From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow

Autor: Anthony J. F. Reardon, Reza Farmahin, Andrew Williams, Matthew J. Meier, Gregory C. Addicks, Carole L. Yauk, Geronimo Matteo, Ella Atlas, Joshua Harrill, Logan J. Everett, Imran Shah, Richard Judson, Sreenivasa Ramaiahgari, Stephen S. Ferguson, Tara S. Barton-Maclaren

Publikováno v: Frontiers in Toxicology, Vol 5 (2023)

The growing number of chemicals in the current consumer and industrial markets presents a major challenge for regulatory programs faced with the need to assess the potential risks they pose to human and ecological health. The increasing demand for ha

Externí odkaz: https://doaj.org/article/96854b10d2a34e91b4c5508eac32b91d

Female mice exposed to low doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

Autor: Myriam P. Hoyeck, Rayanna C. Merhi, Hannah L. Blair, C. Duncan Spencer, Mikayla A. Payant, Diana I. Martin Alfonso, Melody Zhang, Geronimo Matteo, Melissa J. Chee, Jennifer E. Bruin

Publikováno v: Molecular Metabolism, Vol 42, Iss , Pp 101104- (2020)

Objective: Exposure to persistent organic pollutants is consistently associated with increased diabetes risk in humans. We investigated the short- and long-term impact of transient low-dose dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD) exposure

Externí odkaz: https://doaj.org/article/b17f4917842c4456b9dfa5a56db507a9

Correction to: 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice

Autor: Luis A. Rojas-Colón, Pramod K. Dash, Fabiola A. Morales-Vías, Madeline Lebrón-Dávila, Pedro A. Ferchmin, John B. Redell, Geronimo Maldonado-Martínez, Wanda I. Vélez-Torres

Publikováno v: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-1 (2021)

Externí odkaz: https://doaj.org/article/26cad6d31e6a44f8a3b8707748933cb1

Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice

Autor: Miguel P. Méndez-González, David E. Rivera-Aponte, Jan Benedikt, Geronimo Maldonado-Martínez, Flavia Tejeda-Bayron, Serguei N. Skatchkov, Misty J. Eaton

Publikováno v: Brain Sciences, Vol 10, Iss 2, p 72 (2020)

Epilepsy, characterized by recurrent seizures, affects 1% of the general population. Interestingly, 25% of diabetics develop seizures with a yet unknown mechanism. Hyperglycemia downregulates inwardly rectifying potassium channel 4.1 (Kir4.1) in cult

Externí odkaz: https://doaj.org/article/35907673b6aa46e99c1ee02dcfdad9ba

Physical and Mental Health of Informal Carers from Culturally and Linguistically Diverse (CALD) and Non-CALD Groups in Australia.

Autor: Hussain R; School of Medicine and Psychology, Australian National University, Canberra 0200, Australia., Ahmad D; School of Medicine and Psychology, Australian National University, Canberra 0200, Australia., Malhotra R; Duke-NUS Medical School, Singapore 169857, Singapore., Geronimo MA; Federation of Ethnic Communities' Councils of Australia (FECCA), Canberra 2601, Australia.

Publikováno v: Healthcare (Basel, Switzerland) [Healthcare (Basel)] 2024 Oct 17; Vol. 12 (20). Date of Electronic Publication: 2024 Oct 17.