Zobrazeno 1 - 10
of 1 140
pro vyhledávání: '"Germain J"'
Autor:
Jacob W. Coffey, Nicole M. D. van der Burg, Thippayawan Rananakomol, Hwee-Ing Ng, Germain J. P. Fernando, Mark A. F. Kendall
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 8, Pp n/a-n/a (2022)
Many types of microneedle (MN) arrays have been tested for delivery of vaccines to the skin. However, the effect of MN geometry/array design on antibody production is still unclear. Reports suggest that systemic immune responses may be affected by ho
Externí odkaz:
https://doaj.org/article/c1b1cfcd169e43cba45a1a892c3690cb
Autor:
Jovin J. Y. Choo, Laura J. Vet, Christopher L. D. McMillan, Jessica J. Harrison, Connor A. P. Scott, Alexandra C. I. Depelsenaire, Germain J. P. Fernando, Daniel Watterson, Roy A. Hall, Paul R. Young, Jody Hobson-Peters, David A. Muller
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Dengue viruses (DENV) cause an estimated 390 million infections globally. With no dengue-specific therapeutic treatment currently available, vaccination is the most promising strategy for its control. A wide range of DENV vaccines are in dev
Externí odkaz:
https://doaj.org/article/3a288fab6e9c432db1197a1c7a39ffd8
Autor:
Alexandra C I Depelsenaire, Katey Witham, Margaret Veitch, James W Wells, Christopher D Anderson, Jason D Lickliter, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, Germain J P Fernando, Angus H Forster
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255282 (2021)
Microarray patches (MAPs) have the potential to be a safer, more acceptable, easier to use and more cost-effective method for administration of vaccines when compared to the needle and syringe. Since MAPs deliver vaccine to the dermis and epidermis,
Externí odkaz:
https://doaj.org/article/61371d0df36f45c29c01e75d282c49e0
Autor:
Christopher L. D. McMillan, Armira Azuar, Jovin J. Y. Choo, Naphak Modhiran, Alberto A. Amarilla, Ariel Isaacs, Kate E. Honeyman, Stacey T. M. Cheung, Benjamin Liang, Maria J. Wurm, Paco Pino, Joeri Kint, Germain J. P. Fernando, Michael J. Landsberg, Alexander A. Khromykh, Jody Hobson-Peters, Daniel Watterson, Paul R. Young, David A. Muller
Publikováno v:
Vaccines, Vol 10, Iss 4, p 578 (2022)
The ongoing coronavirus disease 2019 (COVID-19) pandemic continues to disrupt essential health services in 90 percent of countries today. The spike (S) protein found on the surface of the causative agent, the SARS-CoV-2 virus, has been the prime targ
Externí odkaz:
https://doaj.org/article/047b2bd3483b4cd9b6da0a66f2543ada
Autor:
Angus H Forster, Katey Witham, Alexandra C I Depelsenaire, Margaret Veitch, James W Wells, Adam Wheatley, Melinda Pryor, Jason D Lickliter, Barbara Francis, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, Germain J P Fernando
Publikováno v:
PLoS Medicine, Vol 17, Iss 3, p e1003024 (2020)
BACKGROUND:The Vaxxas high-density microarray patch (HD-MAP) consists of a high density of microprojections coated with vaccine for delivery into the skin. Microarray patches (MAPs) offer the possibility of improved vaccine thermostability as well as
Externí odkaz:
https://doaj.org/article/ccf4986e714c4d7486a7312cd803f8b1
Autor:
Jovin J. Y. Choo, Christopher L. D. McMillan, Germain J. P. Fernando, Roy A. Hall, Paul R. Young, Jody Hobson-Peters, David A. Muller
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1301 (2021)
Alternative delivery systems such as the high-density microarray patch (HD-MAP) are being widely explored due to the variety of benefits they offer over traditional vaccine delivery methods. As vaccines are dry coated onto the HD-MAP, there is a need
Externí odkaz:
https://doaj.org/article/c3781db295914ec3b1fdb0bb6b7d13c9
Autor:
Frances E Pearson, Celia L McNeilly, Michael L Crichton, Clare A Primiero, Sally R Yukiko, Germain J P Fernando, Xianfeng Chen, Sarah C Gilbert, Adrian V S Hill, Mark A F Kendall
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67888 (2013)
The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical
Externí odkaz:
https://doaj.org/article/939bada31aad4beab2f46dab10020487
Autor:
Adama Sow, Issa Sidibé, Zakaria Bengaly, Augustin Z Bancé, Germain J Sawadogo, Philippe Solano, Marc J B Vreysen, Renaud Lancelot, Jeremy Bouyer
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37124 (2012)
BACKGROUND: Tsetse flies are the cyclical vectors of African trypanosomosis that constitute a major constraint to development in Africa. Their control is an important component of the integrated management of these diseases, and among the techniques
Externí odkaz:
https://doaj.org/article/2c5bb2d49990462faaa1abc38aaf95aa
Autor:
Germain J P Fernando, Xianfeng Chen, Tarl W Prow, Michael L Crichton, Emily J Fairmaid, Michael S Roberts, Ian H Frazer, Lorena E Brown, Mark A F Kendall
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10266 (2010)
BackgroundOver 14 million people die each year from infectious diseases despite extensive vaccine use [1]. The needle and syringe--first invented in 1853--is still the primary delivery device, injecting liquid vaccine into muscle. Vaccines could be f
Externí odkaz:
https://doaj.org/article/513f0894b14147b3946ebd930b55e4f0