Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Gerrit-Jan Weverling"'
Autor:
Carolin Vegvari, Emilie Cauët, Christoforos Hadjichrysanthou, Emma Lawrence, Gerrit-Jan Weverling, Frank de Wolf, Roy M Anderson
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156622 (2016)
BACKGROUND:About 90% of drugs fail in clinical development. The question is whether trials fail because of insufficient efficacy of the new treatment, or rather because of poor trial design that is unable to detect the true efficacy. The variance of
Externí odkaz:
https://doaj.org/article/99964cede7554f8c8c3f28b93082593a
Autor:
Kamilla D. Lettinga, Annelies Verbon, Gerrit-Jan Weverling, Joop F.P. Schellekens, Jeroen W. Den Boer, Ed P.F. Yzerman, Jacobus Prins, Wim G. Boersma, Ruud J. van Ketel, Jan M. Prins, Peter Speelman
Publikováno v:
Emerging Infectious Diseases, Vol 8, Iss 12, Pp 1448-1454 (2002)
After a large outbreak of Legionnaires’ disease in the Netherlands, we determined risk factors for intensive care unit (ICU) admission and death and the impact of adequate therapy on ICU-free survival among 141 hospitalized patients. Overall mortal
Externí odkaz:
https://doaj.org/article/0d37f569a4434df691bed2ffc4c19057
Autor:
Amber Yaqub, Michelle M.J. Mens, Jaco M. Klap, Gerrit Jan Weverling, Paul Klatser, Just P.J. Brakenhoff, Gennady V. Roshchupkin, Mohammad Kamran Ikram, Mohsen Ghanbari, Mohammad Arfan Ikram
Publikováno v:
Alzheimers & Dementia, 19(4), 1194-1203. Elsevier Inc.
Introduction: MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression. Their role in the pathophysiology of dementia and potential as biomarkers remains undetermined. Methods: We conducted a single- (one-by-one) and multi-marker (jo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed88da4b499a41078281f4d7ee764cb0
https://pure.eur.nl/en/publications/f79e4306-4cde-4f30-8c75-1ded83d9f998
https://pure.eur.nl/en/publications/f79e4306-4cde-4f30-8c75-1ded83d9f998
Autor:
Sanaz Sedaghat, J.M. Klap, Albert Hofman, M. Arfan Ikram, L. Gras, Gerrit Jan Weverling, Jaap Goudsmit, Frank de Wolf, Reem Waziry, Mohsen Ghanbari, Henning Tiemeier
Publikováno v:
European Journal of Epidemiology, 34(8), 793-799. Springer Netherlands
European journal of epidemiology, 34(8), 793-799. Springer Netherlands
European journal of epidemiology, 34(8), 793-799. Springer Netherlands
Chronological age alone is not a sufficient measure of the true physiological state of the body. The aims of the present study were to: (1) quantify biological age based on a physiological biomarker composite model; (2) and evaluate its association w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f81129724ef8ad8781f5728372e0458
https://hdl.handle.net/1765/118961
https://hdl.handle.net/1765/118961
Autor:
Michelle M. J. Mens, Silvana C. E. Maas, Jaco Klap, Gerrit Jan Weverling, Paul Klatser, Just P. J. Brakenhoff, Joyce B. J. van Meurs, André G. Uitterlinden, M. Arfan Ikram, Maryam Kavousi, Mohsen Ghanbari
Publikováno v:
Frontiers in Genetics, 11:110. Frontiers Media S.A.
