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Publikováno v:
Neurobiology of Stress, Vol 21, Iss , Pp 100502- (2022)
Chronic stress has been proposed as a driver of altered brain structure and function, including the pathogenesis of neurodegenerative diseases and a driver of disease progression. A key outcome of stress in the brain is structural remodeling of neura
Externí odkaz:
https://doaj.org/article/e9599b8a21e54e218fe53b446ee5e4e9
Autor:
Adam C. Raikes, Gerson D. Hernandez, Veronica A. Mullins, Yiwei Wang, Claudia Lopez, William D. S. Killgore, Floyd H. Chilton, Roberta D. Brinton
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ContextRepetitive sub-concussive head impacts (RSHIs) are common in American football and result in changes to the microstructural integrity of white matter. Both docosahexaenoic acid (DHA) and eicosapentaoic acid (EPA) supplementation exerted neurop
Externí odkaz:
https://doaj.org/article/ded2265f8cf041fab02a5039876598d0
Autor:
Clarissa F. D. Carneiro, Victor G. S. Queiroz, Thiago C. Moulin, Carlos A. M. Carvalho, Clarissa B. Haas, Danielle Rayêe, David E. Henshall, Evandro A. De-Souza, Felippe E. Amorim, Flávia Z. Boos, Gerson D. Guercio, Igor R. Costa, Karina L. Hajdu, Lieve van Egmond, Martin Modrák, Pedro B. Tan, Richard J. Abdill, Steven J. Burgess, Sylvia F. S. Guerra, Vanessa T. Bortoluzzi, Olavo B. Amaral
Publikováno v:
Research Integrity and Peer Review, Vol 5, Iss 1, Pp 1-19 (2020)
Abstract Background Preprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completene
Externí odkaz:
https://doaj.org/article/3f111683ecee44ac9e14acf2cc92366c
Autor:
Adam C. Raikes, Gerson D. Hernandez, Dawn C. Matthews, Ana S. Lukic, Meng Law, Yonggang Shi, Lon S. Schneider, Roberta D. Brinton
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Allopregnanolone (ALLO), an endogenous neurosteroid, promoted neurogenesis and oligogenesis and restored cognitive function in animal models of Alzheimer's disease (AD). Based on these discovery research findings, we conducted a
Externí odkaz:
https://doaj.org/article/b053f6f6db734490a34e7282889c5275
Autor:
Thais G. Moreira, Kimble T. F. Matos, Giovana S. De Paula, Thais M. M. Santana, Raquel G. Da Mata, Fernando C. Pansera, Andre S. Cortina, Marcelle G. Spinola, Clare M. Baecher-Allan, Gerson D. Keppeke, Jules Jacob, Vaseem Palejwala, Karen Chen, Saef Izzy, Brian C. Healey, Rafael M. Rezende, Rogerio A. Dedivitis, Kunwar Shailubhai, Howard L. Weiner
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/ad921884fc424e0688f770608f9a93f2
Publikováno v:
In Schizophrenia Research May 2019 207:3-11
Autor:
Thais G. Moreira, Kimble T. F. Matos, Giovana S. De Paula, Thais M. M. Santana, Raquel G. Da Mata, Fernando C. Pansera, Andre S. Cortina, Marcelle G. Spinola, Clare M. Baecher-Allan, Gerson D. Keppeke, Jules Jacob, Vaseem Palejwala, Karen Chen, Saef Izzy, Brian C. Healey, Rafael M. Rezende, Rogerio A. Dedivitis, Kunwar Shailubhai, Howard L. Weiner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundImmune hyperactivity is an important contributing factor to the morbidity and mortality of COVID-19 infection. Nasal administration of anti-CD3 monoclonal antibody downregulates hyperactive immune responses in animal models of autoimmunity
Externí odkaz:
https://doaj.org/article/b1a9e151506d41928c312969f7c3db27
Autor:
Gerson D. Benítez-Azahares
Publikováno v:
Ciencia & Futuro, Vol 10, Iss 4 (2020)
Se valoraron los posibles usos de la Medicina Natural y Tradicional para el tratamiento de diferentes enfermedades, teniendo en cuenta las propiedades de las plantas medicinales desde el punto de vista físico, químico y biológico, así como su loc
Externí odkaz:
https://doaj.org/article/74fa2ddcda5848bca62107a996538e3d
Autor:
Gerson D. Hernandez, Christine M. Solinsky, Wendy J. Mack, Naoko Kono, Kathleen E. Rodgers, Chun‐Yi Wu, Ana R. Mollo, Claudia M. Lopez, Sonia Pawluczyk, Gerhard Bauer, Dawn Matthews, Yonggang Shi, Meng Law, Michael A. Rogawski, Lon S. Schneider, Roberta D. Brinton
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Allopregnanolone is an endogenous neurosteroid with the potential to be a novel regenerative therapeutic for Alzheimer's disease (AD). Foundations of mechanistic understanding and well‐established preclinical safety efficacy m
Externí odkaz:
https://doaj.org/article/5850674a3da74dfebad3206ffcd3f5dc