jongh, Tom Ashhurst, Marit J van Gils, Mathieu Claireaux, Sija Marieke van Ham, Renée CF van Allaart, Adája E Baars, George Elias, Cécile ACM van Els, H Stephan Goedee, Geert RAM D’Haens, Papay BP Jallah, Elham S Mirfazeli, Jim BD Keijser, Lotte van Ouwerkerk, Pieter van Paassen, Agner R Parra Sanchez, W Ludo van der Pol, Corine RG Schreurs, R Bart Takkenberg, Koos AH Zwinderman
Publikováno v:
RMD Open, Vol 10, Iss 4 (2024)
Objectives Methotrexate (MTX) is one of the most commonly used medications to treat rheumatoid arthritis (RA). However, the effect of MTX treatment on cellular immune responses remains incompletely understood. This raises concerns about the vulnerabi
Externí odkaz:
https://doaj.org/article/afff65e4600e4deabe9d42545d2637c0
Autor:
Sander W Tas, Michael T Nurmohamed, Gertjan Wolbink, Martijn Gerritsen, Erik H Vogelzang, Laura Boekel, Femke Hooijberg, Yaëlle R Besten, Maureen Leeuw, Sadaf Atiqi, Maurice Steenhuis, Sofie Keijzer, Jim Keijser, Floris C Loeff
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Background During the COVID-19 pandemic, we developed a digital research platform to longitudinally investigate COVID-19-related outcomes in patients with rheumatic diseases and healthy controls. We used home finger-prick testing in order to collect
Externí odkaz:
https://doaj.org/article/ea46065c1bc047e99e8e45a577306560
Autor:
Ishtu Hageman, Femke Mol, Sadaf Atiqi, Vincent Joustra, Hilal Sengul, Peter Henneman, Ingrid Visman, Theodorus Hakvoort, Mike Nurmohamed, Gertjan Wolbink, Evgeni Levin, Andrew Y.F. Li Yim, Geert D’Haens, Wouter J. de Jonge
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and aimsRheumatoid arthritis (RA) patients are currently treated with biological agents mostly aimed at cytokine blockade, such as tumor necrosis factor-alpha (TNFα). Currently, there are no biomarkers to predict therapy response to these
Externí odkaz:
https://doaj.org/article/499f4a55150d46dd8f718dd216142698
Autor:
Luuk Wieske, Laura Y. L. Kummer, Koos P. J. van Dam, Eileen W. Stalman, Anneke J. van der Kooi, Joost Raaphorst, Mark Löwenberg, R. Bart Takkenberg, Adriaan G. Volkers, Geert R. A. M. D’Haens, Sander W. Tas, Phyllis I. Spuls, Marcel W. Bekkenk, Annelie H. Musters, Nicoline F. Post, Angela L. Bosma, Marc L. Hilhorst, Yosta Vegting, Frederike J. Bemelman, Joep Killestein, Zoé L. E. van Kempen, Alexandre E. Voskuyl, Bo Broens, Agner Parra Sanchez, Gertjan Wolbink, Laura Boekel, Abraham Rutgers, Karina de Leeuw, Barbara Horváth, Jan J. G. M. Verschuuren, Annabel M. Ruiter, Lotte van Ouwerkerk, Diane van der Woude, Cornelia F. Allaart, Y. K. Onno Teng, Pieter van Paassen, Matthias H. Busch, B. Papay Jallah, Esther Brusse, Pieter A. van Doorn, Adája E. Baars, Dirkjan Hijnen, Corine R. G. Schreurs, W. Ludo van der Pol, H. Stephan Goedee, Maurice Steenhuis, Theo Rispens, Anja ten Brinke, Niels J. M. Verstegen, Koos A. H. Zwinderman, S. Marieke van Ham, Taco W. Kuijpers, Filip Eftimov, on behalf of the T2B! immunity against SARS-CoV-2 study group
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-6 (2022)
Abstract Background Studies have suggested incremental short-term adverse events (AE) after repeated vaccination. In this report, we assessed occurrence and risk factors for short-term AEs following repeated SARS-CoV-2 vaccination in patients with va
Externí odkaz:
