Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Gert Jan Lammers"'
Autor:
Hanna M. Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M. Yogeshwar, Ryan P. Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung-Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaria, Isabelle Arnulf, Stine Knudsen-Heier, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K. Van den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, Francisco J. Martínez-Orozco, Rosa Peraita-Adrados, Antonio Benetó, Jacques Montplaisir, Alex Desautels, Yu-Shu Huang, FinnGen, Poul Jennum, Sona Nevsimalova, David Kemlink, Alex Iranzo, Sebastiaan Overeem, Aleksandra Wierzbicka, Peter Geisler, Karel Sonka, Makoto Honda, Birgit Högl, Ambra Stefani, Fernando Morgadinho Coelho, Vilma Mantovani, Eva Feketeova, Mia Wadelius, Niclas Eriksson, Hans Smedje, Pär Hallberg, Per Egil Hesla, David Rye, Zerrin Pelin, Luigi Ferini-Strambi, Claudio L. Bassetti, Johannes Mathis, Ramin Khatami, Adi Aran, Sheela Nampoothiri, Tomas Olsson, Ingrid Kockum, Markku Partinen, Markus Perola, Birgitte R. Kornum, Sina Rueger, Juliane Winkelmann, Taku Miyagawa, Hiromi Toyoda, Seik-Soon Khor, Mihoko Shimada, Katsushi Tokunaga, Manuel Rivas, Jonathan K. Pritchard, Neil Risch, Zoltan Kutalik, Ruth O’Hara, Joachim Hallmayer, Chun Jimmie Ye, Emmanuel J. Mignot
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here, we dissect disease mechanisms and interactions with environ
Externí odkaz:
https://doaj.org/article/5ce5735744474cff8886bce42fe536b9
Autor:
Kseniia Zub, Jan D. Warncke, Julia van der Meer, Elena S. Wenz, Livia G. Fregolente, Panagiotis Bargiotas, Gülçin Benbir Şenel, Christian Sturzenegger, Gert Jan Lammers, Ulf Kallweit, Markus H. Schmidt, Ramin Khatami, Zhongxing Zhang, Sigrid von Manitius, Silvia Miano, Jens G. Acker, Matthias Strub, Claudio L. A. Bassetti
Publikováno v:
Clinical and Translational Neuroscience, Vol 8, Iss 1, p 2 (2023)
Introduction and aims: Narcolepsy type 1 (NT1) is a central disorder of hypersomnolence (CDH) characterized by excessive daytime sleepiness and cataplexy. The Swiss Narcolepsy Scale (SNS), which includes the updated and short (sSNS) versions, has rec
Externí odkaz:
https://doaj.org/article/9fd0f788a3214f66b6c4c22b38cfba17
Autor:
Rolf Fronczek, Gert Jan Lammers
Publikováno v:
Clinical and Translational Neuroscience, Vol 7, Iss 3, p 28 (2023)
Nearly 25 years have passed since the ground-breaking discovery that hypocretin deficiency underlies human narcolepsy with cataplexy. Over time, it has become increasingly evident that hypocretin deficiency goes beyond the conventional core symptoms,
Externí odkaz:
https://doaj.org/article/d0f2941e92b84533b2d7d0fdbdf57516
Autor:
Jari K. Gool, Rolf Fronczek, Peter Bosma, Johan N. van der Meer, Ysbrand D. van der Werf, Gert Jan Lammers
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The brain activation patterns related to sleep resistance remain to be discovered in health and disease. The maintenance of wakefulness test (MWT) is an objective neuropsychological assessment often used to assess an individual’s ability to resist
Externí odkaz:
https://doaj.org/article/189e36ef54ac46889fdc4995a50eb8ae
Autor:
Jari K. Gool, Rolf Fronczek, Alexander Leemans, Dennis A. Kies, Gert Jan Lammers, Ysbrand D. Van der Werf
Publikováno v:
NeuroImage: Clinical, Vol 24, Iss , Pp - (2019)
Narcolepsy type 1 is caused by a selective loss of hypothalamic hypocretin-producing neurons, resulting in severely disturbed sleep-wake control and cataplexy. Hypocretin-producing neurons project widely throughout the brain, influencing different ne
Externí odkaz:
https://doaj.org/article/715b451373144fd8b83751abc079aa8f
Publikováno v:
Brain Sciences, Vol 10, Iss 7, p 419 (2020)
Vigilance complaints often occur in people with narcolepsy type 1 and severely impair effective daytime functioning. We tested the feasibility of a three-level sustained attention to response task (SART) paradigm within a magnetic resonance imaging (
Externí odkaz:
https://doaj.org/article/723c5fed1df94a45a085608764eb269e
Autor:
Alexander Hoogerhoud, Andreia W. P. Hazewinkel, Robert H. A. M. Reijntjens, Irene M. van Vliet, Martijn S. van Noorden, Gert Jan Lammers, J. Gert van Dijk, Erik J. Giltay
Publikováno v:
Depression Research and Treatment, Vol 2015 (2015)
Background. Sleep disturbances are a key feature of major depression. Electroconvulsive treatment (ECT) may improve polysomnography-assessed sleep characteristics, but its short-term effects on actigraphy-assessed and subjective sleep characteristics
Externí odkaz:
https://doaj.org/article/01161918abc644e19a995a336ac2badf
Autor:
Juliette Faraco, Ling Lin, Birgitte Rahbek Kornum, Eimear E Kenny, Gosia Trynka, Mali Einen, Tom J Rico, Peter Lichtner, Yves Dauvilliers, Isabelle Arnulf, Michel Lecendreux, Sirous Javidi, Peter Geisler, Geert Mayer, Fabio Pizza, Francesca Poli, Giuseppe Plazzi, Sebastiaan Overeem, Gert Jan Lammers, David Kemlink, Karel Sonka, Sona Nevsimalova, Guy Rouleau, Alex Desautels, Jacques Montplaisir, Birgit Frauscher, Laura Ehrmann, Birgit Högl, Poul Jennum, Patrice Bourgin, Rosa Peraita-Adrados, Alex Iranzo, Claudio Bassetti, Wei-Min Chen, Patrick Concannon, Susan D Thompson, Vincent Damotte, Bertrand Fontaine, Maxime Breban, Christian Gieger, Norman Klopp, Panos Deloukas, Cisca Wijmenga, Joachim Hallmayer, Suna Onengut-Gumuscu, Stephen S Rich, Juliane Winkelmann, Emmanuel Mignot
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003270 (2013)
Recent advances in the identification of susceptibility genes and environmental exposures provide broad support for a post-infectious autoimmune basis for narcolepsy/hypocretin (orexin) deficiency. We genotyped loci associated with other autoimmune a
Externí odkaz:
https://doaj.org/article/3ca91a88c9be488cb1b4d498c130f020
Autor:
Yves Dauvilliers, Michel Lecendreux, Gert Jan Lammers, Patricia Franco, Mikhail Poluektov, Christian Caussé, Isabelle Lecomte, Jeanne Marie Lecomte, Philippe Lehert, Jean Charles Schwartz, Giuseppe Plazzi
Publikováno v:
The Lancet Neurology. 22:303-311
Autor:
Benedicte Marie Finger, Annika Triller, Ashley M. Bourke, Gert Jan Lammers, Christian Veauthier, Merve Yildizli, Ulf Kallweit
Publikováno v:
Sleep Medicine. 103:100-105