Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gernot Gradehandt"'
Publikováno v:
European Journal of Immunology. 26:1050-1057
Mycoplasma cause several diseases in man and animals. Some strains can chronically infect humans, leading to fever or inflammatory syndromes such as arthritis, particularly in immunosuppressed patients. A set of pathogenicity factors shared by many m
Autor:
Gernot Gradehandt, Erwin Rüde, Anastassia Pavlidou, Mansour Mohamadzadeh, Jürgen Knop, Alexander Enk
Publikováno v:
European journal of immunology. 24(12)
The antibody 4F7 was reported to recognize an epitope expressed on dendritic cells (DC) from various tissues. To study the ability of splenic 4F7+ dendritic cells to process antigen for presentation to CD4+ T cells, DC were enriched using a separatio
Autor:
Silke Milbradt, Johannes Hampl, Erwin Rüde, Nadja Kleber, Christina Lobron, Gernot Gradehandt, Burkhard Schmidt
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461362722
The antigen-specific activation of CD4-positive T helper cells depends on the recognition of a complex of MHC class II molecules and an antigen-derived peptide on the surface of antigen-presenting cells (APC). For most antigens generation of this MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::189e3848fffaa42013bdfd62de83618d
https://doi.org/10.1007/978-1-4615-2930-9_4
https://doi.org/10.1007/978-1-4615-2930-9_4
Autor:
Margot Meyer-Delius, Dimitrij Plachov, Gernot Gradehandt, Hans-Gregor Gattner, Johannes Hampl, Hubert Kalbacher, Wolfgang Voelter, Erwin Rüde
Publikováno v:
Molecular immunology. 28(4-5)
The requirements for insulin presentation and recognition by A alpha b A beta b- and A alpha b A beta k-restricted mouse T cells were studied using a variety of derivatives of the insulin A chain. It was found that A chain peptides with irreversibly
Publikováno v:
European journal of immunology. 20(12)
Beef insulin as well as a chymotryptic A-chain fragment [BI-A1-14(SSO3-)3] need uptake by antigen-presenting cells (APC) for efficient presentation in combination with major histocompatibility complex class II molecules to insulin-specific T cells. T
Autor:
Stefan Prechtl, Peter Rohwer, Susan P.C. Cole, Michael Lohoff, Gernot Gradehandt, Frank Sommer, Martin Roellinghoff, Brenda D. Stride, Roger G. Deeley, Edgar Schmitt
Publikováno v:
Immunology Letters. 56:353
Publikováno v:
Immunological reviews. 106
In this study we investigated aspects of antigen processing using insulin and insulin A chain-derived fragments as model antigens in Ab alpha Ak beta-restricted T-cell stimulation. Similarly to other proteins, the immunodominant region of insulin rec