Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Gernot Wolf"'
Autor:
Diana Santacruz, Francis O Enane, Katrin Fundel-Clemens, Martin Giner, Gernot Wolf, Svenja Onstein, Christoph Klimek, Zachary Smith, Bhagya Wijayawardena, Coralie Viollet
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100169- (2024)
Externí odkaz:
https://doaj.org/article/0035d705cae7419e99370a7dd6b92582
Autor:
Lucia Azzollini, Dolores Del Prete, Gernot Wolf, Christoph Klimek, Mattia Saggioro, Fernanda Ricci, Eirini Christodoulaki, Tabea Wiedmer, Alvaro Ingles-Prieto, Giulio Superti-Furga, Lia Scarabottolo
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100166- (2024)
Zinc is an essential trace element that is involved in many biological processes and in cellular homeostasis. In pancreatic β-cells, zinc is crucial for the synthesis, processing, and secretion of insulin, which plays a key role in glucose homeostas
Externí odkaz:
https://doaj.org/article/b2fa08c76d0344f2a94893954e294f90
Autor:
Diana Santacruz, Francis O Enane, Katrin Fundel-Clemens, Martin Giner, Gernot Wolf, Svenja Onstein, Christoph Klimek, Zachary Smith, Bhagya Wijayawardena, Coralie Viollet
Publikováno v:
SLAS Discovery, Vol 27, Iss 2, Pp 140-147 (2022)
Over the last decade, whole transcriptome profiling, also known as RNA-sequencing (RNA-seq), has quickly gained traction as a reliable method for unbiased assessment of gene expression. Integration of RNA-seq expression data into other omics datasets
Externí odkaz:
https://doaj.org/article/bb0e8a9732a44f15a5e8c6e0d9ca077e
Autor:
Hubert J. Sijben, Laura Dall’ Acqua, Rongfang Liu, Abigail Jarret, Eirini Christodoulaki, Svenja Onstein, Gernot Wolf, Simone J. Verburgt, Sylvia E. Le Dévédec, Tabea Wiedmer, Giulio Superti-Furga, Adriaan P. IJzerman, Laura H. Heitman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Excitatory amino acid transporters (EAAT/SLC1) mediate Na+-dependent uptake of extracellular glutamate and are potential drug targets for neurological disorders. Conventional methods to assess glutamate transport in vitro are based on radiolabels, fl
Externí odkaz:
https://doaj.org/article/3013a65420c249ca84a2b5a7b907dc82
KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
Autor:
Gernot Wolf, Alberto de Iaco, Ming-An Sun, Melania Bruno, Matthew Tinkham, Don Hoang, Apratim Mitra, Sherry Ralls, Didier Trono, Todd S Macfarlan
Publikováno v:
eLife, Vol 9 (2020)
The Krüppel-associated box zinc finger protein (KRAB-ZFP) family diversified in mammals. The majority of human KRAB-ZFPs bind transposable elements (TEs), however, since most TEs are inactive in humans it is unclear whether KRAB-ZFPs emerged to supp
Externí odkaz:
https://doaj.org/article/be6a42f12a9c4b1cab7c97cc51dcab90
Autor:
Caitlin E Dunn-Fletcher, Lisa M Muglia, Mihaela Pavlicev, Gernot Wolf, Ming-An Sun, Yueh-Chiang Hu, Elizabeth Huffman, Shivani Tumukuntala, Katri Thiele, Amrita Mukherjee, Sandra Zoubovsky, Xuzhe Zhang, Kayleigh A Swaggart, Katherine Y Bezold Lamm, Helen Jones, Todd S Macfarlan, Louis J Muglia
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2006337 (2018)
Pregnancy and parturition are intricately regulated to ensure successful reproductive outcomes. However, the factors that control gestational length in humans and other anthropoid primates remain poorly defined. Here, we show the endogenous retrovira
Externí odkaz:
https://doaj.org/article/5187b61a9cc04b9bb9eb293210d8a053
Autor:
Jadiel A Wasson, Ashley K Simon, Dexter A Myrick, Gernot Wolf, Shawn Driscoll, Samuel L Pfaff, Todd S Macfarlan, David J Katz
Publikováno v:
eLife, Vol 5 (2016)
Somatic cell nuclear transfer has established that the oocyte contains maternal factors with epigenetic reprogramming capacity. Yet the identity and function of these maternal factors during the gamete to embryo transition remains poorly understood.
Externí odkaz:
https://doaj.org/article/33aa2ce862cf4e4287a8fa5035cbcf2d
Autor:
Jinpu Jin, Sherry Ralls, Elaine Wu, Gernot Wolf, Ming-An Sun, Danielle A. Springer, Rachel L. Cosby, Anna D. Senft, Todd S. Macfarlan
Mammalian brains are larger and more densely packed with neurons than reptiles, but the genetic mechanisms underlying the increased connection complexity amongst neurons are unclear. The expression diversity of clustered protocadherins (Pcdhs), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7869e26e74e2493c4da3a720b5a5bc94
https://doi.org/10.1101/2023.05.08.539838
https://doi.org/10.1101/2023.05.08.539838
Protocol for RNA extraction from cell lines and purification for RNA-Seq.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393dc056c15c09cb882bc5abbdea6c20
Protocol for Western Blotting of the RESOLUTE WT-OE cell lines to check for protein expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536e62318c5d82bf059249f3367d13e4