Tumor necrosis factor α promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis.

Autor: Greiner G; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.; Ihr Labor, Medical Diagnostic Laboratories, Vienna, Austria.; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Witzeneder N; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Klein K; Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria., Tangermann S; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria., Kodajova P; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria., Jaeger E; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Ratzinger F; Ihr Labor, Medical Diagnostic Laboratories, Vienna, Austria., Gerner MC; Division of Biomedical Science, University of Applied Sciences FH Campus Wien, Vienna, Austria., Jawhar M; Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany.; Department of Hematology and Oncology, Helios Pforzheim, Pforzheim, Germany., Baumgartner S; Department of Pediatrics and Adolescent Medicine, Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Medical University of Vienna, Vienna, Austria., Fruehwirth K; Medical Central Laboratory, State Hospital Feldkirch, Feldkirch, Austria., Schmetterer KG; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Zuber J; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Gleixner KV; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria., Mayerhofer M; Ihr Labor, Medical Diagnostic Laboratories, Vienna, Austria., Schwarzinger I; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Simonitsch-Klupp I; Department of Pathology, Medical University of Vienna, Vienna, Austria., Esterbauer H; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Baer C; Munich Leukemia Laboratory, Munich, Germany., Walter W; Munich Leukemia Laboratory, Munich, Germany., Meggendorfer M; Munich Leukemia Laboratory, Munich, Germany., Strassl R; Division of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Haferlach T; Munich Leukemia Laboratory, Munich, Germany., Hartmann K; Division of Allergy, Department of Dermatology, University Hospital Basel and University of Basel, Basel, Switzerland.; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland., Kenner L; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.; Department of Pathology, Medical University of Vienna, Vienna, Austria.; Christian Doppler Laboratory for Applied Metabolomics, Vienna, Austria.; Center for Biomarker Research in Medicine, Graz, Austria., Sperr WR; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria., Reiter A; Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany., Sexl V; University of Innsbruck, Innsbruck, Austria., Arock M; Department of Hematological Biology and French National Reference Center for Mastocytosis (CEREMAST), Pitié-Salpêtrière Hospital, Paris Sorbonne University, Paris, France., Valent P; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria., Hoermann G; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.; Munich Leukemia Laboratory, Munich, Germany.

Publikováno v: Blood [Blood] 2024 Mar 14; Vol. 143 (11), pp. 1006-1017.

A multi-omics based anti-inflammatory immune signature characterizes long COVID-19 syndrome.

Autor: Kovarik JJ; Department of Internal Medicine III, Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna 1090, Austria., Bileck A; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Hagn G; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Meier-Menches SM; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Frey T; Department of Laboratory Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Kaempf A; Department of Laboratory Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Hollenstein M; Department of Laboratory Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Shoumariyeh T; Department of Internal Medicine III, Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna 1090, Austria., Skos L; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Reiter B; Department of Laboratory Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Gerner MC; Division of Biomedical Science, University of Applied Sciences FH Campus Wien, Vienna, Austria., Spannbauer A; Department of Medicine II, Division of Cardiology, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Hasimbegovic E; Department of Medicine II, Division of Cardiology, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Schmidl D; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Garhöfer G; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Gyöngyösi M; Department of Medicine II, Division of Cardiology, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Schmetterer KG; Department of Laboratory Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, Vienna, Austria., Gerner C; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.

Publikováno v: IScience [iScience] 2023 Jan 20; Vol. 26 (1), pp. 105717. Date of Electronic Publication: 2022 Dec 05.

Epithelial Cell Line Derived from Endometriotic Lesion Mimics Macrophage Nervous Mechanism of Pain Generation on Proteome and Metabolome Levels.

Autor: Neuditschko B; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090 Vienna, Austria., Leibetseder M; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Brunmair J; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Hagn G; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Skos L; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Gerner MC; Division of Biomedical Science, University of Applied Sciences, FH Campus Wien, Favoritenstraße 226, 1100 Vienna, Austria., Meier-Menches SM; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090 Vienna, Austria.; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria., Yotova I; Department of Obstetrics and Gynaecology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria., Gerner C; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria.

Publikováno v: Biomolecules [Biomolecules] 2021 Aug 17; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 17.

Packed red blood cells inhibit T-cell activation via ROS-dependent signaling pathways.

Autor: Gerner MC; Division of Biomedical Science, University of Applied Sciences FH Campus Wien, Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Bileck A; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Vienna, Austria., Janker L; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Vienna, Austria., Ziegler LS; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Öhlinger T; Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria., Raeven P; Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria., Müllner EW; Center of Medical Biochemistry, Max Perutz Labs (MPL), Medical University of Vienna, Vienna, Austria., Salzer U; Center of Medical Biochemistry, Max Perutz Labs (MPL), Medical University of Vienna, Vienna, Austria., Gerner C; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Vienna, Austria., Schmetterer KG; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Baron DM; Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria. Electronic address: david.baron@meduniwien.ac.at.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100487. Date of Electronic Publication: 2021 Mar 04.

The TGF-b/SOX4 axis and ROS-driven autophagy co-mediate CD39 expression in regulatory T-cells.

Autor: Gerner MC; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Ziegler LS; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Schmidt RLJ; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Krenn M; Department of Neurology, Medical University of Vienna, Vienna, Austria., Zimprich F; Department of Neurology, Medical University of Vienna, Vienna, Austria., Uyanik-Ünal K; Department of Surgery, Medical University of Vienna, Vienna, Austria., Konstantopoulou V; Department of Pediatrics, Medical University of Vienna, Vienna, Austria., Derdak S; Core Facility Genomics, Medical University of Vienna, Vienna, Austria., Del Favero G; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Vienna, Austria., Schwarzinger I; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria., Boztug K; Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Schmetterer KG; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Jun; Vol. 34 (6), pp. 8367-8384. Date of Electronic Publication: 2020 Apr 22.