Dilated fixed pupils and respiratory failure: a rare clinical course of Lambert-Eaton myasthenic syndrome

Autor: Gert W van Dijk, AAD VERRIPS, Michelle FM ten Brinck, Inge WH Verheijen, Jaron van de Wardt, Frouke AP Nijhuis

Publikováno v: BMJ Neurology Open, Vol 5, Iss 2 (2023)

Background Lambert-Eaton myasthenic syndrome (LEMS) is a neuromuscular junction disorder and the clinical triad consists of proximal muscle weakness, autonomic symptoms and reduced tendon reflexes. Sluggish pupillary reflexes are common but dilated f

Externí odkaz: https://doaj.org/article/17bac9f518344fb8b36fa0bf715ae593

Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP)

Autor: Sophie A van den Berg, Simone M Uniken Venema, Hendrik Reinink, Jeannette Hofmeijer, Wouter J Schonewille, Irene Miedema, Puck S S Fransen, D Martijn O Pruissen, Theodora W M Raaijmakers, Gert W van Dijk, Frank-Erik de Leeuw, Jorine A van Vliet, Vincent I H Kwa, Henk Kerkhoff, Alex van 't Net, Rene Boomars, Arjen Siegers, Tycho Lok, Klaartje Caminada, Laura M Esteve Cuevas, Marieke C Visser, Casper P Zwetsloot, Jooske M F Boomsma, Mirjam H Schipper, Roeland P J van Eijkelenburg, Olvert A Berkhemer, Daan Nieboer, Hester F Lingsma, Bart J Emmer, Robert J van Oostenbrugge, Aad van der Lugt, Yvo B W E M Roos, Charles B L M Majoie, Diederik W J Dippel, Paul J Nederkoorn, H Bart van der Worp, Ayla van Ahee, Frank Visseren, Patricia Halkes, Ruben van Eijk, Michelle Simons, Wilma Pellikaan, Wilma Van Wijngaarden, Eva Ponjee, Petra Geijtenbeek, Ton Arts, Elles Zock, Wilma Oudshoorn, Frans Steenwinkel, Hamdia Samim, Mark van Zandwijk, Lisette Vrielink, Peter Jan Mulder, Aico Gerritsen, Jim Ijzermans, Marjan Kooijman, Oscar Francissen, Rick van Nuland, Wim van Zwam, Linda Jacobi, Rene van den Berg, Ludo Beenen, Adriaan van Es, Pieter-Jan van Doormaal, Geert Lycklama a Nijeholt, Ido van den Wijngaard, Albert Yoo, Lonneke Yo, Jasper Martens, Bas Hammer, Stefan Roosendaal, Anton Meijer, Menno Krietemeijer, Reinoud Bokkers, Anouk van der Hoorn, Dick Gerrits, Jonathan Coutinho, Ben Jansen, Sanne Manschot, Peter Koudstaal, Koos Keizer, Vicky Chalos, Adriaan Versteeg, Lennard Wolff, Henk van Voorst, Matthijs van der Sluijs, Arnolt-Jan Hoving, Kilian Treurniet, Natalie LeCouffe, Rob van de Graaf, Robert-Jan Goldhoorn, Wouter Hinseveld, Anne Pirson, Lotte Sondag, Manon Kappelhof, Manon Tolhuisen, Josje Brouwer, Wouter van der Steen, Leon Rinkel, Agnetha Bruggeman, Rita Sprengers, Martin Sterrenberg, Sabrina Verheesen, Leontien Heiligers, Yvonne Martens, Naziha El Ghannouti, Miranda Slotboom

Publikováno v: Lancet Neurology, 21(11), 971-981. Elsevier Science
MR ASAP Investigators 2022, ' Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP) : an ambulance-based, multicentre, randomised, open-label, blinded endpoint, phase 3 trial ', The Lancet Neurology, vol. 21, no. 11, pp. 971-981 . https://doi.org/10.1016/S1474-4422(22)00333-7
The Lancet Neurology, 21(11), 971-981. Lancet Publishing Group
Lancet Neurology, 21, 971-981
Lancet Neurology, 21, 11, pp. 971-981
Lancet Neurology, 21(11), 971-981. ELSEVIER SCIENCE INC

Contains fulltext : 287508.pdf (Publisher’s version ) (Closed access) BACKGROUND: Pooled analyses of previous randomised studies have suggested that very early treatment with glyceryl trinitrate (also known as nitroglycerin) improves functional out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee59631545f126c08786122d88c5021
https://hdl.handle.net/11370/4be8e5ea-ce73-44cc-9467-53e548a0319e

Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial

Autor: Christa Walgaard, Bart C Jacobs, Hester F Lingsma, Ewout W Steyerberg, Bianca van den Berg, Alexandra Y Doets, Sonja E Leonhard, Christine Verboon, Ruth Huizinga, Judith Drenthen, Samuel Arends, Ilona Kleine Budde, Ruud P Kleyweg, Krista Kuitwaard, Marjon F G van der Meulen, Johnny P A Samijn, Frederique H Vermeij, Jan B M Kuks, Gert W van Dijk, Paul W Wirtz, Filip Eftimov, Anneke J van der Kooi, Marcel P J Garssen, Cees J Gijsbers, Maarten C de Rijk, Leo H Visser, Roderik J Blom, Wim H J P Linssen, Elly L van der Kooi, Jan J G M Verschuuren, Rinske van Koningsveld, Rita J G Dieks, H Job Gilhuis, Korné Jellema, Taco C van der Ree, Henriette M E Bienfait, Catharina G Faber, Harry Lovenich, Baziel G M van Engelen, Rutger J Groen, Ingemar S J Merkies, Bob W van Oosten, W Ludo van der Pol, Willem D M van der Meulen, Umesh A Badrising, Martijn Stevens, Albert-Jan J Breukelman, Casper P Zwetsloot, Maaike M van der Graaff, Marielle Wohlgemuth, Richard A C Hughes, David R Cornblath, Pieter A van Doorn, Bart C. Jacobs, Hester F. Lingsma, Ewout W. Steyerberg, Bianca Van den Berg, Alexandra Y. Doets, Sonja E. Leonhard, Ruud P. Kleyweg, Marjon F.G. Van der Meulen, Johnny P.A. Samijn, Frederique H. Vermeij, Jan B.M. Kuks, Gert W. Van Dijk, Paul W. Wirtz, Anneke J. Van der Kooi, Marcel P.J. Garssen, Cees J. Gijsbers, Maarten C. De Rijk, Leo H. Visser, Roderik J. Blom, Wim H.J.P. Linssen, Elly L. Van der Kooi, Jan J.G.M. Verschuuren, Rinske Van Koningsveld, Rita J.G. Dieks, H. Job Gilhuis, Taco C. Van der Ree, Henriette M.E. Bienfait, Karin G. Faber, Baziel G.M. Van Engelen, Rutger J. Groen, Ingemar S.J. Merkies, Bob W. Van Oosten, W. Ludo Van der Pol, Willem D.M. Van der Meulen, Umesh A. Badrising, Albert-Jan J. Breukelman, Casper P. Zwetsloot, Maaike M. Van der Graaff, Richard A.C. Hughes, David R. Cornblath, Pieter A. Van Doorn, R.B. Althingh van Geusau, C.J.M. Van Boheemen, I.M. Bronner, B. Feenstra, C. Fokke, T.A. Hoogendoorn, R. Van Houten, A. Hovestad, P.J.H.W. Jansen, E. Keuter, J. Krudde, F.H.H. Linn, J. Lion, S.M. Manschot, S.J. Mellema, D.S.M. Molenaar, D.J. Nieuwkamp, D.G. Oenema, J.C.H. Van Oostrom, N.P. Van Orshoven, R.J.O. Van der Ploeg, S. Polman, A. Ruitenberg, L. Ruts, A.J.G.M. Schyns-Soeterboek, R. Trip

