Zobrazeno 1 - 10
of 497
pro vyhledávání: '"Gert, Storm"'
Autor:
Sitong Zhang, Qiyue Wang, Daniel En Liang Tan, Vritika Sikka, Cheng Han Ng, Yan Xian, Dan Li, Mark Muthiah, Nicholas W. S. Chew, Gert Storm, Lingjun Tong, Jiong‐Wei Wang
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Food‐derived extracellular vesicles (FEVs) are nanoscale membrane vesicles obtained from dietary materials such as breast milk, plants and probiotics. Distinct from other EVs, FEVs can survive the harsh degrading conditions in the gastroin
Externí odkaz:
https://doaj.org/article/96ea098bfe1845a694aec3bc617e2500
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractDiseases affecting the esophagus are common. However, targeted drug delivery to the esophagus is challenging due to the anatomy and physiology of this organ. Current pharmacological treatment for esophageal diseases predominantly relies on th
Externí odkaz:
https://doaj.org/article/5e949a965abf4b21859876b95b165be2
Autor:
Joanna Grabowska, Valentine Léopold, Katarzyna Olesek, Maarten K. Nijen Twilhaar, Alsya J. Affandi, Mieke C. Brouwer, Ilse Jongerius, Admar Verschoor, Cees van Kooten, Yvette van Kooyk, Gert Storm, Cornelis van ‘t Veer, Joke M. M. den Haan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Historically platelets are mostly known for their crucial contribution to hemostasis, but there is growing understanding of their role in inflammation and immunity. The immunomodulatory role of platelets entails interaction with pathogens, but also w
Externí odkaz:
https://doaj.org/article/3541dcb491b24ae2993ad7cfff31a80a
Autor:
Chee Wai Wong, Ning Cheung, James S. Howden, Joanna Marie Fianza Busoy, Shaun Sim, Joshua Lim, Candice Ho, Amutha Barathi Veluchamy, Gert Storm, Tina T. Wong
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
PurposeTo investigate the efficacy of liposomal prednisolone phosphate to mitigate the severity of proliferative vitreoretinopathy (PVR) in a minipig model of PVR.MethodsA total of 18 eyes of 9 minipigs underwent PVR induction surgically. Eyes were r
Externí odkaz:
https://doaj.org/article/0ed223088ecd46dda7aff34229eebcb3
Autor:
Aram M. de Haas, Dorian A. Stolk, Sjoerd T. T. Schetters, Laura Goossens-Kruijssen, Eelco Keuning, Martino Ambrosini, Louis Boon, Hakan Kalay, Gert Storm, Hans J. van der Vliet, Tanja D. de Gruijl, Yvette van Kooyk
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 581 (2024)
Cancer vaccines have emerged as a potent strategy to improve cancer immunity, with or without the combination of checkpoint blockade. In our investigation, liposomal formulations containing synthetic long peptides and α-Galactosylceramide, along wit
Externí odkaz:
https://doaj.org/article/2be967ab56b14c11a0144b1c553fc930
Autor:
Kenan Aloss, Syeda Mahak Zahra Bokhari, Pedro Henrique Leroy Viana, Nino Giunashvili, Csaba András Schvarcz, Gábor Szénási, Dániel Bócsi, Zoltán Koós, Gert Storm, Zsuzsanna Miklós, Zoltán Benyó, Péter Hamar
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3101 (2024)
Modulated electro-hyperthermia (mEHT) is an adjuvant cancer therapy that enables tumor-selective heating (+2.5 °C). In this study, we investigated whether mEHT accelerates the tumor-specific delivery of doxorubicin (DOX) from lyso-thermosensitive li
Externí odkaz:
https://doaj.org/article/d628f93e5d2f4bd0bac481bc6d86149a
Autor:
Praneeth R. Kuninty, Karin Binnemars-Postma, Ahmed Jarray, Kunal P. Pednekar, Marcel A. Heinrich, Helen J. Pijffers, Hetty ten Hoopen, Gert Storm, Peter van Hoogevest, Wouter K. den Otter, Jai Prakash
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Tumor-associated macrophages are mostly pro-tumorigenic, due to their re-programming by the tumor microenvironment. Here authors show that nanoliposomes, incorporating phospholipids with a flipping-tail chain, are engulfed specifically by intratumora
Externí odkaz:
https://doaj.org/article/c7139cc6942449fc878247554c64ac93
Autor:
Rianne Haumann, John I. Bianco, Piotr M. Waranecki, Pieter J. Gaillard, Gert Storm, Mario Ries, Dannis G. van Vuurden, Gertjan J. L. Kaspers, Esther Hulleman
Publikováno v:
Translational Medicine Communications, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Background Diffuse intrinsic pontine glioma (DIPG) is a notoriously difficult tumor to treat, with an overall survival of DIPG patients being only 11 months. One of the major obstacles for the effective treatment of DIPG is the blood–brain
Externí odkaz:
https://doaj.org/article/5b5dfd09014b44798d922fa5cc89f16c
Autor:
Jacinta O. Pinho, Mariana Matias, Vanda Marques, Carla Eleutério, Célia Fernandes, Lurdes Gano, Joana D. Amaral, Eduarda Mendes, Maria Jesus Perry, João Nuno Moreira, Gert Storm, Ana Paula Francisco, Cecília M.P. Rodrigues, M. Manuela Gaspar
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114021- (2023)
The aggressiveness of melanoma and lack of effective therapies incite the discovery of novel strategies. Recently, a new dual acting hybrid molecule (HM), combining a triazene and a ʟ-tyrosine analogue, was synthesized. HM was designed to specifical
Externí odkaz:
https://doaj.org/article/8bcb887236f344f381f68daa3c7e19f5
Autor:
Charis Rousou, Nicky van Kronenburg, Andreas F. P. Sonnen, Marijke van Dijk, Chrit Moonen, Gert Storm, Enrico Mastrobattista, Roel Deckers
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1220 (2023)
Drug delivery to the retina is one of the major challenges in ophthalmology due to the biological barriers that protect it from harmful substances in the body. Despite the advancement in ocular therapeutics, there are many unmet needs for the treatme
Externí odkaz:
https://doaj.org/article/4c3e25033dd34dc18301425251e35cd8