Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gernot Langer"'
Autor:
Anders Friberg, Hartmut Rehwinkel, Duy Nguyen, Vera Pütter, Maria Quanz, Jörg Weiske, Uwe Eberspächer, Iring Heisler, Gernot Langer
Publikováno v:
ACS Omega, Vol 5, Iss 22, Pp 13034-13041 (2020)
Externí odkaz:
https://doaj.org/article/b464774c28454d519fbffbf316422343
Autor:
Reinhard Nubbemeyer, Judith Günther, Federica Morandi, Gernot Langer, Dieter Moosmayer, Peter Muhn, Bernhard Lindenthal, Ulrich Lücking, Marcus Koppitz, Hilmar Weinmann, Martina Schäfer, Ronald Kühne, Dieter Heldmann, Anna K. Schrey, Alexander Walter, Ulrike Röhn, Lothar Sobek, Katrin Nowak-Reppel, Kuhnke Joachim, Lars Wortmann
Publikováno v:
Journal of medicinal chemistry. 62(22)
The human luteinizing hormone receptor (hLH-R) is a member of the glycoprotein hormone family of G-protein-coupled receptors (GPCRs), activated by luteinizing hormone (hLH) and essentially involved in the regulation of sex hormone production. Thus, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c682e5fe6dba70d06105a046a496c9
https://pubmed.ncbi.nlm.nih.gov/31670515
https://pubmed.ncbi.nlm.nih.gov/31670515
Autor:
Stefan Bäurle, Olaf Peters, Gernot Langer, Ludwig Zorn, Antonius Ter Laak, Nico Bräuer, Ulrich Bothe, Daryl S. Walter, Jens Nagel, Thomas M. Zollner, Thorsten Blume, Cornelia Preusse, Antje Rottmann, Andreas Steinmeyer, Dieter Heldmann
Publikováno v:
Journal of medicinal chemistry. 62(5)
The presence and growth of endometrial tissue outside the uterine cavity in endometriosis patients are primarily driven by hormone-dependent and inflammatory processes-the latter being frequently associated with severe, acute, and chronic pelvic pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e5e05b956c3b01375f513a8d2d40bc
https://pubmed.ncbi.nlm.nih.gov/30707023
https://pubmed.ncbi.nlm.nih.gov/30707023
Autor:
Gernot, Langer
Publikováno v:
Handbook of experimental pharmacology. 232
The impressive advances in the generation and interpretation of functional omics data have greatly contributed to a better understanding of the (patho-)physiology of many biological systems and led to a massive increase in the number of specific targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e479e6ed2a952175ce0bc9af39db9bf
https://pubmed.ncbi.nlm.nih.gov/26424721
https://pubmed.ncbi.nlm.nih.gov/26424721
Autor:
Gernot Langer
Publikováno v:
New Approaches to Drug Discovery ISBN: 9783319289120
The impressive advances in the generation and interpretation of functional omics data have greatly contributed to a better understanding of the (patho-)physiology of many biological systems and led to a massive increase in the number of specific targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f5b55ec36a2d0691625ab45a614777
https://doi.org/10.1007/164_2015_18
https://doi.org/10.1007/164_2015_18
Autor:
Helmut Klocker, Andrea Nestl, Andrew C.B. Cato, Gernot Langer, Sigrun Mink, Hermann Rogatsch, L. Shatkina
Publikováno v:
Molecular and Cellular Biology. 23:7189-7197
Molecular chaperones and cochaperones belong to a group of unrelated proteins that mediate the correct assembly of other proteins but are not themselves components of the final structure (2). In steroid receptor action, they are thought to interact w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef545ca7a30b1eaf7834289ba4f9564
https://doi.org/10.1128/mcb.23.20.7189-7197.2003
https://doi.org/10.1128/mcb.23.20.7189-7197.2003
Autor:
Andrew C.B. Cato, Gernot Langer, Thomas Petri, Marja Jäättelä, Jean Schneikert, Susanne Hübner, Jennifer Reed
Publikováno v:
The EMBO Journal. 19:6508-6516
Receptor-associating protein 46 (RAP46) is a cochaperone that regulates the transactivation function of several steroid receptors. It is transported into the nucleus by a liganded glucocorticoid receptor where it downregulates DNA binding and transac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4197a04a6131e1517ff1a4ee037ddd1
https://doi.org/10.1093/emboj/19.23.6508
https://doi.org/10.1093/emboj/19.23.6508
Publikováno v:
Journal of Cellular Biochemistry. 66:184-196
The transcription factors of the nuclear hormone receptor family regulate gene expression via a complex network of macromolecular interactions. The ligand dependent activity of the vitamin D receptor is of particular interest because it modulates gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27863aa4e9037ce43086a0e6ed19aeb1
https://doi.org/10.1002/(sici)1097-4644(19970801)66:2<184::aid-jcb6>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19970801)66:2<184::aid-jcb6>3.0.co
Publikováno v:
Gene. 161:287-292
A reporter plasmid coding for the low-molecular-weight (low-M(r)) form of single-chain urokinase-type plasminogen activator (low-M(r) u-PA; Leu144-Leu411) has been constructed and used to analyze promoter activity. Vectors containing the low-M(r) u-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7e9ec33882dd87a673eddcd12c993e
https://doi.org/10.1016/0378-1119(95)00220-z
https://doi.org/10.1016/0378-1119(95)00220-z
Autor:
Christiane Otto, Iris Fuchs, Karl-Heinrich Fritzemeier, Beate Rohde-Schulz, Reinhard Nubbemeyer, Katja Prelle, Mario Klewer, Gilda Schwarz, Dominic E.A. Brittain, Gernot Langer, Benjamin Bader
Publikováno v:
Endocrinology. 149(10)
The classical estrogen receptor (ER) mediates genomic as well as rapid nongenomic estradiol responses. In case of genomic responses, the ER acts as a ligand-dependent transcription factor that regulates gene expression in estrogen target tissues. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5500b067f30dfa60271e021e9e7d9181
https://pubmed.ncbi.nlm.nih.gov/18566127
https://pubmed.ncbi.nlm.nih.gov/18566127