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics
MicroRNAs (miRNAs) are non-coding RNA molecules that regulate gene expression. Extensive research has explored the role of miRNAs in the risk for type 2 diabetes (T2D) and coronary heart disease (CHD) using single-omics data, but much less by leverag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfdb795d0b2b37d595609c112199176
https://pure.eur.nl/en/publications/50d4a5fd-9352-44d7-a7d7-c0334635af33
https://pure.eur.nl/en/publications/50d4a5fd-9352-44d7-a7d7-c0334635af33
Autor:
Sanaz Sedaghat, Wouter Koudstaal, L. Gras, Reem Waziry, J.M. Klap, Stefan Kostense, Kevin McRae-McKee, M. Kamran Ikram, Silvan Licher, Roy M. Anderson, Gerrit Jan Weverling, Mohsen Ghanbari, M. Arfan Ikram, Paulien R. Wermeling, Albert Hofman, Jaap Goudsmit, Frank de Wolf
Publikováno v:
Brain, 143, 1220-1232. Oxford University Press
CSF biomarkers, including total-tau, neurofilament light chain (NfL) and amyloid-β, are increasingly being used to define and stage Alzheimer’s disease. These biomarkers can be measured more quickly and less invasively in plasma and may provide im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b872bb17cd603a4ed4e2d5b89b7c22
https://pure.eur.nl/en/publications/fac6041e-27bd-413a-9ba0-09100209074a
https://pure.eur.nl/en/publications/fac6041e-27bd-413a-9ba0-09100209074a
Autor:
Robyn Jones, Mintu P. Turakhia, Troy C. Sarich, Gerrit Jan Weverling, Jeff Stoddard, John A. Spertus, Leslie A. Saxon, Nnamdi Ezeanochie, Michael C. Gibson, Paul Burton, Jennifer Turgiss, Bob Zambon, Ann Marie Navar, Martin Koldijk, Janeta Nikolovski, John Whang
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251963 (2021)
PLoS ONE
PLoS ONE
Background The success of vaccination efforts to curb the COVID-19 pandemic will require broad public uptake of immunization and highlights the importance of understanding factors associated with willingness to receive a vaccine. Methods U.S. adults
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3474388ea61f20a37dbf75394327ddb8
https://doi.org/10.1371/journal.pone.0251963
https://doi.org/10.1371/journal.pone.0251963
Autor:
Christophe Tzourio, Vilmundur Gudnason, Mei Mei Wong, Eric Boerwinkle, Carol Brayne, Kendra Davis-Plourde, Joshua C. Bis, Leslie Grasset, Sudha Seshadri, Oscar L. Lopez, Kevin McRae-McKee, M. Arfan Ikram, Myriam Fornage, Lori B. Chibnik, Osorio Meirelles, Gerrit Jan Weverling, Daniel Bos, Christoforos Hadjichrysanthou, Jaap Goudsmit, Blossom C. M. Stephan, Frank J. Wolters, Alexa S. Beiser, Stephanie Evans, Reem Waziry, Claudine Berr, Catherine Helmer, Kristoffer Bäckman, Sirwan K.L. Darweesh, Claudia L. Satizabal, Alison Ower, Albert Hofman, Anna Zettergren, Roy M. Anderson, Stéphanie Debette, Lewis H. Kuller, Silke Kern, Ingmar Skoog, Jean-François Dartigues, Fiona E. Matthews, Bruce M. Psaty, Matthew P. Pase, Frank de Wolf, Thomas H. Mosley, Lenore J. Launer, Kamran Ikram, Carole Dufouil
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f3f7d52a25fdae8bdcbad93ca3c925
https://doi.org/10.1016/j.jalz.2018.06.2354
https://doi.org/10.1016/j.jalz.2018.06.2354
Autor:
Muniza Rehman, Troy C. Sutton, Jaap Goudsmit, Wouter Koudstaal, Kanta Subbarao, Kevin W. Bock, Gerrit Jan Weverling, Ian N. Moore, Elaine W. Lamirande
Publikováno v:
Journal of virology, 91(24):e01603-17. American Society for Microbiology
Influenza viruses of the H1N1, H2N2, and H3N2 subtypes have caused previous pandemics. H2 influenza viruses represent a pandemic threat due to continued circulation in wild birds and limited immunity in the human population. In the event of a pandemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc59ebd147f6cc18eaf710ae4fb955e8
https://europepmc.org/articles/PMC5709608/
https://europepmc.org/articles/PMC5709608/
Autor:
Susan Buchbinder, Keith G. Mansfield, Glenda Gray, Omu Anzala, Gerrit Jan Weverling, David Ng’ang’a, Maria G. Pau, Rebecca Dilan, Surita Roux, Nelson L. Michael, Sandra V. Kik, Peter Abbink, Pauli N. Amornkul, Guy de Bruyn, John Hural, Jill Gilmour, Jaap Goudsmit, Athmanundh Dilraj, Dan H. Barouch, Angela Carville, Lindsey R. Baden, Hannah Kibuuka, Sharon L. King, Faruk Sinangil, Kara L. Brandariz, Lori F. Maxfield, Merlin L. Robb, Sarah L. Clark, Linda-Gail Bekker, Michael S. Seaman, Raphael Dolin
Publikováno v:
Vaccine, 29(32), 5203-5209. Elsevier BV
Recombinant adenovirus serotype 5 (rAd5) vaccine vectors for HIV-1 and other pathogens have been shown to be limited by high titers of Ad5 neutralizing antibodies (NAbs) in the developing world. Alternative serotype rAd vectors have therefore been co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78700115266d7e416b4391f367288449
https://doi.org/10.1016/j.vaccine.2011.05.025
https://doi.org/10.1016/j.vaccine.2011.05.025