Zobrazeno 1 - 10
of 1 358
pro vyhledávání: '"Gerotarget"'
Autor:
Fabio Lucidi, Laura Girelli, Antonio Giordano, Gerardo Botti, Andrea Chirico, Federica Galli, Michelino De Laurentiis, Luca Mallia
Publikováno v:
Oncotarget
// Federica Galli 1 , Andrea Chirico 1, 5 , Luca Mallia 2 , Laura Girelli 3 , Michelino De Laurentiis 4 , Fabio Lucidi 1 , Antonio Giordano 5, 6 and Gerardo Botti 7 1 Department of Psychology of Development and Socialization Processes, Sapienza, Univ
Publikováno v:
Oncotarget
The intestine is a high cellular turnover tissue largely dependent on the regenerative function of stem cell throughout life, and a signaling center for the health and viability of organisms. Therefore, better understanding of the mechanisms underlyi
Autor:
Maria J. Guerra, Antonio Dominguez-Meijide, Jose L. Labandeira-Garcia, Rosario Moratalla, Pablo Garrido-Gil
Publikováno v:
Oncotarget
Gastrointestinal dysfunction is a common problem in the elderly. Aging-related changes in interactions between local dopaminergic and renin-angiotensin systems (RAS) have been observed in the brain, renal and vascular tissues. However, it is not know
Autor:
Amany Tawfik, Nehal M. Elsherbiny, Khaled Elmasry, Yutao Liu, Riyaz Mohamed, Isha Sharma, Mohamed Al-Shabrawey
Publikováno v:
Oncotarget
To study Hyperhomocysteinemia (HHcy)-induced epigenetic modifications as potential mechanisms of blood retinal barrier (BRB) dysfunction, retinas isolated from three- week-old mice with elevated level of Homocysteine (Hcy) due to lack of the enzyme c
Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes
Autor:
Xiaomei Wang, Anna Malawista, Feng Qian, Heather G. Allore, Christine M. Ramsey, Ruth R. Montgomery
Publikováno v:
Oncotarget
The multifactorial immune deterioration in aging--termed "inflamm-aging"--is comprised of a state of low-grade, chronic inflammation and complex dysregulation of responses to immune stimulation. The TAM family (Tyro 3, Axl, and Mer) of receptor tyros
Autor:
Radj Gervais, F. Vinas, Jean-Bernard Auliac, Christos Chouaid, Renaud Descourt, Louis Tassy, Hélène Doubre, G. Fraboulet, Laurent Greillier, R. Lamy, Romain Corre, Florian Guisier
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2018, 9 (9), pp.8253-8262. ⟨10.18632/oncotarget.23836⟩
Oncotarget, 2018, 9 (9), pp.8253-8262. ⟨10.18632/oncotarget.23836⟩
Oncotarget, Impact journals, 2018, 9 (9), pp.8253-8262. ⟨10.18632/oncotarget.23836⟩
Oncotarget, 2018, 9 (9), pp.8253-8262. ⟨10.18632/oncotarget.23836⟩
// Romain Corre 1,12 , Radj Gervais 2 , Florian Guisier 3 , Louis Tassy 4 , Florent Vinas 5 , Regine Lamy 6 , Gislaine Fraboulet 7 , Laurent Greillier 8 , Helene Doubre 9 , Renaud Descourt 10 , Christos Chouaid 5 and Jean-Bernard Auliac 11 1 Departme
Publikováno v:
Oncotarget
Transient receptor potential cation channel, subfamily V, member 2 (TRPV2) is a principal candidate for abnormal Ca2+-entry pathways, which is a potential target for therapy of muscular dystrophy and cardiomyopathy. Here, an in silico drug screening
Autor:
Mikiko Ohno, Hao Wang, Takeshi Kimura, Koichi Kashiwado, Risa Kimura, Emiko Arita, Ryoichi Ishibashi, Natsuko Shinmen, Eiichiro Nishi, Kazuki Kobayashi, Kazuo Sugimoto, Toshio Machida, Akiko Taira, Hideyuki Kuroda, Go Tomiyoshi, Katsuro Iwase, Masahiro Mori, Xiao-Meng Zhang, Satoshi Kuwabara, Akiyuki Uzawa, Hideaki Shimada, Ken-ichiro Goto, Mayumi Muto, Masaki Takiguchi, Eiichi Kobayashi, Akiyo Aotsuka, Masaaki Ito, Yoichi Yoshida, Tomoo Matsutani, Takeshi Wada, Koutaro Yokote, Koh Ono, Hirotaka Takizawa, Harukiyo Kawamura, Seiichiro Mine, Ikuo Kamitsukasa, Takaki Hiwasa, Minoru Takemoto, Hiromi Ashino, Yasuo Iwadate, Po-Min Chen, Rika Nakamura
Publikováno v:
Oncotarget
Transient ischemic attack (TIA) is a predictor for cerebral infarction (CI), and early diagnosis of TIA is extremely important for the prevention of CI. We set out to identify novel antibody biomarkers for TIA and CI, and detected matrix metalloprote
Publikováno v:
Oncotarget
We recently discovered a plasma proteolysis pathway, termed the FXII-FVII pathway which is composed of coagulation proteases, and found it to be mainly responsible for the clearance of Aβ42 in the plasma in mice. Aβ42 and Aβ40 are the main Aβ for
Autor:
Hyeong Oh Jeong, Bonggi Lee, Seong Min Kim, Byung Pal Yu, Hae Young Chung, Ki Wung Chung, Kyung Mok Kim, June Whoun Park, Dae Hyun Kim
Publikováno v:
Oncotarget
Age-associated renal fibrosis is related with renal function decline during aging. Imbalance between accumulation and degradation of extracellular matrix is key feature of fibrosis. In this study, RNA-sequencing (RNA-Seq) results based on next-genera