An Excess of Gene Expression Divergence on the X Chromosome in Drosophila Embryos: Implications for the Faster-X Hypothesis

Autor: Kayserili, Melek A., Gerrard, Dave T., Tomancak, Pavel, Kalinka, Alex T.

Publikováno v: PLoS Genetics. 2012, Volume 8, Issue 12:e1003200, ISSN 1553-7404

The X chromosome is present as a single copy in the heterogametic sex, and this hemizygosity is expected to drive unusual patterns of evolution on the X relative to the autosomes. For example, the hemizgosity of the X may lead to a lower chromosomal

Externí odkaz: http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-180730
http://www.qucosa.de/fileadmin/data/qucosa/documents/18073/journal.pgen.1003200.pdf

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes

Autor: Baxter, Melissa, Withey, Sarah, Harrison, Sean, Segeritz, Charis-Patricia, Zhang, Fang, Atkinson-Dell, Rebecca, Rowe, Cliff, Gerrard, Dave T., Sison-Young, Rowena, Jenkins, Roz, Henry, Joanne, Berry, Andrew A., Mohamet, Lisa, Best, Marie, Fenwick, Stephen W., Malik, Hassan, Kitteringham, Neil R., Goldring, Chris E., Piper Hanley, Karen, Vallier, Ludovic, Hanley, Neil A.

Publikováno v: In Journal of Hepatology March 2015 62(3):581-589

QUANTIFYING THE LIFE-HISTORY RESPONSE TO INCREASED MALE EXPOSURE IN FEMALE DROSOPHILA MELANOGASTER

Autor: Edward, Dominic A., Fricke, Claudia, Gerrard, Dave T., Chapman, Tracey

Publikováno v: Evolution, 2011 Feb 01. 65(2), 564-573.

Externí odkaz: https://www.jstor.org/stable/27920074

Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders

Autor: Gerrard, Dave T., Berry, Andrew A., Jennings, Rachel E., Birket, Matthew J., Zarrineh, Peyman, Garstang, Myles G., Withey, Sarah L., Short, Patrick, Jiménez-Gancedo, Sandra, Firbas, Panos, Donaldson, Ian J., Sharrocks, Andrew D., Piper Hanley, Karen, Hurles, Matthew E., Gómez-Skarmeta, José Luis, Bobola, Nicoletta, Hanley, Neil A.

Publikováno v: Nature Communications
Gerrard, D T, Berry, A, Jennings, R, Birket, M, Zarrineh, P, Garstang, M, Withey, S, Short, P, Jiménez-Ganced, S, Firbas, P N, Donaldson, I, Sharrocks, A, Piper Hanley, K, Hurles, M E, Gomez-Skarmeta, J L, Bobola, N & Hanley, N 2020, ' Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders ', Nature Communications, vol. 11, no. 1, 3920, pp. 3920 . https://doi.org/10.1038/s41467-020-17305-2
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
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© The Author(s) 2020.
How the genome activates or silences transcriptional programmes governs organ formation. Little is known in human embryos undermining our ability to benchmark the fidelity of stem cell differentiation or cell programming,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f30b91a04248ce2af21ba27666f9fbb
http://hdl.handle.net/10261/226280

Faster-X Evolution of Gene Expression in Drosophila

Autor: Kayserili, Melek A., Gerrard, Dave T., Tomancak, Pavel, Kalinka, Alex T.

Publikováno v: PLoS Genetics, Vol 8, Iss 12, p e1003200 (2012)
PLoS Genetics

The X chromosome is present as a single copy in the heterogametic sex, and this hemizygosity is expected to drive unusual patterns of evolution on the X relative to the autosomes. For example, the hemizgosity of the X may lead to a lower chromosomal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a06b0082dc164b1194f11dcbf0c655f
http://europepmc.org/articles/PMC3531489?pdf=render