Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca.

Autor: Matthias Engleder, Melissa Horvat, Anita Emmerstorfer-Augustin, Tamara Wriessnegger, Stefanie Gabriel, Gernot Strohmeier, Hansjörg Weber, Monika Müller, Iwona Kaluzna, Daniel Mink, Martin Schürmann, Harald Pichler

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192653 (2018)

Kievitone hydratase catalyzes the addition of water to the double bond of the prenyl moiety of plant isoflavonoid kievitone and, thereby, forms the tertiary alcohol hydroxy-kievitone. In nature, this conversion is associated with a defense mechanism

Externí odkaz: https://doaj.org/article/4a660db8f24446e894d977551ed86ca9

Evolving the Promiscuity of Elizabethkingia meningoseptica Oleate Hydratase for the Regio‐ and Stereoselective Hydration of Oleic Acid Derivatives

Autor: Daniel Mink, Monika Müller, Martin Schürmann, Erich Leitner, Matthias Engleder, Gernot Strohmeier, Hansjörg Weber, Karl Gruber, Harald Pichler, Georg Steinkellner

Publikováno v: Angewandte Chemie (International Ed. in English)

The addition of water to non‐activated carbon–carbon double bonds catalyzed by fatty acid hydratases (FAHYs) allows for highly regio‐ and stereoselective oxyfunctionalization of renewable oil feedstock. So far, the applicability of FAHYs has be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0be3ceda6c7b9fed745729711d48b2c
https://doi.org/10.1002/anie.201901462

One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases

Autor: Michael Fuchs, Bert van Loo, Kurt Faber, Peter Macheroux, Markus Schober, Florian Hollfelder, Gernot Strohmeier, Michael Toesch, Tanja Knaus

Publikováno v: Angewandte Chemie
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)

Given the fact that the theoretically possible number of racemates is larger than that of symmetric prochiral or meso compounds,1 the development of deracemization methods, which yield a single stereoisomer from a racemate is an important topic.1–3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff7c0e3e9df11e065ad4ec9246d46fb

Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol

Autor: Tamim A. Darwish, Gernot Strohmeier, Tania Kjellerup Lind, Martin Malmsten, V. Trevor Forsyth, Harald Pichler, Marité Cárdenas, Kathryn L. Browning, Sarah Waldie, Michael Haertlein, Martine Moulin, Armando Maestro, Federica Sebastiani, Maximilian W. A. Skoda, Selma Maric, Nageshwar R. Yepuri, Eva Bengtsson

Publikováno v: 'Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids ', vol: 1865, pages: 158769-1-158769-8 (2020)
Waldie, S, Sebastiani, F, Browning, K, Maric, S, Lind, T K, Yepuri, N, Darwish, T A, Moulin, M, Strohmeier, G, Pichler, H, Skoda, M W A, Maestro, A, Haertlein, M, Forsyth, V T, Bengtsson, E, Malmsten, M & Cardenas, M 2020, ' Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol ', B B A-Molecular and Cell Biology of Lipids, vol. 1865, no. 10, 158769 . https://doi.org/10.1016/j.bbalip.2020.158769

Lipoproteins play a central role in the development of atherosclerosis. High and low-density lipoproteins (HDL and LDL), known as ‘good’ and ‘bad’ cholesterol, respectively, remove and/or deposit lipids into the artery wall. Hence, insight in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819dbfc207b7d328875256c4f1080d84
https://doi.org/10.1016/j.bbalip.2020.158769

Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine

Autor: Harald Pichler, Sarah Waldie, Michael Haertlein, Martine Moulin, Tania Kjellerup Lind, Selma Maric, V. Trevor Forsyth, Kathryn L. Browning, Marité Cárdenas, Gernot Strohmeier, Alessandra Luchini

Cholesterol is an essential component of mammalian membranes and is known to induce a series of physicochemical changes in the lipid bilayer. Such changes include the formation of liquid-ordered phases with an increased thickness and a configurationa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dd3d440e21b6596238885d204514df
https://hdl.handle.net/11391/1545249