Publikováno v: The Lancet Neurology, 20(4), 275-283. Lancet Publishing Group
Walgaard, C, Jacobs, B C, Lingsma, H F, Steyerberg, E W, van den Berg, B, Doets, A Y, Leonhard, S E, Verboon, C, Huizinga, R, Drenthen, J, Arends, S, Budde, I K, Kleyweg, R P, Kuitwaard, K, van der Meulen, M F G, Samijn, J P A, Vermeij, F H, Kuks, J B M, van Dijk, G W, Wirtz, P W, Eftimov, F, van der Kooi, A J, Garssen, M P J, Gijsbers, C J, de Rijk, M C, Visser, L H, Blom, R J, Linssen, W H J P, van der Kooi, E L, Verschuuren, J J G M, van Koningsveld, R, Dieks, R J G, Gilhuis, H J, Jellema, K, van der Ree, T C, Bienfait, H M E, Faber, C G, Lovenich, H, van Engelen, B G M, Groen, R J, Merkies, I S J, van Oosten, B W, van der Pol, W L, van der Meulen, W D M, Badrising, U A, Stevens, M, Breukelman, A-J J, Zwetsloot, C P, van der Graaff, M M, Wohlgemuth, M, Hughes, R A C, Cornblath, D R, van Doorn, P A, Jacobs, B C, Lingsma, H F, Steyerberg, E W, Doets, A Y, Leonhard, S E, Kleine Budde, I, Kleyweg, R P, van der Meulen, M F G, Samijn, J P A, Vermeij, F H, Kuks, J B M, van Dijk, G W, Wirtz, P W, van der Kooi, A J, Garssen, M P J, Gijsbers, C J, de Rijk, M C, Visser, L H, Blom, R J, Linssen, W H J P, van der Kooi, E L, Verschuuren, J J G M, Dieks, R J G, Gilhuis, H J, van der Ree, T C, Bienfait, H M E, Faber, K G, van Engelen, B G M, Groen, R J, Merkies, I S J, van Oosten, B W, van der Pol, W L, van der Meulen, W D M, Badrising, U A, Breukelman, A-J J, Zwetsloot, C P, van der Graaff, M M, Hughes, R A C, Cornblath, D R, van Doorn, P A, Althingh van Geusau, R B, van Boheemen, C J M, Bronner, I M, Feenstra, B, Fokke, C, Hoogendoorn, T A, van Houten, R, Hovestad, A, Jansen, P J H W, Keuter, E, Krudde, J, Linn, F H H, Lion, J, Manschot, S M, Mellema, S J, Molenaar, D S M, Nieuwkamp, D J, Oenema, D G, van Oostrom, J C H, van Orshoven, N P, van der Ploeg, R J O, Polman, S, Ruitenberg, A, Ruts, L, Schyns-Soeterboek, A J G M, Trip, R & Dutch GBS Study Group 2021, ' Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial ', The Lancet Neurology, vol. 20, no. 4, pp. 275-283 . https://doi.org/10.1016/S1474-4422(20)30494-4
The Lancet Neurology, 20(4), 275-283. ELSEVIER SCIENCE INC
Lancet Neurology, 20(4), 275-283. ELSEVIER SCIENCE INC
Lancet Neurology, 20(4), 275-283. Elsevier Science
Lancet Neurology, 20, 275-283
Lancet neurology, 20(4), 275-283. Lancet Publishing Group
Lancet Neurology, 20, 4, pp. 275-283

Summary Background Treatment with one standard dose (2 g/kg) of intravenous immunoglobulin is insufficient in a proportion of patients with severe Guillain-Barre syndrome. Worldwide, around 25% of patients severely affected with the syndrome are give

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac234079bfe0a75e9f04cbd3f24fe28
https://research.vumc.nl/en/publications/ed0fb2cb-ebfd-4d51-a9f8-133541aa7cfa

Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury*

Autor: Gert W. van Dijk, Luke P. H. Leenen, Olaf L. Cremer, Cor J. Kalkman, Erik van Wensen, Geert J. F. Brekelmans, Karel G.M. Moons

Publikováno v: Critical Care Medicine. 33:2207-2213

Intracranial hypertension after severe head injury is associated with case fatality, but there is no sound evidence that monitoring of intracranial pressure (ICP) and targeted management of cerebral perfusion pressure (CPP) improve outcome, despite w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb16118fdfa5e3b26b92eb52fdc03f86
https://doi.org/10.1097/01.ccm.0000181300.99078.b5

Observational Dutch Young Symptomatic StrokE studY (ODYSSEY): study rationale and protocol of a multicentre prospective cohort study

Autor: Maureen J. van der Vlugt, Roy P. C. Kessels, Karlijn F. de Laat, Renate M. Arntz, Rob A.R. Gons, Frank-Erik de Leeuw, Sarah E. Vermeer, Anouk G.W. van Norden, P. J. A. M. Brouwers, Tom den Heijer, Nathalie E. Synhaeve, Gert W. van Dijk, Ewoud J. van Dijk, Mayte E van Alebeek, Paul L.M. de Kort

Publikováno v: BMC Neurology, 14
BMC Neurology

Background The proportion of strokes occurring in younger adults has been rising over the past decade. Due to the far longer life expectancy in the young, stroke in this group has an even larger socio-economic impact. However, information on etiology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b3b3fb662d72d154f7ce7cfe5216f8
https://doi.org/10.1186/1471-2377-14-55