Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression

Autor: Nobuaki Kudo, Jan-Michael Peters, Germain M. Ducos, Nicole Firnberg, Karin G. Wirth, Anders Zetterberg, Chantal Desdouets, Gordana Wutz, Romeo Ricci, Kim Nasmyth, Janina Seznec, Shahryar Taghybeeglu

Publikováno v: The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, 2006, 172 (6), pp.847-860. ⟨10.1083/jcb.200506119⟩

International audience; Separase is a protease whose liberation from its inhibitory chaperone Securin triggers sister chromatid disjunction at anaphase onset in yeast by cleaving cohesin's kleisin subunit. We have created conditional knockout alleles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e2d2d2fc39f6da078400ac167a4421
https://doi.org/10.1083/jcb.200506119