Výsledky vyhledávání - "Geromichalou, E."

Zinc(II) complexes of 3,5–dibromo–salicylaldehyde and α–diimines: Synthesis, characterization and in vitro and in silico biological profile

Autor: Zianna, A. Geromichalou, E. Geromichalos, G. Fiotaki, A.-M. Hatzidimitriou, A.G. Kalogiannis, S. Psomas, G.

The synthesis of five neutral zinc(II) complexes of 3,5–dibromo–salicyladehyde (3,5–diBr–saloH) in the presence of nitrogen–donor co-ligands 2,2′–bipyridine (bipy), 1,10–phenanthroline (phen), 2,9–dimethyl–1,10–phenanthroline (n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::58b18457c4c3c33e6be8b59a12c44875
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3025489

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Copper(II) complexes with non–steroidal anti–inflammatory drugs: Structural characterization, in vitro and in silico biological profile

Autor: Malis, G. Geromichalou, E. Geromichalos, G.D. Hatzidimitriou, A.G. Psomas, G.

Six novel copper(II) complexes with the non–steroidal anti–inflammatory drugs ibuprofen, loxoprofen, fenoprofen and clonixin as ligands were synthesized and characterized by diverse techniques including single–crystal X–ray crystallography. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::ffe2f34b2df6752a445fe7f501cfe0a5
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3025537

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In vitro and in silico evaluation of the inhibitory effect of a curcumin-based oxovanadium (IV) complex on alkaline phosphatase activity and bacterial biofilm formation

Autor: Katsipis, G. Tsalouxidou, V. Halevas, E. Geromichalou, E. Geromichalos, G. Pantazaki, A.A.

The scientific interest in the development of novel metal-based compounds as inhibitors of bacterial biofilm-related infections and alkaline phosphatase (ALP) deregulating effects is continuous and rising. In the current study, a novel crystallograph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::877bcc1398842fdd58bd2318ec5d15a4
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3003286

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Synthesis, structural determination, in vitro and in silico biological evaluation of divalent or trivalent cobalt complexes with indomethacin

Autor: Perontsis, S. Geromichalou, E. Perdih, F. Hatzidimitriou, A.G. Geromichalos, G.D. Turel, I. Psomas, G.

The interaction of cobalt chloride with the non-steroidal anti-inflammatory drug indomethacin (Hindo) led to the formation of the polymeric complex [Co(indo-O)2(H2O)2(μ-Cl)]n·n(MeOH·H2O) bearing one chlorido bridge between the cobalt atoms. The pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::fe8f116124de44cf054920c37c597f12
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3025713

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Azasteroid alkylators as dual inhibitors of akt and erk signaling for the treatment of ovarian carcinoma

Autor: Dalezis, P. Geromichalou, E. Polonifi, A. Sagredou, S. Nikoleousakos, N. Nikolaou, M. Sarli, V. Panayiotidis, M.I. Trafalis, D.T.

(1) Background: Previous findings show that lactam steroidal alkylating esters display improved therapeutic efficacy with reduced toxicity. The aim of this study was to evaluate the anticancer activity of two newly synthesized aza-steroid alkylators

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::c17a252203f2af5bf844008e3035b1b3
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3078506

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Discovery of steroidal lactam conjugates of POPAM-NH2 with potent anticancer activity

Autor: Trafalis, D. Dalezis, P. Geromichalou, E. Sagredou, S. Sflakidou, E. Voura, M. Grammatikopoulou, M. Gabriel, C. Sarli, V.

Aim: Steroidal prodrugs of nitrogen mustards such as estramustine and prednimustine have proven effective anticancer agents in clinical use since the 1970s. In this work, we aimed to develop steroidal prodrugs of the novel nitrogen mustard POPAM-NH2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::dbbe22a1182ecbca0ef65cfae42e327b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3021400

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