Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Gerry P. McCann"'
Autor:
Noor Sharrack, Kristopher D. Knott, Gaurav S. Gulsin, Tushar Kotecha, Louise A. E. Brown, Jian L. Yeo, Aldostefano Porcari, Robert D. Adam, Sharmaine Thirunavukarasu, Amrit Chowdhary, Eylem Levelt, James C. Moon, Gerry P. McCann, Marianna Fontana, Peter Kellman, Theresa Munyombwe, Chris P. Gale, David L. Buckley, John P. Greenwood, Peter P. Swoboda, Sven Plein
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metformin is an antihyperglycemic used to treat type 2 diabetes mellitus (T2DM). Patients with T2DM are at increased risk of cardiovascular disease. We explored the association between metformin use and cardiovascular magnetic resonance (CMR
Externí odkaz:
https://doaj.org/article/f658e09e703244519798bd09cc870527
Autor:
Saadia Aslam, Abhishek Dattani, Aseel Alfuhied, Gaurav S. Gulsin, Jayanth R. Arnold, Christopher D. Steadman, Michael Jerosch-Herold, Hui Xue, Peter Kellman, Gerry P. McCann, Anvesha Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Aortic valve replacement (AVR) leads to reverse cardiac remodeling in patients with aortic stenosis (AS). The aim of this secondary pooled analysis was to assess the degree and determinants of changes in myocardial perfusion post AVR, and it
Externí odkaz:
https://doaj.org/article/d4d91e400e664162ab2068acd0176686
Autor:
Olivia C. Leavy, Richard J. Russell, Ewen M. Harrison, Nazir I. Lone, Steven Kerr, Annemarie B. Docherty, Aziz Sheikh, Matthew Richardson, Omer Elneima, Neil J. Greening, Victoria Claire Harris, Linzy Houchen-Wolloff, Hamish J.C. McAuley, Ruth M. Saunders, Marco Sereno, Aarti Shikotra, Amisha Singapuri, Raminder Aul, Paul Beirne, Charlotte E. Bolton, Jeremy S. Brown, Gourab Choudhury, Nawar Diar Bakerly, Nicholas Easom, Carlos Echevarria, Jonathan Fuld, Nick Hart, John R. Hurst, Mark Jones, Dhruv Parekh, Paul Pfeffer, Najib M. Rahman, Sarah Rowland-Jones, Ajay M. Shah, Dan G. Wootton, Caroline Jolley, A.A. Roger Thompson, Trudie Chalder, Melanie J. Davies, Anthony De Soyza, John R. Geddes, William Greenhalf, Simon Heller, Luke Howard, Joseph Jacob, R. Gisli Jenkins, Janet M. Lord, Will D-C. Man, Gerry P. McCann, Stefan Neubauer, Peter J.M. Openshaw, Joanna Porter, Matthew J. Rowland, Janet T. Scott, Malcolm G. Semple, Sally J. Singh, David Thomas, Mark Toshner, Keir Lewis, Liam G. Heaney, Andrew Briggs, Bang Zheng, Mathew Thorpe, Jennifer K. Quint, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Louise V. Wain, Christopher E. Brightling, Rachael A. Evans
Publikováno v:
ERJ Open Research, Vol 10, Iss 5 (2024)
Background In patients with coronavirus disease 2019 (COVID-19) requiring supplemental oxygen, dexamethasone reduces acute severity and improves survival, but longer-term effects are unknown. We hypothesised that systemic corticosteroid administratio
Externí odkaz:
https://doaj.org/article/1d2fc6dbfe284fe4960b0e7810b277e4
Autor:
Joanna M. Bilak, Gaurav S. Gulsin, Vasiliki Bountziouka, Kelly S. Parke, Emma Redman, Joseph Henson, Lei Zhao, Phillipe Costet, Mary Ellen Cvijic, Juan Maya, Ching-Pin Chang, Melanie J. Davies, Thomas Yates, Gerry P. McCann, Emer M. Brady
Publikováno v:
Hearts, Vol 5, Iss 1, Pp 165-181 (2024)
Background: This study assesses the temporal responses of cardiovascular function, fibro-inflammation, and glucometabolic profiles in asymptomatic adults with type 2 diabetes, following a low-energy meal replacement plan (MRP) or exercise training. M
Externí odkaz:
https://doaj.org/article/d1bb9c4412824338a137d2822d795b4f
