Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Gerson M Ferreira"'
1
Akademický článek
NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells.
Autor: Bruno R B Pires, Andre L Mencalha, Gerson M Ferreira, Waldemir F de Souza, José A Morgado-Díaz, Amanda M Maia, Stephany Corrêa, Eliana S F W Abdelhay
Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0169622 (2017)
The metastatic process in breast cancer is related to the expression of the epithelial-to-mesenchymal transition transcription factors (EMT-TFs) SNAIL, SLUG, SIP1 and TWIST1. EMT-TFs and nuclear factor-κB (NF-κB) activation have been associated wit
Externí odkaz: https://doaj.org/article/bcaf431d4c094e95ac15c4f1257cee59
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2
Akademický článek
Forkhead box M1 (FoxM1) gene is a new STAT3 transcriptional factor target and is essential for proliferation, survival and DNA repair of K562 cell line.
Autor: André L Mencalha, Renata Binato, Gerson M Ferreira, Barbara Du Rocher, Eliana Abdelhay
Publikováno v: PLoS ONE, Vol 7, Iss 10, p e48160 (2012)
The forkhead box (Fox) M1 gene belongs to a superfamily of evolutionarily conserved transcriptional regulators that are involved in a wide range of biological processes, and its deregulation has been implicated in cancer survival, proliferation and c
Externí odkaz: https://doaj.org/article/b3c35d02fab445a190f3d51a590c2a09
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3
KMT2A-MLLT1 and the Novel SEC16A-KMT2A in a Cryptic 3-Way Translocation t(9;11;19) Present in an Infant With Acute Lymphoblastic Leukemia
Autor: Roberto R.C. de Matos, Gerson M. Ferreira, Claus Meyer, Rolf Marschalek, Patrizia Larghero, Raul C. Ribeiro, Thomas Liehr, Moneeb Othman, Mariana T. de S.M. Bizarro, Elaine Sobral da Costa, Marcelo G.P. Land, Eliana Abdelhay, Renata Binato, Maria Luiza M. Silva
Publikováno v: Journal of Pediatric Hematology/Oncology. 44:e719-e722
About 25% of the patients with the translocation t(11;19)(q23;p13.3)/KMT2A-MLLT1 present three-way or more complex fusions, associated with a worse prognosis, suggesting that a particular mechanism creates functional KMT2A fusions for this condition.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de1adec00b72b2e1c327cdab168dce9
https://doi.org/10.1097/mph.0000000000002386
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4
Twist1 Influences the Expression of Leading Members of the IL-17 Signaling Pathway in HER2-Positive Breast Cancer Cells
Autor: Bárbara Du Rocher, Eliana Abdelhay, Daniel Bulzico, Stephany Corrêa, Everton Cruz dos Santos, Luize G. Lima, Susanne Crocamo, Bruno R. B. Pires, Gerson M. Ferreira, Renata Binato
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12144, p 12144 (2021)
Breast cancer (BC) is a heterogeneous disease composed of multiple subtypes with different molecular characteristics and clinical outcomes. The metastatic process in BC depends on the transcription factors (TFs) related to epithelial-mesenchymal tran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74ad2efa20ad70c0843517e1b91a034
https://pubmed.ncbi.nlm.nih.gov/34830027
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5
A New Complex Karyotype Involving a KMT2A-r Variant Three-Way Translocation in a Rare Clinical Presentation of a Pediatric Patient with Acute Myeloid Leukemia
Autor: Moneeb A.K. Othman, Maria Luiza Macedo Silva, Gerson M. Ferreira, Isabel M. Carreira, Daniela R. Ney Garcia, Raul C. Ribeiro, Roberto R. Capela de Matos, Rolf Marschalek, Elaine Sobral da Costa, Marcelo Gerardin Poirot Land, Claus Meyer, Thomas Liehr, Joana B. Melo
Publikováno v: Cytogenetic and Genome Research. 157:213-219
