Nature Communications / Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

Autor: Schosserer, Markus, Minois, Nadege, Angerer, Tina B., Amring, Manuela, Dellago, Hanna, Harreither, Eva, Calle-Perez, Alfonso, Pircher, Andreas, Gerstl, Matthias Peter, Pfeifenberger, Sigrid, Brandl, Clemens, Sonntagbauer, Markus, Kriegner, Albert, Linder, Angela, Weinhäusel, Andreas, Mohr, Thomas, Steiger, Matthias, Mattanovich, Diethard, Rinnerthaler, Mark, Karl, Thomas, Sharma, Sunny

Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear. Here, we show that reduced levels of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3941::0de436e08bb7e548b5f176657cf3db4d
https://eplus.uni-salzburg.at/doi/10.1038/ncomms7158

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

Autor: Schosserer, Markus, Minois, Nadege, Angerer, Tina B, Amring, Manuela, Dellago, Hanna, Harreither, Eva, Calle-Perez, Alfonso, Pircher, Andreas, Gerstl, Matthias Peter, Pfeifenberger, Sigrid, Brandl, Clemens, Sonntagbauer, Markus, Kriegner, Albert, Linder, Angela, Weinhäusel, Andreas, Mohr, Thomas, Steiger, Matthias, Mattanovich, Diethard, Rinnerthaler, Mark, Karl, Thomas, Sharma, Sunny, Entian, Karl-Dieter, Kos, Martin, Breitenbach, Michael, Wilson, Iain B H, Polacek, Norbert, Grillari-Voglauer, Regina, Breitenbach-Koller, Lore, Grillari, Johannes

Publikováno v: Nature Communications
Schosserer, Markus; Minois, Nadege; Angerer, Tina B.; Amring, Manuela; Dellago, Hanna; Harreither, Eva; Calle-Perez, Alfonso; Pircher, Andreas; Gerstl, Matthias Peter; Pfeifenberger, Sigrid; Brandl, Clemens; Sonntagbauer, Markus; Kriegner, Albert; Linder, Angela; Weinhäusel, Andreas; Mohr, Thomas; Steiger, Matthias; Mattanovich, Diethard; Rinnerthaler, Mark; Karl, Thomas; ... (2015). Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan. Nature communications, 6(6158), p. 6158. Nature Publishing Group 10.1038/ncomms7158

Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear. Here, we show that reduced levels of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50ce94154f839ee9720757b381e9ca4d
https://pubmed.ncbi.nlm.nih.gov/27167997

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Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

Autor: Brandl, Clemens, Grillari-Voglauer, Regina, Grillari, Johannes, Amring, Manuela, Calle-Perez, Alfonso, Entian, Karl-Dieter, Sharma, Sunny, Dellago, Hanna, Schosserer, Markus, Linder, Angela, Rinnerthaler, Mark, Breitenbach, Michael, Sonntagbauer, Markus, Karl, Thomas, Breitenbach-Koller, Lore, Pircher, Andreas, Mohr, Thomas, Steiger, Matthias, Gerstl, Matthias Peter, Kriegner, Albert, Pfeifenberger, Sigrid, Wilson, Iain B.H., Angerer, Tina B., Polacek, Norbert, Harreither, Eva, Weinhäusel, Andreas, Minois, Nadege, Kos, Martin, Mattanovich, Diethard

Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear. Here, we show that reduced levels of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f65ac44a0339974b895660989aa7f532