https://doaj.org/article/67db8621c3964b7a9443d09b66e09e5f
Autor:
Fenna de Vries, Adrianus A. J. Smit, Gertjan Wolbink, Annick de Vries, Floris C. Loeff, Eric J. F. Franssen
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundPembrolizumab is a well-tolerated biologic agent with a potentially stable and durable anti-tumor response. Unfortunately, discontinuation of therapy can occur as a consequence of immune-related adverse effects (irAEs). These irAEs appear i
Externí odkaz:
https://doaj.org/article/80f9f5ef5d7443cb95508f45902e8801
Autor:
Niels JM Verstegen, Ruth R Hagen, Jet van den Dijssel, Lisan H Kuijper, Christine Kreher, Thomas Ashhurst, Laura YL Kummer, Maurice Steenhuis, Mariel Duurland, Rivka de Jongh, Nina de Jong, C Ellen van der Schoot, Amélie V Bos, Erik Mul, Katherine Kedzierska, Koos PJ van Dam, Eileen W Stalman, Laura Boekel, Gertjan Wolbink, Sander W Tas, Joep Killestein, Zoé LE van Kempen, Luuk Wieske, Taco W Kuijpers, Filip Eftimov, Theo Rispens, S Marieke van Ham, Anja ten Brinke, Carolien E van de Sandt, On behalf of the T2B! immunity against SARS-CoV-2 study group
Publikováno v:
eLife, Vol 11 (2022)
Background: Patients affected by different types of autoimmune diseases, including common conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated with immunosuppressants to suppress disease activity. It is not full
Externí odkaz:
https://doaj.org/article/731224c95d814455a088b97c4f3d1a9f
Autor:
Astrid van Tubergen, Gertjan Wolbink, Alejandro Balsa, Victoria Navarro-Compán, Denis Mulleman, John Isaac, Meghna Jani, Borja Hernandez-Breijo, Johanna Elin Gehin, Charlotte Krieckaert, Guillaume le Mélédo
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/471442294c19484b85813db6535e4958
Autor:
Ronald F van Vollenhoven, Sander W Tas, Taco W Kuijpers, Maarten Boers, Michael T Nurmohamed, Gertjan Wolbink, Irene E van der Horst-Bruinsma, Theo Rispens, Willem Lems, Alexandre Voskuyl, Carla A Wijbrandts, S Marieke van Ham, Martijn Gerritsen, Erik H Vogelzang, Luuk Wieske, Laura Boekel, Femke Hooijberg, Yaëlle R Besten, Maureen Leeuw, Sadaf Atiqi, C Krieckaert, Bas Dijkshoorn, Siham Bakhlakh, Juliette J Crooijmans, Filip Eftimov, Laura Y Kummer, PJ Koos van Dam, Eileen W Stalman, Maurice Steenhuis, Sofie Keijzer, Olvi Cristianawati, Jim Keijser, Floris C Loeff
Publikováno v:
RMD Open, Vol 8, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/c31dbe2993a2456ab42dc303970a81d9
Autor:
Laura Boekel, Yaëlle R Besten, Femke Hooijberg, Rosa Wartena, Maurice Steenhuis, Erik Vogelzang, Maureen Leeuw, Sadaf Atiqi, Sander W Tas, Willem F Lems, S Marieke van Ham, Filip Eftimov, Eileen W Stalman, Luuk Wieske, Taco W Kuijpers, Alexandre E Voskuyl, Ronald F van Vollenhoven, Martijn Gerritsen, Charlotte Krieckaert, Theo Rispens, Maarten Boers, Mike T Nurmohamed, Gertjan Wolbink
Publikováno v:
The Lancet Rheumatology, 4(11), e747-e750. Lancet Publishing Group
Boekel, L, Besten, Y R, Hooijberg, F, Wartena, R, Steenhuis, M, Vogelzang, E, Leeuw, M, Atiqi, S, Tas, S W, Lems, W F, van Ham, S M, Eftimov, F, Stalman, E W, Wieske, L, Kuijpers, T W, Voskuyl, A E, van Vollenhoven, R F, Gerritsen, M, Krieckaert, C, Rispens, T, Boers, M, Nurmohamed, M T & Wolbink, G 2022, ' SARS-CoV-2 breakthrough infections in patients with immune-mediated inflammatory diseases during the omicron dominant period ', The Lancet Rheumatology, vol. 4, no. 11, pp. e747-e750 . https://doi.org/10.1016/S2665-9913(22)00221-1