Autor:
Abhishek Dattani, Emer M. Brady, Prathap Kanagala, Svetlana Stoma, Kelly S. Parke, Anna-Marie Marsh, Anvesha Singh, Jayanth R. Arnold, Alastair J. Moss, Lei Zhao, Mary Ellen Cvijic, Matthew Fronheiser, Shuyan Du, Philippe Costet, Peter Schafer, Leon Carayannopoulos, Ching-Pin Chang, David Gordon, Francisco Ramirez-Valle, Michael Jerosch-Herold, Christopher P. Nelson, Iain B. Squire, Leong L. Ng, Gaurav S. Gulsin, Gerry P. McCann
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) frequently co-exist. There is a limited understanding on whether this coexistence is associated with distinct alterations in myocardial remodellin
Externí odkaz:
https://doaj.org/article/4215841e5eec4d4b893e3592affdca59
Autor:
Emer M. Brady, Thong H. Cao, Alastair J. Moss, Lavanya Athithan, Sarah L. Ayton, Emma Redman, Stavroula Argyridou, Matthew P. M. Graham-Brown, Colleen B. Maxwell, Donald J. L. Jones, Leong Ng, Thomas Yates, Melanie J Davies, Gerry P. McCann, Gaurav S. Gulsin
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Heart failure with preserved ejection fraction (HFpEF) is a heterogenous multi-system syndrome with limited efficacious treatment options. The prevalence of Type 2 diabetes (T2D) continues to rise and predisposes patients to HFpEF
Externí odkaz:
https://doaj.org/article/f14530763f914e7b9f6525e1d8bcef3b
Autor:
Tuan Aqeel Bohoran, Kelly S. Parke, Matthew P. M. Graham-Brown, Mitul Meisuria, Anvesha Singh, Joanne Wormleighton, David Adlam, Deepa Gopalan, Melanie J. Davies, Bryan Williams, Morris Brown, Gerry P. McCann, Archontis Giannakidis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Aortic distensibility (AD) is important for the prognosis of multiple cardiovascular diseases. We propose a novel resource-efficient deep learning (DL) model, inspired by the bi-directional ConvLSTM U-Net with densely connected convolutions,
Externí odkaz:
https://doaj.org/article/3ecd91a38ade451f93804b8f33119041
Publikováno v:
Applied Sciences, Vol 14, Iss 20, p 9218 (2024)
Introduction: Skeletal muscle (SkM) abnormalities are well-recognised in heart failure (HF). We aimed to systematically review studies of SkM energetics in patients with HF at rest and post-exercise using 31phosphorus magnetic resonance spectroscopy
Externí odkaz:
https://doaj.org/article/fc83971017c44b71a9d9139846cf2f1e
Autor:
Kelly S. Parke, Emer M. Brady, Aseel Alfuhied, Rishabh S. Motiwale, Cameron S. Razieh, Anvesha Singh, Jayanth R. Arnold, Matthew P.M. Graham-Brown, Joanna M. Bilak, Sarah L. Ayton, Abhishek Dattani, Jian L. Yeo, Gerry P. McCann, Gaurav S. Gulsin
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 1, Pp 100001- (2024)
Background: Echocardiographic studies indicate South Asian people have smaller ventricular volumes, lower mass and more concentric remodelling than White European people, but there are no data using cardiac MRI (CMR). We aimed to compare CMR quantifi
Externí odkaz:
https://doaj.org/article/d63f01a5017c4c4982d0b67c14058113
Autor:
Abhishek Dattani, Saadia Aslam, Gaurav S. Gulsin, Aseel Alfuhied, Trisha Singh, Shruti S. Joshi, Lucy E. Kershaw, David E. Newby, Gerry P. McCann, Anvesha Singh
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 2, Pp 101074- (2024)
Background: Dysregulated myocardial calcium handling has been demonstrated in ischemic, non-ischemic and diabetic cardiomyopathy. Manganese-enhanced MRI (MEMRI) provides a unique method to quantify in-vivo myocardial calcium uptake but no studies hav
Externí odkaz:
https://doaj.org/article/11f43cb0aed2418aa9545b01f4e3dc4e