Výsledky vyhledávání - "Gerrard Peck"

Akademický článek

Next Generation Sequencing in Newborn Screening in the United Kingdom National Health Service

Autor: Julia C. van Campen, Elizabeth S. A. Sollars, Rebecca C. Thomas, Clare M. Bartlett, Antonio Milano, Matthew D. Parker, Jennifer Dawe, Peter R. Winship, Gerrard Peck, Darren Grafham, Richard J. Kirk, James R. Bonham, Anne C. Goodeve, Ann Dalton

Publikováno v: International Journal of Neonatal Screening, Vol 5, Iss 4, p 40 (2019)

Next generation DNA sequencing (NGS) has the potential to improve the diagnostic and prognostic utility of newborn screening programmes. This study assesses the feasibility of automating NGS on dried blood spot (DBS) DNA in a United Kingdom National

Externí odkaz: https://doaj.org/article/faab368d1f5843599429ae83d0b11d6f

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Next Generation Sequencing in Newborn Screening in the United Kingdom National Health Service

Autor: Rebecca C. Thomas, Jennifer Dawe, Gerrard Peck, P. R. Winship, James R. Bonham, Elizabeth S. A. Sollars, Matthew Parker, Clare M. Bartlett, Anne Goodeve, Julia van Campen, Darren Grafham, Antonio Milano, Ann Dalton, Richard J. Kirk

Publikováno v: International Journal of Neonatal Screening
Volume 5
Issue 4
International journal of neonatal screening
International Journal of Neonatal Screening, Vol 5, Iss 4, p 40 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1816e1a6b9b253844d6a8094bbe16fa

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Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2‐mediated overgrowth

Autor: P. M. Coan, O. H. Iwajomo, Colin P. Sibley, Abigail L. Fowden, Wolf Reik, Miguel Constância, Graham J. Burton, E. Angiolini, Gerrard Peck, Ionel Sandovici

Publikováno v: The FASEB Journal. 25:1737-1745

The healthy development of the fetus depends on an optimal balance between fetal genetic drive for growth and the maternal ability to provide nutrients through the placenta. Nothing is known about fetal-placental signaling in response to increased fe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2638eb84a94a863fa6754e7ea128b3b
https://doi.org/10.1096/fj.10-175273

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Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors

Autor: Barrie Wilkinson, William A Vousden, Susan M Roe, Teresa A. Foster, Christine Martin, Steven James Moss, Laurence H. Pearl, Lesley S. Sheehan, Chrisostomos Prodromou, Sabine Gaisser, RM Sheridan, Ming-Qiang Zhang, Nikolaos Gaitatzis, Nigel Coates, Susan M. Boyd, Matthew Alan Gregory, Markus Radzom, Mohammad Nur-e-Alam, Gerrard Peck

Publikováno v: Journal of medicinal chemistry. 51(18)

A biosynthetic medicinal chemistry approach was applied to the optimization of the natural product Hsp90 inhibitor macbecin. By genetic engineering, mutants have been created to produce novel macbecin analogues including a nonquinone compound (5) tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1897045480ebfe7998b365de062ab5f
https://pubmed.ncbi.nlm.nih.gov/18800759

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