Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Germain J. P. Fernando"'
Autor:
Jacob W. Coffey, Nicole M. D. van der Burg, Thippayawan Rananakomol, Hwee-Ing Ng, Germain J. P. Fernando, Mark A. F. Kendall
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 8, Pp n/a-n/a (2022)
Many types of microneedle (MN) arrays have been tested for delivery of vaccines to the skin. However, the effect of MN geometry/array design on antibody production is still unclear. Reports suggest that systemic immune responses may be affected by ho
Externí odkaz:
https://doaj.org/article/c1b1cfcd169e43cba45a1a892c3690cb
Autor:
Jovin J. Y. Choo, Laura J. Vet, Christopher L. D. McMillan, Jessica J. Harrison, Connor A. P. Scott, Alexandra C. I. Depelsenaire, Germain J. P. Fernando, Daniel Watterson, Roy A. Hall, Paul R. Young, Jody Hobson-Peters, David A. Muller
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Dengue viruses (DENV) cause an estimated 390 million infections globally. With no dengue-specific therapeutic treatment currently available, vaccination is the most promising strategy for its control. A wide range of DENV vaccines are in dev
Externí odkaz:
https://doaj.org/article/3a288fab6e9c432db1197a1c7a39ffd8
Autor:
Christopher L. D. McMillan, Armira Azuar, Jovin J. Y. Choo, Naphak Modhiran, Alberto A. Amarilla, Ariel Isaacs, Kate E. Honeyman, Stacey T. M. Cheung, Benjamin Liang, Maria J. Wurm, Paco Pino, Joeri Kint, Germain J. P. Fernando, Michael J. Landsberg, Alexander A. Khromykh, Jody Hobson-Peters, Daniel Watterson, Paul R. Young, David A. Muller
Publikováno v:
Vaccines, Vol 10, Iss 4, p 578 (2022)
The ongoing coronavirus disease 2019 (COVID-19) pandemic continues to disrupt essential health services in 90 percent of countries today. The spike (S) protein found on the surface of the causative agent, the SARS-CoV-2 virus, has been the prime targ
Externí odkaz:
https://doaj.org/article/047b2bd3483b4cd9b6da0a66f2543ada
Autor:
Jovin J. Y. Choo, Christopher L. D. McMillan, Germain J. P. Fernando, Roy A. Hall, Paul R. Young, Jody Hobson-Peters, David A. Muller
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1301 (2021)
Alternative delivery systems such as the high-density microarray patch (HD-MAP) are being widely explored due to the variety of benefits they offer over traditional vaccine delivery methods. As vaccines are dry coated onto the HD-MAP, there is a need
Externí odkaz:
https://doaj.org/article/c3781db295914ec3b1fdb0bb6b7d13c9
Autor:
Alberto A. Amarilla, David A. Muller, Naphak Modhiran, Nigel A.J. McMillan, Aroon Supramaniam, Ariel Isaacs, Jovin J Y Choo, Helle Bielefeldt-Ohmann, Christopher L. D. McMillan, Adi Idris, Gabrielle E. Kelly, Michael J. Landsberg, Germain J. P. Fernando, Stacey T. M. Cheung, Daniel Watterson, Benjamin Liang, Armira Azuar, Paul R. Young, Alexander A. Khromykh, Dhruba Acharya
Publikováno v:
Science Advances
Description
Delivery of a SARS-CoV-2 vaccine to the skin of mice via microarray patches provides complete protection from challenge.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 160 million people and
Delivery of a SARS-CoV-2 vaccine to the skin of mice via microarray patches provides complete protection from challenge.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 160 million people and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2baf8da41a037cbeae0d9bacff413cb
https://doi.org/10.1126/sciadv.abj8065
https://doi.org/10.1126/sciadv.abj8065
Autor:
Germain J. P. Fernando, Hwee-Ing Ng, Mark A. F. Kendall, Zewen K. Tuong, Stefano C. Meliga, Ian H. Frazer, Alexandra C. I. Depelsenaire
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-12 (2019)