Patients with childhood acute myeloid leukemia (AML) with complex karyotypes (CKs) have a dismal outcome. However, for patients with a KMT2A rearrangement (KMT2A-r), the prognosis appears to depend on the fusion partner gene rather than the karyotype
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95f0d80edba07c673838763181bef743
https://doi.org/10.1159/000499640
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7
Molecular approaches identify a cryptic MECOM rearrangement in a child with a rapidly progressive myeloid neoplasm
Autor: Gerson M. Ferreira, Elaine Sobral da Costa, Isabel M. Carreira, Marcelo Gerardin Poirot Land, Moneeb A.K. Othman, Joana B. Melo, Bruno Almeida Lopes, Maria Luiza Macedo Silva, Thomas Liehr, Mariana Tavares de Souza, Roberto R. Capela de Matos, Mariana Emerenciano, Raul C. Ribeiro
Publikováno v: Cancer Genetics. 221:25-30
Myeloid neoplasms are a heterogeneous group of hematologic disorders with divergent patterns of cell differentiation and proliferation, as well as divergent clinical courses. Rare recurrent genetic abnormalities related to this group of cancers are a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbe9e1d54926bb79121655dd9b46f86
https://doi.org/10.1016/j.cancergen.2017.12.002
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8
Is there a role for epithelial-mesenchymal transition in adrenocortical tumors?
Autor: Leonardo Vieira Neto, Daniel Bulzico, Marcela Pessoa de Paula, Rocio Hassan, Paulo Antônio Silvestre de Faria, Davi Coe Torres, Mario Vaisman, Bruno R. B. Pires, Gerson M. Ferreira, Eliana Abdelhay, Camila Bravo Maia
Publikováno v: Endocrine. 58:276-288
Epithelial-mesenchymal transition (EMT) is a biological dynamic process by which epithelial cells lose their epithelial phenotype and acquire mesenchymal invasive and migratory characteristics. This has been postulated as an essential step during can
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610ff3f126f91d36e45b86d95c79e00a
https://doi.org/10.1007/s12020-017-1409-z
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9
A Novel TP53 Mutation Associated with TWIST1 and SIP1 Expression in an Aggressive Adrenocortical Carcinoma
Autor: Daniel Bulzico, Paulo Antônio Silvestre de Faria, Gerson M. Ferreira, Rocio Hassan, Davi Coe Torres, Leonardo Vieira Neto, Bruno R. B. Pires, Mario Vaisman, Eliana Abdelhay
Publikováno v: Endocrine Pathology. 28:326-331
Adrenocortical carcinomas (ACC) are very rare tumors related to TP53 mutations mostly in childhood onset cases. Epithelial-mesenchymal transition (EMT) transcription factors TWIST1 and Smad interacting protein 1 (SIP1) are related to poorer outcomes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fd7cfe3d5702d761e5b7e13b9b518c
https://doi.org/10.1007/s12022-017-9482-7
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10
GAS6 Oncogene and Reverse MLLT3-KMT2A Duplications in an Infant with Acute Myeloid Leukemia and a Novel Complex Hyperdiploid Karyotype: Detailed High-Resolution Molecular Cytogenetic Studies
Autor: Maria Luiza Macedo Silva, Mariana Tavares de Souza, Daniela R. Ney Garcia, Roberto R. Capela de Matos, Gerson M. Ferreira, Moneeb A.K. Othman, Elaine Cifoni, Edna K. Carboni, Raul C. Ribeiro, Thomas Liehr
Publikováno v: Cytogenetic and Genome Research. 152:33-37
Pediatric acute myeloid leukemia (AML) is a highly heterogeneous disease, presenting cytogenetic and molecular abnormalities which turned out to be critical prognostic factors. Ploidy changes as gain or loss of individual chromosomes are rare in AML,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d929e0b55487f266550ac01cdaeab88c
https://doi.org/10.1159/000477108
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