Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Germán, Ebensperger"'
Autor:
Felipe A. Beñaldo, Claudio Araya-Quijada, Germán Ebensperger, Emilio A. Herrera, Roberto V. Reyes, Fernando A. Moraga, Alexander Riquelme, Alejandro Gónzalez-Candia, Sebastián Castillo-Galán, Guillermo J. Valenzuela, María Serón-Ferré, Aníbal J. Llanos
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation and reduce vascular remo
Externí odkaz:
https://doaj.org/article/b228bfeb7ef44690add9f8bb2d5da097
Autor:
Sebastián Castillo-Galán, Daniela Parrau, Ismael Hernández, Sebastián Quezada, Marcela Díaz, Germán Ebensperger, Emilio A. Herrera, Fernando A. Moraga, Rodrigo Iturriaga, Aníbal J. Llanos, Roberto V. Reyes
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Calcium signaling is key for the contraction, differentiation, and proliferation of pulmonary arterial smooth muscle cells. Furthermore, calcium influx through store-operated channels (SOCs) is particularly important in the vasoconstrictor response t
Externí odkaz:
https://doaj.org/article/b24b10863fe842e38f05e3b9f4ae575e
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The authors previously demonstrated that newborn llama (NBLL) express high levels of α1 adrenergic receptors, which provide a potent vasoconstriction response when compared with newborn sheep (NBSH) gestated at sea level. However, data regarding the
Externí odkaz:
https://doaj.org/article/0e8e57fb5e1245ff911650a2e1439986
Autor:
Alejandro Gonzaléz-Candia, Pamela V. Arias, Simón A. Aguilar, Esteban G. Figueroa, Roberto V. Reyes, Germán Ebensperger, Aníbal J. Llanos, Emilio A. Herrera
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1658 (2021)
Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of this condition is perinatal hypoxia and oxidative stress. Thus, it is a pu
Externí odkaz:
https://doaj.org/article/505e4c815cb54758b1ed2fffa5ecb88a
Autor:
Felipe A. Beñaldo, Aníbal J. Llanos, Claudio Araya-Quijada, Auristela Rojas, Alejandro Gonzalez-Candia, Emilio A. Herrera, Germán Ebensperger, Gertrudis Cabello, Guillermo J. Valenzuela, María Serón-Ferré
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Neonatal lambs, as other neonates, have physiologically a very low plasma melatonin concentration throughout 24 h. Previously, we found that melatonin given to neonates daily for 5 days decreased heart weight and changed plasma cortisol and gene expr
Externí odkaz:
https://doaj.org/article/5881271bcd6e4a369d061f6d2ed95241
Autor:
Alejandro Gonzalez-Candia, Marcelino Veliz, Catalina Carrasco-Pozo, Rodrigo L. Castillo, J. Cesar Cárdenas, Germán Ebensperger, Roberto V. Reyes, Aníbal J. Llanos, Emilio A. Herrera
Publikováno v:
Redox Biology, Vol 22, Iss , Pp - (2019)
Chronic hypobaric hypoxia during fetal and neonatal life induces neonatal pulmonary hypertension. Hypoxia and oxidative stress are driving this condition, which implies an increase generation of reactive oxygen species (ROS) and/or decreased antioxid
Externí odkaz:
https://doaj.org/article/da4bcb30a36e4af6971119f72dbc1117
Autor:
Roberto V. Reyes, Sebastián Castillo-Galán, Ismael Hernandez, Emilio A. Herrera, Germán Ebensperger, Aníbal J. Llanos
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The pulmonary arteries are exquisitely responsive to oxygen changes. They rapidly and proportionally contract as arterial PO2 decrease, and they relax as arterial PO2 is re-established. The hypoxic pulmonary vasoconstriction (HPV) is intrinsic since
Externí odkaz:
https://doaj.org/article/5859e3a6953c47189e89a5a14a3b039a
Autor:
Cristian R. Astorga, Alejandro González-Candia, Alejandro A. Candia, Esteban G. Figueroa, Daniel Cañas, Germán Ebensperger, Roberto V. Reyes, Aníbal J. Llanos, Emilio A. Herrera
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Background: Chronic hypoxia and oxidative stress during gestation lead to pulmonary hypertension of the neonate (PHN), a condition characterized by abnormal pulmonary arterial reactivity and remodeling. Melatonin has strong antioxidant properties and
Externí odkaz:
https://doaj.org/article/060059dd8ed548d0b65d5779bd110caa
Autor:
Emilio A. Herrera, Aníbal J. Llanos, Emilia M. Sanhueza, Germán Ebensperger, Dino A. Giussani, Roberto V. Reyes
Publikováno v:
Journal of Applied Physiology. 129:152-161
Most mammals have a poor tolerance to hypoxia, and prolonged O2 restriction can lead to organ injury, particularly during fetal and early postnatal life. Nevertheless, the llama ( Lama Glama) has evolved efficient mechanisms to adapt to acute and chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8818313485da51b53d74196852517abe
https://doi.org/10.1152/japplphysiol.00800.2019
https://doi.org/10.1152/japplphysiol.00800.2019
Autor:
Simón A. Aguilar, Alejandro González-Candia, Emilio A. Herrera, Esteban G. Figueroa, Germán Ebensperger, Aníbal J. Llanos, Roberto V. Reyes, Pamela V. Arias
Publikováno v:
Antioxidants
Volume 10
Issue 11
Antioxidants, Vol 10, Iss 1658, p 1658 (2021)
Volume 10
Issue 11
Antioxidants, Vol 10, Iss 1658, p 1658 (2021)
Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of this condition is perinatal hypoxia and oxidative stress. Thus, it is a pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0107fa6f2027cdbc7f7db3e29ef30b