Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Germán, Iñiguez"'
Autor:
Diana Ponce, Fernando Rodríguez, José P. Miranda, Alexandra M. Binder, José L. Santos, Karin B. Michels, Gordon B. Cutler, Ana Pereira, Germán Iñiguez, Verónica Mericq
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Biochemical premature adrenarche is defined by elevated serum DHEAS [≥40 μg/dL] before age 8 y in girls. This condition is receiving more attention due to its association with obesity, hyperinsulinemia, dyslipidemia, and polycystic ovary syndrome.
Externí odkaz:
https://doaj.org/article/7428a6c1936f4beaa926de779c9b4405
Autor:
Germán Iñiguez, Pedro Gallardo, Juan Jose Castro, Rene Gonzalez, Mirna Garcia, Elena Kakarieka, Sebastian San Martin, Maria Cecilia Johnson, Verónica Mericq, Fernando Cassorla
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Introduction: Fetal growth restriction may be the consequence of maternal, fetal, or placental factors. The insulin-like growth factors (IGFs) are major determinants of fetal growth, and are expressed in the mother, fetus and placenta in most species
Externí odkaz:
https://doaj.org/article/98c55c2489534fbd80149c5ca925576c
Autor:
Erika Castaño, Lorena Caviedes, Sandra Hirsch, Miguel Llanos, Germán Iñiguez, Ana María Ronco
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170389 (2017)
Folate deficiency during pregnancy has been related to low birth weight, preterm (PT) birth and other health risks in the offspring; however, it is unknown whether prematurity is related to low folate transport through the placenta due to altered exp
Externí odkaz:
https://doaj.org/article/bfdb1aeb0b494d9b9f2cc8134bc47c93
Autor:
Oscar Castillo-Valenzuela, Lissette Duarte, Miguel Arredondo, Germán Iñiguez, Luis Villarroel, Francisco Pérez-Bravo
Publikováno v:
Nutrients; Volume 15; Issue 7; Pages: 1707
Objective: To analyze the nutritional status and plasma levels of vitamins and minerals in a cohort of Chilean children between 4 and 14 years old from three cities in Chile (Santiago, Antofagasta, and Concepcion). Design: This is a descriptive analy
Autor:
Lissette Duarte, Oscar Castillo-Valenzuela, Miguel Arredondo-Olguín, Germán Iñiguez, Francisco Pérez-Bravo
Publikováno v:
European Journal of Clinical Nutrition. 76:899-901
Background Vitamin D [25(OH)D] is essential for normal bone development and maintenance. Furthermore, its deficiency has been associated with obesity, cardiovascular diseases, insulin resistance, autoimmune diseases, and certain cancers. Objective To
Autor:
Kristian Almstrup, B. Julio Soto, G. Verónica Mericq, Anders Juul, Camila Corvalán, Alexander S Busch, Ana Pereira, Germán Iñiguez
Publikováno v:
Clinical Endocrinology. 93:296-304
Transient thelarche (TT), that is, the appearance, regression and subsequent reappearance of breast buds, is a frequent phenomenon, but little is known about pubertal transition in these girls.To describe pubertal progression, growth, genotypes, repr
Publikováno v:
Hormone Research in Paediatrics. 92:357-364
Objective: To assess whether the presence of high DHEAS (HD) at 7 years determines different timing, sequence, and rate of pubertal events, and whether it is associated with adrenal and/or ovarian hyperandrogenism and changes in ovarian morphology th
Autor:
Germán Iñiguez, Juan José Castro, Mirna Garcia, Elena Kakarieka, M Cecilia Johnson, Fernando Cassorla, Verónica Mericq
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102252 (2014)
The human placenta expresses the IGF-I and IGF-IR proteins and their intracellular signal components (IRS-1, AKT and mTOR). The aim of this study was to assess the IGF-IR content and activation of downstream signaling molecules in placentas from newb
Externí odkaz:
https://doaj.org/article/7a882b111e584270a3d413a69c2c5ac0
Autor:
Patricia López, Alejandra Avila, Ximena Gaete, Claudio Villarroel, Germán Iñiguez, Fernando Cassorla, Maria Isabel Hernandez, Gabriel Cavada
Publikováno v:
Journal of Pediatric Endocrinology and Metabolism. 30:561-568
Background: During puberty there is a physiologic increase in adrenal and ovarian androgens. It has been suggested that the somatotrophic axis may be related to the development of hyperandrogenism and anovulation in non-obese adult women with polycys
Autor:
Manouk van der Steen, Anita C. S. Hokken-Koelega, Ricardo Uauy, Alejandro Martinez-Aguayo, Verónica Mericq, Germán Iñiguez
Publikováno v:
Nature Reviews Endocrinology, 13(1), 50-62. Nature Publishing Group
Accumulating evidence suggests that both the intrauterine environment and growth during early life can influence the development of chronic noncommunicable diseases, such as type 2 diabetes mellitus and cardiovascular disease, in adulthood. Here, we