The Lancet. Rheumatology, 4(11), e747-e750
Boekel, L, Besten, Y R, Hooijberg, F, Wartena, R, Steenhuis, M, Vogelzang, E, Leeuw, M, Atiqi, S, Tas, S W, Lems, W F, van Ham, S M, Eftimov, F, Stalman, E W, Wieske, L, Kuijpers, T W, Voskuyl, A E, van Vollenhoven, R F, Gerritsen, M, Krieckaert, C, Rispens, T, Boers, M, Nurmohamed, M T & Wolbink, G 2022, ' SARS-CoV-2 breakthrough infections in patients with immune-mediated inflammatory diseases during the omicron dominant period ', The Lancet Rheumatology, vol. 4, no. 11, pp. e747-e750 . https://doi.org/10.1016/S2665-9913(22)00221-1
The Lancet. Rheumatology, 4(11), e747-e750
Autor:
Kazuyoshi, Ishigaki, Saori, Sakaue, Chikashi, Terao, Yang, Luo, Kyuto, Sonehara, Kensuke, Yamaguchi, Tiffany, Amariuta, Chun Lai, Too, Vincent A, Laufer, Ian C, Scott, Sebastien, Viatte, Meiko, Takahashi, Koichiro, Ohmura, Akira, Murasawa, Motomu, Hashimoto, Hiromu, Ito, Mohammed, Hammoudeh, Samar Al, Emadi, Basel K, Masri, Hussein, Halabi, Humeira, Badsha, Imad W, Uthman, Xin, Wu, Li, Lin, Ting, Li, Darren, Plant, Anne, Barton, Gisela, Orozco, Suzanne M M, Verstappen, John, Bowes, Alexander J, MacGregor, Suguru, Honda, Masaru, Koido, Kohei, Tomizuka, Yoichiro, Kamatani, Hiroaki, Tanaka, Eiichi, Tanaka, Akari, Suzuki, Yuichi, Maeda, Kenichi, Yamamoto, Satoru, Miyawaki, Gang, Xie, Jinyi, Zhang, Christopher I, Amos, Edward, Keystone, Gertjan, Wolbink, Irene, van der Horst-Bruinsma, Jing, Cui, Katherine P, Liao, Robert J, Carroll, Hye-Soon, Lee, So-Young, Bang, Katherine A, Siminovitch, Niek, de Vries, Lars, Alfredsson, Solbritt, Rantapää-Dahlqvist, Elizabeth W, Karlson, Sang-Cheol, Bae, Robert P, Kimberly, Jeffrey C, Edberg, Xavier, Mariette, Tom, Huizinga, Philippe, Dieudé, Matthias, Schneider, Martin, Kerick, Joshua C, Denny, Koichi, Matsuda, Keitaro, Matsuo, Tsuneyo, Mimori, Fumihiko, Matsuda, Keishi, Fujio, Yoshiya, Tanaka, Atsushi, Kumanogoh, Matthew, Traylor, Cathryn M, Lewis, Stephen, Eyre, Huji, Xu, Richa, Saxena, Thurayya, Arayssi, Yuta, Kochi, Katsunori, Ikari, Masayoshi, Harigai, Peter K, Gregersen, Kazuhiko, Yamamoto, S, Louis Bridges, Leonid, Padyukov, Javier, Martin, Lars, Klareskog, Yukinori, Okada, Soumya, Raychaudhuri
Publikováno v:
Nature Genetics, 54, 1640-1651
The Biobank Japan Project 2022, ' Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis ', Nature Genetics, vol. 54, no. 11, pp. 1640-1651 . https://doi.org/10.1038/s41588-022-01213-w
Nature genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54(11), 1640-+. NATURE PORTFOLIO
Nature Genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54, 11, pp. 1640-1651
Nat Genet
The Biobank Japan Project 2022, ' Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis ', Nature Genetics, vol. 54, no. 11, pp. 1640-1651 . https://doi.org/10.1038/s41588-022-01213-w
Nature genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54(11), 1640-+. NATURE PORTFOLIO
Nature Genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54, 11, pp. 1640-1651
Nat Genet
Multi-ancestry genome-wide association analyses identify 124 risk loci for rheumatoid arthritis, of which 34 are novel. A polygenic risk score based on multi-ancestry data showed comparable performance between populations of European and East Asian a