Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Gerrit Jan, Schuurhuis"'
Autor:
Diana Hanekamp, Jesse M. Tettero, Gert J. Ossenkoppele, Angèle Kelder, Jacqueline Cloos, Gerrit Jan Schuurhuis
Publikováno v:
Cancers, Vol 13, Iss 11, p 2597 (2021)
Measurable residual disease (MRD) in AML, assessed by multicolor flow cytometry, is an important prognostic factor. Progenitors are key populations in defining MRD, and cases of MRD involving these progenitors are calculated as percentage of WBC and
Externí odkaz:
https://doaj.org/article/f67b4200403747439013fbe920609f41
Autor:
Han J.M.P. Verhagen, Noortje van Gils, Tania Martiañez, Anna van Rhenen, Arjo Rutten, Fedor Denkers, David C. de Leeuw, Marjon A. Smit, Mei-Ling Tsui, Louise L.E. de Vos Klootwijk, Renee X. Menezes, Meyram Çil, Margaretha G.M. Roemer, Eline Vermue, Stan Heukelom, Sonja Zweegman, Jeroen J.W.M. Janssen, Gert J. Ossenkoppele, Gerrit Jan Schuurhuis, Linda Smit
Publikováno v:
Cell Reports, Vol 25, Iss 11, Pp 3021-3035.e5 (2018)
Summary: Leukemic stem cells (LSCs) are thought to be the major cause of the recurrence of acute myeloid leukemia (AML) due to their potential for self-renewal. To identify therapeutic strategies targeting LSCs, while sparing healthy hematopoietic st
Externí odkaz:
https://doaj.org/article/786323a84cf84b2ca5db63b64d5ff6a0
Autor:
Satu Mustjoki, Jeroen Janssen, Kimmo Porkka, Gert Ossenkoppele, Dominik Wolf, Sarah Thunberg, Leif Stenke, Sieghart Sopper, Gerrit Jan Schuurhuis, Andreas Hochhaus, Bjørn-Tore Gjertsen, Francis Giles, Thoas Fioretos, Gisela Barbany, Matthias Baldauf, Johan Richter, Noortje Thielen
MPFC gating strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c40b189e3c60ca0bd08a32995c2278
https://doi.org/10.1158/1078-0432.22462772.v1
https://doi.org/10.1158/1078-0432.22462772.v1
Autor:
Satu Mustjoki, Jeroen Janssen, Kimmo Porkka, Gert Ossenkoppele, Dominik Wolf, Sarah Thunberg, Leif Stenke, Sieghart Sopper, Gerrit Jan Schuurhuis, Andreas Hochhaus, Bjørn-Tore Gjertsen, Francis Giles, Thoas Fioretos, Gisela Barbany, Matthias Baldauf, Johan Richter, Noortje Thielen
Purpose: Leukemic stem cells (LSCs) may harbor important resistance to tyrosine kinase inhibitors in chronic myelogenous leukemia (CML). We identified Philadelphia chromosome (Ph)–positive CD34+CD38− bone marrow cells (here denoted LSCs) and addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310a1279b85e13f58c051e09a8263cff
https://doi.org/10.1158/1078-0432.c.6525197.v1
https://doi.org/10.1158/1078-0432.c.6525197.v1
Autor:
Satu Mustjoki, Jeroen Janssen, Kimmo Porkka, Gert Ossenkoppele, Dominik Wolf, Sarah Thunberg, Leif Stenke, Sieghart Sopper, Gerrit Jan Schuurhuis, Andreas Hochhaus, Bjørn-Tore Gjertsen, Francis Giles, Thoas Fioretos, Gisela Barbany, Matthias Baldauf, Johan Richter, Noortje Thielen
Consort diagram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba94982160a58ebb7a425d6367c2f4f
https://doi.org/10.1158/1078-0432.22462769
https://doi.org/10.1158/1078-0432.22462769
Autor:
Satu Mustjoki, Jeroen Janssen, Kimmo Porkka, Gert Ossenkoppele, Dominik Wolf, Sarah Thunberg, Leif Stenke, Sieghart Sopper, Gerrit Jan Schuurhuis, Andreas Hochhaus, Bjørn-Tore Gjertsen, Francis Giles, Thoas Fioretos, Gisela Barbany, Matthias Baldauf, Johan Richter, Noortje Thielen
LSC analysis at 3 months time point by FISH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5618bfc4edc28c523264ef0f12a66eac
https://doi.org/10.1158/1078-0432.22462763
https://doi.org/10.1158/1078-0432.22462763
Autor:
Linda Smit, Gert J. Ossenkoppele, Gerrit Jan Schuurhuis, Walter Pouwels, Arjo P. Rutten, Marjolein C. Olthof, Fedor Denkers, David C. de Leeuw
XLSX file - 54KB, Genes correlated with microRNA-126 expression in 163 AML patients show overlap with stem cell genes: Genes positively and negatively associated with miR-126 expression in 163 AML patients as published by (34). 854 genes were signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be0071c09a534453e4a690227defec8
https://doi.org/10.1158/0008-5472.22400873
https://doi.org/10.1158/0008-5472.22400873
Autor:
Linda Smit, Gert J. Ossenkoppele, Gerrit Jan Schuurhuis, Walter Pouwels, Arjo P. Rutten, Marjolein C. Olthof, Fedor Denkers, David C. de Leeuw
XLSX file - 15KB, MicroRNAs differentially expressed between LSC and HSC (at least 2 out of 3 patients): Upper: MicroRNA expression ratios between CD34+CD38-ALDHlow/dim(LSC) and CD34+CD38-ALDHhigh (HSC) populations obtained from microarray analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205a160304b367da8233636005be81c1
https://doi.org/10.1158/0008-5472.22400879.v1
https://doi.org/10.1158/0008-5472.22400879.v1
Autor:
Elisa Giovannetti, Thomas Würdinger, Godefridus J. Peters, Ugo Boggi, Gerrit-Jan Schuurhuis, Henk M. Verheul, Dieter Fuchs, Daniela Campani, Olaf Van Tellingen, Tonny Lagerweij, Richard J. Honeywell, Mina Maftouh, Elena Galvani, Niccola Funel, Viola Caretti, Amir Avan
PDF file - 1445K, Genetic characterization of the PDAC-FM-GC mouse models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c789aa1fd5699cc13a505f22b2c89b
https://doi.org/10.1158/0008-5472.22396989.v1
https://doi.org/10.1158/0008-5472.22396989.v1
Autor:
Elisa Giovannetti, Thomas Würdinger, Godefridus J. Peters, Ugo Boggi, Gerrit-Jan Schuurhuis, Henk M. Verheul, Dieter Fuchs, Daniela Campani, Olaf Van Tellingen, Tonny Lagerweij, Richard J. Honeywell, Mina Maftouh, Elena Galvani, Niccola Funel, Viola Caretti, Amir Avan
PDF file - 276K, Comparative IHC staining in human samples and orthotopic tumor grafts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfeee1141cd694d61bc50496fd30f46
https://doi.org/10.1158/0008-5472.22396995.v1
https://doi.org/10.1158/0008-5472.22396995.v1