Výsledky vyhledávání - "Germain Margall-Ducos"

Abstract 1843: Dicovery and characterization of a novel anti-human CXCR5 antibody for the treatment of B cell lymphomas

Autor: Nicola Beltraminelli, Mingjie Chen, Francisco Adrian, Stephanie Beq, Hombline Poullain, Clarisse Monchecourt, Jean Wang, Sami Ellouze, Carine George, Juying Li, Germain Margall-Ducos, Qian Zhang, Ayrin Kok, Yun-Yueh Lu, Muriel D. David, Liang Schweizer

Publikováno v: Cancer Research. 81:1843-1843

CXCR5 is a seven transmembrane protein coupled to protein G(i) expressed mainly on mature, resting B cells, follicular helper T cells (TFH), tonsillar B cells, and B cell lymphoma cells. CXCR5 is activated by its ligand CXCL13 and involved in cell mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe2fca74efbd0ee62050aee879c75264
https://doi.org/10.1158/1538-7445.am2021-1843

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Identification of a Novel Function of PiT1 Critical for Cell Proliferation and Independent of Its Phosphate Transport Activity

Autor: Chantal Desdouets, Germain Margall-Ducos, Laurent Beck, Gérard Friedlander, Christine Salaün, Christine Leroy

Publikováno v: Journal of Biological Chemistry. 284:31363-31374

PiT1 is a Na(+)-phosphate (P(i)) cotransporter located at the plasma membrane that enables P(i) entry into the cell. Its broad tissue expression pattern has led to the idea that together with the closely related family member PiT2, PiT1 is the ubiqui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8458edf36c219c1f799757f43caaa93
https://doi.org/10.1074/jbc.m109.053132

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KIF20A mRNA and Its Product MKlp2 Are Increased During Hepatocyte Proliferation and Hepatocarcinogenesis

Autor: Florence Bourgain-Guglielmetti, Dominique Wendum, Mathieu Boissan, Jessica Zucman-Rossi, Gabrielle Couchy, Marie-Lise Lacombe, Joëlle Sobczak-Thépot, Chantal Desdouets, Germain Margall-Ducos, Isabelle Gasnereau

Publikováno v: American Journal of Pathology
American Journal of Pathology, 2012, 180 (1), pp.131-140. ⟨10.1016/j.ajpath.2011.09.040⟩
American Journal of Pathology, American Society for Investigative Pathology, 2012, 180 (1), pp.131-140. ⟨10.1016/j.ajpath.2011.09.040⟩

International audience; Mitotic kinesin-like protein 2 (MKlp2), a microtubule-associated motor, is required during mitosis exit for the final step of cytokine;is. It also contributes to retrograde vesicular trafficking from the Golgi apparatus to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd597d639f25f081cfc1c7e29c9baef
https://hal.science/hal-01536637

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The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents

Autor: Grégory Merlen, Dominique Couton, Germain Margall-Ducos, Séverine Celton-Morizur, Chantal Desdouets

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2009, 119 (7), pp.1880-1887
Scopus-Elsevier
Journal of Clinical Investigation, 2009, 119 (7), pp.1880-1887

International audience; The formation of polyploid cells is part of the developmental program of several tissues. During postnatal development, binucleated tetraploid cells arise in the liver, caused by failure in cytokinesis. In this report, we have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264c7570e689055d13867b9818a181ce
https://www.hal.inserm.fr/inserm-00404399

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Liver tetraploidization is controlled by a new process of incomplete cytokinesis

Autor: Olivier Brégerie, Germain Margall-Ducos, Séverine Celton-Morizur, Dominique Couton, Chantal Desdouets

Publikováno v: Journal of cell science. 120(Pt 20)

Cytokinesis is precisely controlled in both time and space to ensure equal distribution of the genetic material between daughter cells. Incomplete cytokinesis can be associated with developmental or pathological cell division programs leading to tetr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a20c378cad098637dc19e8a36136216
https://pubmed.ncbi.nlm.nih.gov/17895361

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The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells

Autor: Christian Bréchot, Olivier Brégerie, Aude Robert, Claude Celati, Jacques-Emmanuel Guidotti, Germain Margall-Ducos, Chantal Desdouets

Publikováno v: Journal of cell science. 120(Pt 4)

Loss of normal primary cilia function in mammals is linked to proliferative diseases, such as polycystic kidney disease, suggesting a regulatory relationship between cilia and cell cycle. The primary cilium expressed by most mammalian cells is nuclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365e50a921d20f36c8c39153493c86a9
https://pubmed.ncbi.nlm.nih.gov/17264151

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