Anti-Melanoma immunity and local regression of cutaneous metastases in melanoma patients treated with monobenzone and imiquimod; a phase 2 a trial

Autor: Hansje-Eva Teulings, Esther P. M. Tjin, Karina J. Willemsen, Stephanie van der Kleij, Sylvia ter Meulen, E. Helen Kemp, Gabrielle Krebbers, Carel J. M. van Noesel, Cornelis L. M. C. Franken, Jan W. Drijfhout, Cornelis J. M. Melief, Ludmila Nieuweboer-Krobotova, Omgo E. Nieweg, Jos A. van der Hage, J. P. Wietze van der Veen, Germaine N. Relyveld, Rosalie M. Luiten

Publikováno v: OncoImmunology, Vol 7, Iss 4 (2018)

Vitiligo development in melanoma patients during immunotherapy is a favorable prognostic sign and indicates breakage of tolerance against melanocytic/melanoma antigens. We investigated a novel immunotherapeutic approach of the skin-depigmenting compo

Externí odkaz: https://doaj.org/article/af615089565341d99d31eb4cf36a8748

Merkel cell carcinoma of the head and neck: emphasizing the risk of undertreatment

Autor: Peter J. F. M. Lohuis, Marianne B. Crijns, W. M. C. Klop, Ferdinand C. A. Timmer, Alfons J. M. Balm, Germaine N. Relyveld, Michiel W. M. van den Brekel

Publikováno v: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS), 273(5), 1243-1251. Springer Verlag
European Archives of Oto-Rhino-Laryngology, 273(5), 1243-1251. Springer Verlag
Timmer, F C A, Klop, W M C, Relyveld, G N, Crijns, M B, Balm, A J M, van den Brekel, M W M & Lohuis, P J F M 2016, ' Merkel cell carcinoma of the head and neck: emphasizing the risk of undertreatment ', European Archives of Oto-Rhino-Laryngology, vol. 273, no. 5, pp. 1243-1251 . https://doi.org/10.1007/s00405-015-3558-0

Merkel cell carcinoma (MCC) is a rare primary cutaneous neuroendocrine carcinoma. It occurs predominantly in the head and neck area and often behaves aggressively. In this single-institution retrospective observational cohort study, we describe the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b2aa632ac7d0bd3f2e1786bbcfe5eb
https://doi.org/10.1007/s00405-015-3558-0

Progressive Macular Hypomelanosis

Autor: Germaine N. Relyveld

Publikováno v: Pigmentary Skin Disorders ISBN: 9783319704180

Progressive macular hypomelanosis (PMH) is a skin disorder characterized by hypopigmented macules mostly on the trunk and sometimes on the extremities, buttocks, or face of young adults. It can be seen in patients of all skin types. Even though it ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::246c365ae4f22cbfe44f47850261b809
https://doi.org/10.1007/978-3-319-70419-7_10

Benzoyl peroxide/clindamycin/UVA is more effective than fluticasone/UVA in progressive macular hypomelanosis: a randomized study

Autor: Wiete Westerhof, Melanie M. Kingswijk, Johannes B. Reitsma, Germaine N. Relyveld, Jan D. Bos, Henk E. Menke

Publikováno v: Journal of the American Academy of Dermatology, 55(5), 836-843. Mosby Inc.

BACKGROUND: There is no effective treatment for progressive macular hypomelanosis. Recent findings indicate that Propionibacterium acnes may play a role in the pathogenesis. OBJECTIVES: We sought to compare the effectiveness of antimicrobial therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d510f89f8faaf15b7867fcd3cb8032b
https://doi.org/10.1016/j.jaad.2006.03.020

Ultrastructural findings in progressive macular hypomelanosis indicate decreased melanin production

Autor: Wiete Westerhof, KP Dingemans, Henk E. Menke, Germaine N. Relyveld, Jan D. Bos

Publikováno v: Journal of the European Academy of Dermatology and Venereology, 22(5), 568-574. Wiley-Blackwell

Background The pathogenesis of progressive macular hypomelanosis (PMH) is unknown. Recently, Westerhof et al. (Arch Dermatol 2004; 140: 210–214) hypothesized that Propionibacterium acnes produces a depigmenting factor that interferes with melanogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90fa5909089a55a33d3fdd0108a6323
https://pure.amc.nl/en/publications/ultrastructural-findings-in-progressive-macular-hypomelanosis-indicate-decreased-melanin-production(2f4755e5-59c1-48b9-9881-303441833818).html