NPJ Vaccines
NPJ Vaccines
Chemical adjuvants are typically used to improve immune responses induced by immunisation with protein antigens. Here we demonstrate an approach to enhance immune responses that does not require chemical adjuvants. We applied microprojection arrays t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403b90b8945b67e07cd0d1dbfb3c32e1
http://link.springer.com/article/10.1038/s41541-019-0134-4
http://link.springer.com/article/10.1038/s41541-019-0134-4
Autor:
Christopher L. D. McMillan, Armira Azuar, Helle Bielefeldt-Ohmann, Gabrielle E. Kelly, Germain J. P. Fernando, David A. Muller, Ariel Isaacs, Daniel Watterson, Paul R. Young, Alberto A. Amarilla, Michael J. Landsberg, Nigel A.J. McMillan, Alexander A. Khromykh, Naphak Modhiran, Benjamin Liang, Stacey T. M. Cheung, Jovin J Y Choo, Dhruba Acharya, Adi Idris, Aroon Supramaniam
SARS-CoV-2 has infected over 160 million people and resulted in more than 3.3 million deaths, and we still face many challenges in the rollout of vaccines. Here, we use the high-density microarray patch to deliver a SARS-CoV-2 spike subunit vaccine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b1d6149fad1e334031f3cdabd3ac3c
https://doi.org/10.1101/2021.05.30.446357
https://doi.org/10.1101/2021.05.30.446357
Autor:
David A. Muller, Paul R. Young, Jessica J. Harrison, Connor A. P. Scott, Daniel Watterson, Jovin J Y Choo, Jody Hobson-Peters, Alexandra C. I. Depelsenaire, Laura J. Vet, Germain J. P. Fernando, Christopher L. D. McMillan, Roy A. Hall
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
NPJ Vaccines
NPJ Vaccines
Dengue viruses (DENV) cause an estimated 390 million infections globally. With no dengue-specific therapeutic treatment currently available, vaccination is the most promising strategy for its control. A wide range of DENV vaccines are in development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c712fe95c4721622fcb8b5ab7ef6a6
https://doi.org/10.1038/s41541-021-00328-1
https://doi.org/10.1038/s41541-021-00328-1
Autor:
Steve Rockman, Julian Hickling, Jason D. Lickliter, Christopher D. Anderson, Peter Treasure, Jesse Bodle, Angus Forster, Alexandra C. I. Depelsenaire, Germain J. P. Fernando, Margaret Veitch, Katey Witham, James W. Wells
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255282 (2021)
PLoS ONE
PLoS ONE
Microarray patches (MAPs) have the potential to be a safer, more acceptable, easier to use and more cost-effective method for administration of vaccines when compared to the needle and syringe. Since MAPs deliver vaccine to the dermis and epidermis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a5166256fb35f009048c86e0e6639a
https://doaj.org/article/61371d0df36f45c29c01e75d282c49e0
https://doaj.org/article/61371d0df36f45c29c01e75d282c49e0
Autor:
Nick S. Owens, Ashleigh E. Shannon, Stacey T. M. Cheung, Jin Zhang, Christiana Agyei-Yeboah, Germain J. P. Fernando, David A. Muller, Mark A. F. Kendall, Simon R. Corrie, Daniel Watterson, Paul R. Young, Alexandra C. I. Depelsenaire
Publikováno v:
Vaccines
Vaccines, Vol 7, Iss 4, p 189 (2019)
Volume 7
Issue 4
Vaccines, Vol 7, Iss 4, p 189 (2019)
Volume 7
Issue 4
Dengue virus is the most important arbovirus impacting global human health, with an estimated 390 million infections annually, and over half the world&rsquo
s population at risk of infection. While significant efforts have been made to develop e
s population at risk of infection. While significant efforts have been made to develop e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e11ab0281a9ef7fbf3f7eca864e8a0
https://pubmed.ncbi.nlm.nih.gov/31756967
https://pubmed.ncbi.nlm.nih.gov/31756967