Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Gert, Folkerts"'
Autor:
Gillina F. G. Bezemer, Mara A. P. Diks, Esmaeil Mortaz, Ingrid van Ark, Jeroen van Bergenhenegouwen, Aletta D. Kraneveld, Gert Folkerts, Johan Garssen
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionPulmonary neutrophilia is a hallmark of numerous airway diseases including Chronic Obstructive Pulmonary Disease (COPD), Neutrophilic asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and COVID-19. The aim of the
Externí odkaz:
https://doaj.org/article/566f2b34069b40238c83856d78a5e41f
Autor:
Mehrdad Azarmi, Negisa Seyed Toutounchi, Astrid Hogenkamp, Suzan Thijssen, Saskia A. Overbeek, Johan Garssen, Gert Folkerts, Belinda van’t Land, Saskia Braber
Publikováno v:
Nutrients, Vol 16, Iss 17, p 2858 (2024)
Early-life nutrition significantly impacts vaccination efficacy in infants, whose immune response to vaccines is weaker compared to adults. This study investigated vaccination efficacy in female C57Bl/6JOlaHsd mice (6 weeks old) fed diets with 0.7% g
Externí odkaz:
https://doaj.org/article/e2a931dc3cba42d88c69209b8e67a1c8
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4058 (2024)
Chronic obstructive pulmonary disease (COPD) patients and smokers have a higher incidence of intestinal disorders. The aim of this study was to gain insight into the transcriptomic changes in the lungs and intestines, and the fecal microbial composit
Externí odkaz:
https://doaj.org/article/7063d4cfdd4248bebad4cd8aeb17c856
Autor:
Fatemeh Kiaee, Hamidreza Jamaati, Heshmat Shahi, Neda Dalil Roofchayee, Mohammad Varahram, Gert Folkerts, Johan Garssen, Ian M. Adcock, Esmaeil Mortaz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The pathogenesis of coronavirus disease 2019 (COVID-19) is not fully elucidated. COVID-19 is due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes severe illness and death in some people by causing immune dysregula
Externí odkaz:
https://doaj.org/article/a1c1c7115ffb4646a08bf87fbea39f89
Autor:
Marit Zuurveld, Pien C.J. Kiliaan, Sophie E.L. van Grinsven, Gert Folkerts, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen
Publikováno v:
Journal of Innate Immunity, Pp 1-18 (2022)
Allergic sensitization starts with epithelial cell activation driving dendritic cells (DCs) to instruct T helper 2 (Th2) cell polarization. Food allergens trigger intestinal epithelial cell (IEC) activation. Human milk oligosaccharides may temper the
Externí odkaz:
https://doaj.org/article/054a270b044144938731fc49d65005d1
Publikováno v:
Journal of Advanced Research, Vol 39, Iss , Pp 305-318 (2022)
Introduction: The lack of effective anti-inflammatory therapies for pneumonia represents a challenge for identifying new alternatives. Non-digestible galacto-oligosaccharides (GOS) are attractive candidates due to their anti-inflammatory and immunomo
Externí odkaz:
https://doaj.org/article/b9b0b1ab4c8144e2915e3a6e6666f5c0
Autor:
Maria Eleni Mavrogeni, Mostafa Asadpoor, Jo H. Judernatz, Ingrid van Ark, Marc M. S. M. Wösten, Karin Strijbis, Roland J. Pieters, Gert Folkerts, Saskia Braber
Publikováno v:
Toxins, Vol 15, Iss 10, p 586 (2023)
Clostridioides difficile infection is expected to become the most common healthcare-associated infection worldwide. C. difficile-induced pathogenicity is significantly attributed to its enterotoxin, TcdA, which primarily targets Rho-GTPases involved
Externí odkaz:
https://doaj.org/article/5b11f8c5a56e4b7d8753ec04e12aaf61
Autor:
Esmaeil Mortaz, Hamidreza Jamaati, Neda K.Dezfuli, Hakime Sheikhzade, Seyed MohammadReza Hashemian, Neda Dalil Roofchayee, Frazaneh Dastan, Payam Tabarsi, Gert Folkerts, Johan Garssen, Sharon Mumby, Ian M. Adcock
Publikováno v:
Iranian Journal of Allergy, Asthma and Immunology, Vol 22, Iss 1 (2023)
COVID-19, caused by SARS-CoV-2, requires new approaches to control the disease. Programmed cell death protein (PD-1) and cytotoxic T-lymphocyte–associated protein 4 (CTLA-4) play important roles in T-cell exhaustion in severe COVID-19. This study e
Externí odkaz:
https://doaj.org/article/2cc72d6c71344e0e8bbb229953e18f05
Autor:
Marit Zuurveld, Cristina Bueno Díaz, Frank Redegeld, Gert Folkerts, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundThe global demand of sustainable food sources leads to introduction of novel foods on the market, which may pose a risk of inducing allergic sensitization. Currently there are no validated in vitro assays mimicking the human mucosal immune
Externí odkaz:
https://doaj.org/article/5d2e5dfd5584429cbde675e88d8feb67
Autor:
Charlotte E. Pelgrim, Ingrid van Ark, Ronja E. van Berkum, Anne M. Schuitemaker-Borneman, Inge Flier, Thea Leusink-Muis, Hamed Janbazacyabar, Mara A. P. Diks, Harry R. Gosker, Marco C. J. M. Kelders, Ramon C. J. Langen, Annemie M. W. J. Schols, Robert J. J. Hageman, Saskia Braber, Johan Garssen, Gert Folkerts, Ardy van Helvoort, Aletta D. Kraneveld
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
One cluster of the extrapulmonary manifestations in chronic obstructive pulmonary disease (COPD) is related to the brain, which includes anxiety, depression and cognitive impairment. Brain-related comorbidities are related to worsening of symptoms an
Externí odkaz:
https://doaj.org/article/028086da297a447bb7ad4deb11e61147