Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Germ cell cancers"'
Publikováno v:
Medicina, Vol 59, Iss 5, p 916 (2023)
Standard care for stage I testicular germ cell cancers (seminomatous—STC or non-seminomatous—NSTC) is orchiectomy followed by active surveillance, 1 or 2 cycles of adjuvant chemotherapy, surgery or radiotherapy. The decision on the adjuvant thera
Externí odkaz:
https://doaj.org/article/e3049bb2b33d416b90e58cd65c418500
Autor:
Ben Tran, Ciara Conduit
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Owing to advances in treatment paradigms across the last five decades, testicular cancer is now eminently curable. However, current serum tumour and imaging biomarkers lack adequate sensitivity, specificity, and predictive value. Subsequently, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc25d0c753eee7611d66b0d38cd87cb
https://doaj.org/article/0daa894ba6574bd2abc3eab7689e2b47
https://doaj.org/article/0daa894ba6574bd2abc3eab7689e2b47
Autor:
Daniel eEdsgärd, Marlene eDalgaard, Nils eWeinhold, Agata eWesolowska, Ewa eRajpert-De Meyts, Anne Marie eOttesen, Anders eJuul, Niels E. eSkakkebæk, Thomas eSkøt Jensen, Ramneek eGupta, Henrik eLeffers, Søren eBrunak
Publikováno v:
Frontiers in Endocrinology, Vol 4 (2013)
Testicular germ cell cancer (TGCC) is one of the most heritable forms of cancer. Previous genome-wide association studies have focused on single nucleotide polymorphisms (SNPs), largely ignoring the influence of copy number variants (CNVs). Here we p
Externí odkaz:
https://doaj.org/article/7ff9f2f5e27e4d2da6bdd2a4788b8ffc
Autor:
Edward Kanfer, Deshveer S Babra, Marcia Hall, Anand Sharma, Amir Yazdan, Priya V Joshi, Magdalene Joseph, Nikhil Vasdev, Andrew Gogbashian
Publikováno v:
In Vivo
Background/Aim: High-dose chemotherapy (HDCT) and stem cell transplantation (SCT) have been established as the standard of care in patients with relapsed germ cell tumours (GCTs). We evaluated the safety, efficacy and tolerability of HDCT/ SCT in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0704b3cf7dbc58728b3f16675a3d84f9
https://pubmed.ncbi.nlm.nih.gov/33144484
https://pubmed.ncbi.nlm.nih.gov/33144484
Publikováno v:
International Brazilian Journal of Urology, Vol 29, Iss 5, Pp 431-433 (2003)
INTRODUCTION: We present the case of a patient with urethral metastasis of a lung carcinoma with germinative cell features. CASE REPORT: A White, 57-year old man underwent urologic assessment due to gross hematuria. Patient was being treated with che
Externí odkaz:
https://doaj.org/article/80fa715e57654e0abf7d3d958ad5089f
Autor:
Hubert Schorle, Isabell Arndt, Rakesh Sharma, Stefanie Riesenberg, Michael Hölzel, Glen Kristiansen, Simon Schneider, Sina Jostes, Daniel Nettersheim
Publikováno v:
British Journal of Cancer
Background: Cancer/testis-antigens (CTAs) are specifically expressed in human malignancies and testis tissue, but their molecular functions are poorly understood. CTAs serve as regulators of gene expression, cell cycle and spermatogenesis, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b158d508bc9656e01be287c572c01ff1
http://europepmc.org/articles/PMC4985348
http://europepmc.org/articles/PMC4985348
Autor:
Anja Lorch, Jörg Beyer
Publikováno v:
Cancer. 123:2190-2192
High cure rates and long-term survival for patients with germ cell cancer create an obligation to get it absolutely right. This can best be achieved by interdisciplinary teams at specialized units that see large numbers of germ cell cancer patients r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce31ac61debd5e1d574aa2f6a902510
https://doi.org/10.1002/cncr.30751
https://doi.org/10.1002/cncr.30751
Autor:
Alan Horwich
Publikováno v:
American Society of Clinical Oncology Educational Book. :e249-e252
Germ cell cancers of the testis arise in young adults, and, if identified in stage I, have an excellent prognosis. Thus, we should minimize management-related toxicities. Surveillance (observation) following orchiectomy can avoid further treatment; h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3b6640d78247ae6dcf09c34ea782f2
https://doi.org/10.14694/edbook_am.2015.35.e249
https://doi.org/10.14694/edbook_am.2015.35.e249
Akademický článek
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Autor:
Hajnalka Németh, Szabolcs Horváth, Krisztina Kormosói-Tóth, Zsófia Küronya, Krisztina Bíró, Lajos Géczi
Publikováno v:
Pathology & Oncology Research. 21:495-499
Testicular germ cell cancers are relatively rare with the incidence rate of 3.7 cases per 100,000 per year. Nevertheless they represent the most frequent malignant tumors in men aged 15–35 years. Pure choriocarcinoma comprises only 1 % of all testi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb489dd62d62dc964b6aa3c8304e946d
https://doi.org/10.1007/s12253-014-9842-2
https://doi.org/10.1007/s12253-014-9842-2