Zobrazeno 1 - 10
of 23
pro vyhledávání: '"German Lizarralde"'
Publikováno v:
Neurobiology of Aging. 15:509-517
We have employed deconvolution analysis of 24-h serum GH, LH, and FSH concentration profiles to evaluate the nature of age-associated changes in GH, LH, and FSH secretion and disappearance in healthy older individuals. Our findings indicate that heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b640b300fe434b76b426ca794f83bf
https://doi.org/10.1016/0197-4580(94)90089-2
https://doi.org/10.1016/0197-4580(94)90089-2
Publikováno v:
Acta Endocrinologica. 128:521-528
In the present study, we investigated the coordinate kinetic response of the corticotropic axis to the acute metabolic stress of hypoglycemia by applying deconvolution analysis to adrenocorticotropin (ACTH), β-endorphin and cortisol concentration-ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2519644bdf9d52aed2e14f755db34555
https://doi.org/10.1530/acta.0.1280521
https://doi.org/10.1530/acta.0.1280521
Autor:
Ali Iranmanesh, Michael O. Thorner, Johannes D. Veldhuis, William S. Evans, Mary Lee Vance, German Lizarralde
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 76:587-593
In the male rodent and primate, fasting or severe caloric restriction significantly decreases serum testosterone concentrations, putatively via inducing secondary hypogonadotrophism. To clarify this presumptive pathophysiology, we have used: 1) a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbe5adad9ea203f8c2ce9e1914c50ce
https://doi.org/10.1210/jcem.76.3.8445014
https://doi.org/10.1210/jcem.76.3.8445014
Autor:
German Lizarralde, Alexander D. Zwart, Michael J. Wilkowski, Johannes D. Veldhuis, Warren K. Bolton, Randall J. Urban, Ali Iranmanesh
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 76:648-654
To investigate the nature of putative disturbances in pulsatile gonadotropin (LH) secretion in men with chronic renal failure, we undertook blood sampling at 10-min intervals for 24 h in 9 hemodialysis-dependent uremic men and 16 community- and age-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912be157251d09575443e124b7370c3d
https://doi.org/10.1210/jcem.76.3.8445020
https://doi.org/10.1210/jcem.76.3.8445020
Autor:
German Lizarralde, Johannes D. Veldhuis, Michael L. Johnson, Ali Iranmanesh, Randall J. Urban
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 75:707-713
To evaluate the impact of healthy aging on specific features of endogeneous LH secretion and clearance, we applied deconvolution analysis to 24-h serum immunoradiometric LH concentration series obtained in normal men whose ages ranged from 21-73 yr.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c8d9bd58ca4bcfe0b7d3f5e4269f8e
https://doi.org/10.1210/jcem.75.3.1517359
https://doi.org/10.1210/jcem.75.3.1517359
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 74:559-564
Primary hypothyroidism is a presumptive proximate basis for increased serum PRL concentrations. However, most studies to date have been performed in females and do not address the possible effect of sex differences. In the present study we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05e80b52aeded90fb0aa331580ba1cf
https://doi.org/10.1210/jcem.74.3.1740490
https://doi.org/10.1210/jcem.74.3.1740490
Publikováno v:
Chronobiology International. 9:371-379
Because of confounding effects of subject-specific and hormone-specific metabolic clearance, the nature of anterior pituitary secretory events in vivo is difficult to ascertain. We review an approach to this problem, in which deconvolu-tion analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb041b650e70077f61d5bdb673f90b4
https://doi.org/10.3109/07420529209064549
https://doi.org/10.3109/07420529209064549
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 71:1276-1283
Recent studies in the rat and rhesus monkey have disclosed apparently high frequency in vivo ACTH release episodes. While the circadian pattern of plasma ACTH concentrations has been known for many years, the exact frequency of ultradian pulsatile AC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0d48a0f96f2daae245c8753bbd7c42
https://doi.org/10.1210/jcem-71-5-1276
https://doi.org/10.1210/jcem-71-5-1276
Publikováno v:
Journal of Biological Rhythms. 5:247-255
Circadian and ultradian rhythms of plasma cortisol concentrations have been documented under physiological conditions in diverse animal species. Using a novel, biophysical convolution model to remove subject-specific metabolic clearance rates, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6c52010db408e19fb0e3a8e309f0eb
https://doi.org/10.1177/074873049000500306
https://doi.org/10.1177/074873049000500306
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 71:452-463
The ACTH-adrenal axis is a critical stress-responsive system with prominent circadian rhythmicity. To test the basis for the circadian ACTH physiology, we have used 1) a sensitive and specific two-site immunoradiometric assay to estimate plasma ACTH-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fafae2eaa7c8868452e32ec52e4ecc7d
https://doi.org/10.1210/jcem-71-2-452
https://doi.org/10.1210/jcem-71-2-452