Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Gernot, Beutel"'
Autor:
Evren Bayraktar, Theresa Graf, Francis A. Ayuk, Gernot Beutel, Olaf Penack, Thomas Luft, Nicole Brueder, Gastone Castellani, H. Christian Reinhardt, Nicolaus Kröger, Dietrich W. Beelen, Amin T. Turki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Despite advances in allogeneic hematopoietic cell transplantation, acute graft-versus-host disease (aGVHD) remains its leading complication, yet with heterogeneous outcomes. Here, we analyzed aGVHD phenotypes and clinical classifications in
Externí odkaz:
https://doaj.org/article/bb726bc78632416a8d9d063e67a7b93f
Autor:
Halvard Bonig, Mareike Verbeek, Peter Herhaus, Krischan Braitsch, Gernot Beutel, Christoph Schmid, Nadine Müller, Gesine Bug, Michaela Döring, Arend von Stackelberg, Johanna Tischer, Francis Ayuk, Gerald Wulf, Udo Holtick, Lisa-Marie Pfeffermann, Bernd Jahrsdörfer, Hubert Schrezenmeier, Selim Kuci, Zyrafete Kuci, Anke Zens, Michael Tribanek, Robert Zeiser, Sabine Huenecke, Peter Bader
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Patients with steroid-refractory acute graft-versus-host disease (aGvHD) not tolerating/responding to ruxolitinib (RR-aGvHD) have a dismal prognosis. Methods We retrospectively assessed real-world outcomes of RR-aGvHD treated with
Externí odkaz:
https://doaj.org/article/1942e01c115d422bbf46c4611ede54dd
Autor:
Halvard Bonig, Mareike Verbeek, Peter Herhaus, Krischan Braitsch, Gernot Beutel, Christoph Schmid, Nadine Müller, Gesine Bug, Michaela Döring, Arend von Stackelberg, Johanna Tischer, Francis Ayuk, Gerald Wulf, Udo Holtick, Lisa‑Marie Pfeffermann, Bernd Jahrsdörfer, Hubert Schrezenmeier, Selim Kuci, Zyrafete Kuci, Anke Zens, Michael Tribanek, Robert Zeiser, Sabine Huenecke, Peter Bader
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/b531e2a3fa18414fbe6b2e7f1a58550c
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 13, Iss 1, Pp 70-74 (2023)
The largest study on cyclophosphamide pharmacokinetics in dialysis patients comprises of 6 subjects. In the 2 decades since these data were obtained, dialyser membranes, treatment intensities, and treatment duration have changed considerably making n
Externí odkaz:
https://doaj.org/article/c51a4801992e4faa989747f51a4ed989
Autor:
Ivan Odak, Lâle M. Bayir, Lennart Riemann, Ruth Sikora, Jessica Schneider, Yankai Xiao, Nora Möhn, Thomas Skripuletz, Gernot Beutel, Matthias Eder, Arnold Ganser, Reinhold Förster, Christian R. Schultze-Florey, Christian Koenecke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Variability or stability might have an impact on treatment success and toxicity of CD19 CAR T-cells. We conducted a prospective observational study of 12 patients treated with Tisagenlecleucel for CD19+ B-cell malignancies. Using a 31-color spectral
Externí odkaz:
https://doaj.org/article/5786ca34b273415fb85d64d76fb3aa83
Autor:
Nora Möhn, Susann Mahjoub, Laura Duzzi, Emily Narten, Lea Grote‐Levi, Gudrun Körner, Tabea Seeliger, Gernot Beutel, Benjamin‐Alexander Bollmann, Thomas Wirth, André Huss, Hayrettin Tumani, Imke Grimmelmann, Ralf Gutzmer, Philipp Ivanyi, Thomas Skripuletz, ICOG‐CCCH (Immune Cooperative Oncology Group; Comprehensive Cancer Center Hannover)
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9373-9383 (2023)
Abstract Background Oncological patients can benefit substantially from treatment with immune checkpoint inhibitors (ICI). However, there is a growing awareness of immune‐related adverse events (irAE). Especially ICI‐mediated neurological adverse
Externí odkaz:
https://doaj.org/article/fc59d8e698d2445d874c2607cff2f8e4
Autor:
Victoria Panagiota, Johanna Franziska Kerschbaum, Olaf Penack, Catarina M. Stein, Christopher M. Arends, Christian Koenecke, Paulina M. Strzelecka, Arnold Kloos, Laura Wiegand, Alina Lasch, Robert Altwasser, Adriane Halik, Razif Gabdoulline, Julia Thomson, Konstantin Weibl, Georg-Nikolaus Franke, Carolina Berger, Justin Hasenkamp, Francis Ayuk, Il-Kang Na, Gernot Beutel, Ulrich Keller, Lars Bullinger, Gerald Georg Wulf, Nicolaus Kröger, Vladan Vucinic, Michael Heuser, Frederik Damm
Publikováno v:
HemaSphere, Vol 7, Iss 10, p e957 (2023)
Recent evidence revealed important interactions between clonal hematopoiesis (CH) and cellular therapies established for the treatment of hematologic malignancies. The impact of CH on safety, efficacy, and outcome of chimeric antigen receptor (CAR) T
Externí odkaz:
https://doaj.org/article/3ee53a5fe55248a48a4f66fd724ad837
Autor:
Anna Christina Dragon, Luca Marie Beermann, Melina Umland, Agnes Bonifacius, Chiara Malinconico, Louisa Ruhl, Patrik Kehler, Johanna Gellert, Lisa Weiß, Sarah Mayer-Hain, Katharina Zimmermann, Sebastian Riese, Felicitas Thol, Gernot Beutel, Britta Maecker-Kolhoff, Fumiichiro Yamamoto, Rainer Blasczyk, Axel Schambach, Michael Hust, Michael Hudecek, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChimeric antigen receptor-engineered T cells (CAR-Ts) are investigated in various clinical trials for the treatment of cancer entities beyond hematologic malignancies. A major hurdle is the identification of a target antigen with high exp
Externí odkaz:
https://doaj.org/article/46ba9e9337d34affb73dc677378f3afa
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/64ba7bee04ce4a5dacb3e0c5a5d0b82f
Autor:
Katja Krüger, Martin Wichmann, Razif Gabdoulline, Katharina Götze, Krischan Braitsch, Franziska Modemann, Walter Fiedler, Arne Trummer, Jürgen Krauter, Stephan Kaun, Susanne Rotermund, Andreas Voß, Gudrun Goehring, Yvonne Behrens, Felicitas Thol, Matthias Eder, Gernot Beutel, Michael Stadler, Michael Heuser, Rabia Shahswar
Publikováno v:
HemaSphere, Vol 7, p e19815ef (2023)
Externí odkaz:
https://doaj.org/article/f4ec097299c942ab8ecfc9000edf757a