Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gerry Sullivan"'
512$\,\times\,$512 Individually Addressable MWIR LED Arrays Based on Type-II InAs/GaSb Superlattices
Autor:
John P. Prineas, Amal Ikhlassi, Gerry Sullivan, Rodney McGee, Keith W. Goossen, John Lawler, Jonathon T. Olesberg, Jonathan Dickason, Dennis Norton, L. M. Murray, Nicholas Waite, Thomas F. Boggess, Fouad Kiamilev, Edwin J. Koerperick
Publikováno v:
IEEE Journal of Quantum Electronics. 49:753-759
Single element 33×33 μm2 InAs/GaSb superlattice light-emitting diodes (SLEDs) operating at 77 K with peak emission at approximately 4.6 μm are demonstrated. A peak radiance of 2.2 W/cm2/sr was measured corresponding to an apparent temperature grea
Publikováno v:
Education for Primary Care. 18:724-735
(2007). The Acceptability, Feasibility and Educational Impact of a New Tool for Formative Assessment of the Consultation Performance of Specialty Registrars in an Irish General Practice Training Scheme. Education for Primary Care: Vol. 18, No. 6, pp.
Autor:
Thomas J. Sowin, Wang Xilu, Steve O’Conner, Lisa A. Hasvold, Wen-Zhen Gu, Hing L. Sham, Jerry Cohen, Gary T. Wang, Robert Gentiles, Haiying Zhang, Charles W. Hutchins, Gerry Sullivan, Weibo Wang, Saul H. Rosenberg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:153-158
A non-methionine FT inhibitor lead structure ( 1 ) was designed through computer modeling of the peptidomimetic FT inhibitor ABT839. Optimization of this lead resulted in compounds 2e and 2g , with FT IC 50 values of 1.3 and 1.8 nM, GGT IC 50 of 1400
Autor:
Jerry Cohen, Shi Chung Ng, Dave Janowick, Hing L. Sham, Daniel A. Dickman, Saul H. Rosenberg, Peter Kovar, Steve Tahir, Robert B. Warner, Haichao Zhang, Sajeev Cherian, David J. Augeri, Badr Saeed, Gerry Sullivan, Douglas Kalvin, Jang Lee, Hong Ding, John J. Larsen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:1069-1074
Potent and orally bioavailable nonthiol-containing inhibitors of protein farnesyltransferase are described. Oral bioavailability was achieved by replacement of the pyridyl ether moiety of 1 with a 2-substituted furan ether to give 4. Potency was rega
Autor:
Gerry Sullivan, Shi-Chung Ng, Sajeev Cherian, Jerry Cohen, Stephen J. O'Connor, Bruce G. Szczepankiewicz, Saul H. Rosenberg, John J. Larsen, Badr Saeed, Dave Janowick, Edward Devine, Haichao Zhang, Douglas Kalvin, David J. Augeri
Publikováno v:
Journal of Medicinal Chemistry. 41:4288-4300
Potent and selective non-thiol-containing inhibitors of protein farnesyltransferase are described. FTI-276 (1) was transformed into pyridyl ether analogue 19. The potency of pyridyl ether 19 was improved by modification of the biphenyl core to that o
Autor:
Charles W. Hutchins, Jerry Cohen, Kennan C. Marsh, David C. Park, Wang Xilu, Gerry Sullivan, Gary T. Wang, Le Wang, Nan-Horng Lin, Vincent S. Stoll, Qun Li, Nicholas M Leonard, Wen-Zhen Gu, Joy Bauch, Haiying Zhang, Saul H. Rosenberg, Hing L. Sham, Yunsong Tong, Clarissa G. Jakob
Publikováno v:
Journal of medicinal chemistry. 47(3)
A novel series of 4-[(4-cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles have been synthesized as selective farnesyltransferase inhibitors using structure-based design. X-ray cocrystal structures of compound 20-FTase-HFP and A31
Autor:
Gerry Sullivan, John Perkins
Publikováno v:
Computers & Chemical Engineering. 12:v