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Autor:
Mirella Ezban, Gertie Westerlund, Bengt Lindblad, Jan Holst, Ulla Hedner, P. Østergaard, Ole Nordfang, Claus Bregengaard
Publikováno v:
Thrombosis Research. 81:461-470
Tissue Factor Pathway Inhibitor (TFPI) is a naturally occurring inhibitor of the TFFVIIa induced coagulation in the presence of FXa. Recombinant two domain TFPI, where Asn 117 on the FXa-inhibitory domain was exchanged to a Gln yielding non-glycosyla